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Tijdschrift voor diergeneeskunde2002; 127(11); 350-354;

[Treatment of equine sarcoids with cisplatin in arachid oil: a useful alternative?].

Abstract: At the Department of Equine Sciences at Utrecht University a study was performed on the treatment of sarcoids with the cytostatic drug cisplatin. Fourteen horses with 23 sarcoids were treated in the period 2000-2001. Complete regression was seen in 78% of the tumours. No systemic side-effects were encountered. Although treatment was easy to perform, the ALARA (As Low As Reasonably Achievable) principle should be followed when using cytostatics.
Publication Date: 2002-06-21 PubMed ID: 12073779
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Summary

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The research study was conducted at the Department of Equine Sciences, Utrecht University, to explore the possibility of treating equine sarcoids (type of skin tumor in horses) with the drug cisplatin. They found that 78% of the tumors regressed completely, with no systemic side effects reported.

Study Overview

  • The research was performed at the Department of Equine Sciences at Utrecht University, focusing on the use of the cytostatic drug, cisplatin, for treating equine sarcoids.
  • The study spanned from 2000 to 2001 and involved 14 horses with 23 tumors.

Results of the Study

  • The researchers found that 78% of the tumors treated showed complete regression, which indicates a strong positive response to the treatment.
  • Furthermore, it was observed during the study that no systemic (affecting the whole body) side effects were associated with the use of cisplatin in the treated horses.

Treatment Process and Safety Guidelines

  • The researchers have highlighted that the treatment process is easy to perform, implying that it could potentially be a practical solution in real-world settings.
  • However, they have also reiterated the importance of following the ALARA (As Low As Reasonably Achievable) principle when using cytostatic drugs like cisplatin. This principle emphasizes minimizing the exposure and hence potential harm caused by such drugs.

Cite This Article

APA
Spoormakers TJ, Klein WR, van Weeren PR. (2002). [Treatment of equine sarcoids with cisplatin in arachid oil: a useful alternative?]. Tijdschr Diergeneeskd, 127(11), 350-354.

Publication

ISSN: 0040-7453
NlmUniqueID: 0031550
Country: Netherlands
Language: dut
Volume: 127
Issue: 11
Pages: 350-354

Researcher Affiliations

Spoormakers, T J P
    Klein, W R
      van Weeren, P R

        MeSH Terms

        • Animals
        • Antineoplastic Agents / therapeutic use
        • Cisplatin / therapeutic use
        • Emulsions
        • Female
        • Horse Diseases / drug therapy
        • Horse Diseases / pathology
        • Horses
        • Male
        • Neoplasm Recurrence, Local / prevention & control
        • Neoplasm Recurrence, Local / veterinary
        • Prognosis
        • Skin Neoplasms / drug therapy
        • Skin Neoplasms / pathology
        • Skin Neoplasms / veterinary
        • Treatment Outcome

        Citations

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