Treatment of equine cutaneous neoplasia by radiotherapy using iridium 192 linear sources.
Abstract: The treatment of equine cutaneous tumours by conventional or cryosurgical techniques can be limited where the position of the tumour makes radical excision or freezing impractical or dangerous. Radiotherapy provides an effective and practical alternative. The use of iridium pins with guide needles allows accurate positioning of sources and uniform radiation fields to be achieved. The subsequent removal of the pins reduces the period of incapacity and reduces the radiation risk when compared to permanently implanted sources. Twenty-seven tumours on 26 horses were treated by this method with a 100 per cent success rate after a single irradiation. The technique of implantation is described and the criteria used to select cases and to assess the efficacy of this treatment are discussed.
Publication Date: 1983-10-01 PubMed ID: 6641684DOI: 10.1111/j.2042-3306.1983.tb01824.xGoogle Scholar: Lookup
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- Journal Article
Summary
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The research corresponds to the successful treatment of skin tumors in horses through radiotherapy with iridium 192 linear sources. This method is deemed efficient especially when the tumor’s position restricts using other techniques like cryosurgery or radical excision.
About the Research
- The study involves the examination of equine cutaneous tumors, which are commonly observed skin tumors in horses. Conventional techniques like freezing or radical excision can sometimes be impractical or risky based on the tumor’s location.
- The research aims to improve upon these conventional treatments by employing a different method: radiotherapy. More specifically, the study uses iridium 192 linear sources in this radiotherapy.
- The researchers used a crucial tool in the form of iridium pins with guide needles. These tools allowed for accurate positioning of sources and achieving uniform radiation fields.
The Research Process
- The researchers used the method of implantation, the details of which are discussed in the research paper. This approach involves the placements of the iridium pins into the tumor to allow the iridium 192 to irradiate and treat the abnormal cells.
- Once the therapy was done, these pins were removed. The removal of pins not only reduces the duration for which the horse is incapacitated, but also lessens the radiation risk associated with permanently implanted sources.
Results and Findings
- The sample size for the research was 26 horses with 27 tumors. Impressively, the researchers observed a 100% success rate in treating these tumors with a single round of irradiation using the discussed method.
- The researchers also discussed the criteria used to select the cases for the study and to evaluate the effectiveness of this treatment.
Conclusion
- The study suggests that radiotherapy, specifically using iridium 192 linear sources, presents an effective and practical choice in treating equine cutaneous neoplasia, especially in instances where conventional or cryosurgical methods pose limitations.
- However, it’s crucial to consider that this method’s success involves careful case selection and accurately assessing the treatment’s effectiveness.
Cite This Article
APA
Wyn-Jones G.
(1983).
Treatment of equine cutaneous neoplasia by radiotherapy using iridium 192 linear sources.
Equine Vet J, 15(4), 361-365.
https://doi.org/10.1111/j.2042-3306.1983.tb01824.x Publication
Researcher Affiliations
MeSH Terms
- Animals
- Brachytherapy / methods
- Brachytherapy / veterinary
- Horse Diseases / radiotherapy
- Horses
- Iridium / therapeutic use
- Radioisotopes / therapeutic use
- Skin Neoplasms / radiotherapy
- Skin Neoplasms / veterinary
Citations
This article has been cited 4 times.- Poore LA, Duncan N, Williams J. Unilateral subcutaneous fibroma in the distal femoral region of a 5-year-old Nooitgedacht mare.. J S Afr Vet Assoc 2018 Dec 5;89(0):e1-e4.
- Nappert G, Lavoie JP, Sauvageau R, Scott DW. Le sarcoïde équin: présentation d'un cas clinique.. Can Vet J 1989 Nov;30(11):897-9.
- Carstanjen B, Jordan P, Lepage OM. Carbon dioxide laser as a surgical instrument for sarcoid therapy--a retrospective study on 60 cases.. Can Vet J 1997 Dec;38(12):773-6.
- Klein WR, Bras GE, Misdorp W, Steerenberg PA, de Jong WH, Tiesjema RH, Kersjes AW, Ruitenberg EJ. Equine sarcoid: BCG immunotherapy compared to cryosurgery in a prospective randomised clinical trial.. Cancer Immunol Immunother 1986;21(2):133-40.
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