Analyze Diet
The Veterinary record2006; 159(11); 337-341; doi: 10.1136/vr.159.11.337

Treatment of periocular and non-ocular sarcoids in 18 horses by interstitial brachytherapy with iridium-192.

Abstract: Treatment of the equine sarcoid has posed a significant challenge to clinicians for years and many different methods have been tried with varying success, including ionising radiation. The aim of this study was to review the efficacy of iridium-192 interstitial brachytherapy for the treatment of eight periocular sarcoids and 15 non-ocular sarcoids on 18 horses. All the periocular sarcoids and 13 of the 15 non-ocular sarcoids were treated successfully.
Publication Date: 2006-09-12 PubMed ID: 16963712DOI: 10.1136/vr.159.11.337Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article investigates the use of iridium-192 interstitial brachytherapy as a treatment for sarcoids in horses, and found it to be effective in treating both periocular and non-ocular sarcoids.

Objective of the Study

  • The primary goal of this research was to explore the effectiveness of iridium-192 interstitial brachytherapy in treating sarcoids in horses. Sarcoids, a common type of skin tumor in horses, have proven difficult to treat with traditional methods.

Methodology Used in the Study

  • The study focused on the treatment of eight periocular (around the eye) sarcoids and 15 non-ocular (not near the eye) sarcoids in 18 horses.
  • Iridium-192 interstitial brachytherapy, which is a type of targeted radiation therapy, was used as the treatment method.

Findings of the Study

  • All sarcoids around the eye were successfully treated with iridium-192 interstitial brachytherapy.
  • Out of the 15 non-ocular sarcoids, 13 were successfully treated with this method.
  • The results suggest that iridium-192 interstitial brachytherapy could be an effective treatment solution for equine sarcoids, regardless of their location on the horse’s body.

Significance of the Study

  • This research provides valuable insight into alternative treatment methods for equine sarcoids.
  • The findings could be particularly beneficial for veterinarians seeking more effective solutions to treat this common equine condition.
  • The study also contributes to the wider scientific understanding of how targeted radiation therapy can be used in veterinary medicine.

Cite This Article

APA
Byam-Cook KL, Henson FM, Slater JD. (2006). Treatment of periocular and non-ocular sarcoids in 18 horses by interstitial brachytherapy with iridium-192. Vet Rec, 159(11), 337-341. https://doi.org/10.1136/vr.159.11.337

Publication

ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 159
Issue: 11
Pages: 337-341

Researcher Affiliations

Byam-Cook, K L
  • Queen's Veterinary School Hospital, University of Cambridge, Madingley Road, Cambridge.
Henson, F M D
    Slater, J D

      MeSH Terms

      • Animals
      • Brachytherapy / methods
      • Brachytherapy / veterinary
      • Eye Diseases / radiotherapy
      • Eye Diseases / surgery
      • Eye Diseases / veterinary
      • Eye Neoplasms / radiotherapy
      • Eye Neoplasms / surgery
      • Eye Neoplasms / veterinary
      • Female
      • Follow-Up Studies
      • Horse Diseases / radiotherapy
      • Horse Diseases / surgery
      • Horses
      • Iridium Radioisotopes
      • Male
      • Retrospective Studies
      • Sarcoidosis / radiotherapy
      • Sarcoidosis / surgery
      • Sarcoidosis / veterinary
      • Skin Neoplasms / radiotherapy
      • Skin Neoplasms / surgery
      • Skin Neoplasms / veterinary
      • Treatment Outcome

      Citations

      This article has been cited 5 times.
      1. Saba C, Eggleston R, Parks A, Peroni J, Sjoberg E, Rice S, Tyma J, Williams J, Grosenbaugh D, Leard AT. ALVAC-fIL2, a feline interleukin-2 immunomodulator, as a treatment for sarcoids in horses: A pilot study. J Vet Intern Med 2022 May;36(3):1179-1184.
        doi: 10.1111/jvim.16425pubmed: 35416353google scholar: lookup
      2. Giraldo A, Pinard CL, Plattner BL, Dubois MS. Periocular sarcoid with bone invasion in a Thoroughbred mare. Can Vet J 2020 Apr;61(4):415-419.
        pubmed: 32255829
      3. Sypniewska A, Ziółkowska N. Nodular conjunctivitis as a novel ocular manifestation of canine sterile granuloma/pyogranuloma syndrome. BMC Vet Res 2026 Jan 19;22(1):96.
        doi: 10.1186/s12917-026-05289-ypubmed: 41549266google scholar: lookup
      4. Monteiro MM, de Castro ELA, Pereira AJM, Thiesen R, Thiesen RMC, Salvarani FM. BCG Immunotherapy in Equine Sarcoid Treatment: Mechanisms, Clinical Efficacy, and Challenges in Veterinary Oncology. Viruses 2025 Sep 29;17(10).
        doi: 10.3390/v17101322pubmed: 41157593google scholar: lookup
      5. Beermann A, Clottu O, Reif M, Biegel U, Unger L, Koch C. A randomized placebo-controlled double-blinded study comparing oral and subcutaneous administration of mistletoe extract for the treatment of equine sarcoid disease. J Vet Intern Med 2024 May-Jun;38(3):1815-1824.
        doi: 10.1111/jvim.17052pubmed: 38529853google scholar: lookup