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The Veterinary clinics of North America. Equine practice2011; 27(3); 507-526; doi: 10.1016/j.cveq.2011.08.003

Toxins and adverse drug reactions affecting the equine nervous system.

Abstract: This article provides an overview of the more common toxins and adverse drug reactions, along with more rare toxins and reactions (Table 1), that result in neurologic dysfunction in horses. A wide variety of symptoms, treatments, and outcomes are seen with toxic neurologic disease in horses. An in-depth history and thorough physical examination are needed to determine if a toxin or adverse drug reaction is responsible for the clinical signs. Once a toxin or adverse drug reaction is identified, the specific antidote, if available, and supportive care should be administered promptly.
Publication Date: 2011-11-22 PubMed ID: 22100042DOI: 10.1016/j.cveq.2011.08.003Google Scholar: Lookup
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Summary

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The research article examines common and rare toxins as well as adverse drug reactions that can cause neurological dysfunction in horses. It provides an in-depth view on the symptoms, treatments and results associated with these toxic neurological diseases.

Understanding Toxins and Adverse Drug Reactions Affecting Equine Nervous System

  • The research describes an array of toxins and adverse drug reactions that horses often encounter and which can lead to neurologic dysfunction. These toxins can be common occurrences in the horses’ environment or more rare and less understood. These could be naturally occurring in the environment or induced by certain drugs.
  • In addition, the study elaborates how these components lead to a wide variety of symptoms that depict neurologic disease in horses. The severity and nature of these symptoms largely differ based on the type of toxin or drug reaction causing them.

Diagnosis and Treatment

  • The article highlights how comprehensive diagnosis is crucial in assessing the possibility of a toxin or adverse drug reaction as the culprit behind the observed clinical signs. This involves a detailed history taking and a thorough physical examination of the horse.
  • Once a toxin or adverse drug reaction has been identified, prompt treatment is crucial. Treatment involves administering the specific antidote, if available, alongside supportive care. Administering an antidote, designed to counteract the specific toxin or drug reaction, is the primary form of immediate treatment. Further, consistent supportive care aids the recovery process and sustains the overall health of the horse.

Cite This Article

APA
Dawson DR. (2011). Toxins and adverse drug reactions affecting the equine nervous system. Vet Clin North Am Equine Pract, 27(3), 507-526. https://doi.org/10.1016/j.cveq.2011.08.003

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 27
Issue: 3
Pages: 507-526

Researcher Affiliations

Dawson, Dominic R
  • William Pritchard Veterinary Medical Teaching Hospital, University of California, Davis, One Garrod Avenue, Davis, CA 95616, USA. drdawson@ucdavis.edu

MeSH Terms

  • Animals
  • Horse Diseases / chemically induced
  • Horses
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / veterinary
  • Toxins, Biological / poisoning
  • Veterinary Drugs / adverse effects

Citations

This article has been cited 1 times.
  1. Santifort KM, Mandigers PJJ. Dystonia in veterinary neurology. J Vet Intern Med 2022 Nov;36(6):1872-1881.
    doi: 10.1111/jvim.16532pubmed: 36086931google scholar: lookup