Trypanosoma evansi infection in cattle, buffaloes and horses in Indonesia.
Abstract: Cattle, buffaloes and horses in several areas of Indonesia were examined for evidence of infection with Trypanosoma evansi by the microhaematocrit centrifugation technique (MHCT) and an enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to T. evansi. Evidence of infection was found in animals at each sampling site although differences were seen in prevalence rates between sites. Prevalence rates in buffalo were usually higher than in cattle in the same area while in horses they were much lower than in cattle or buffalo. An age-dependent prevalence rate was seen in buffalo and cattle with the highest rates seen in animals older than 2 years. These results concur with the view that T. evansi infection is widespread throughout most of the livestock-producing areas of Indonesia. The apparent lack of any obvious disease owing to T. evansi infection in the sampled animals suggests that a form of stability exists in most endemic areas which serves to ameliorate the effect of T. evansi infection and has an immunological basis linked to the parasite's limited antigenic diversity.
Publication Date: 1991-03-01 PubMed ID: 1858281DOI: 10.1016/0304-4017(91)90121-bGoogle Scholar: Lookup
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- Journal Article
Summary
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The research involves the study of Trypanosoma evansi infection in cattle, buffaloes and horses in Indonesia which indicates the conditions are widespread but show a form of stability due to the parasite’s limited antigenic diversity.
Discussion of the Infection
- This study revolves around the infection caused by Trypanosoma evansi, a protozoan parasite, in cattle, buffalo, and horses in Indonesia. The focus is on the prevalence of this infection and how it varies across different livestock-producing regions of Indonesia and in animals of different ages.
- The techniques employed for investigating the infection were the microhaematocrit centrifugation technique (MHCT) and an enzyme-linked immunosorbent assay (ELISA). These methods were used to detect antibodies to T. evansi, hinting at an active or past infection.
Findings in Different Animals
- The research highlights that the prevalence of the infection varied across animal species and geographical locations. In buffalo, the infection rates were typically higher than in cattle within the same area. Horses, however, demonstrated significantly lower infection rates compared to buffalo and cattle.
- The research also revealed an age-dependent prevalence rate in buffaloes and cattle, with peak infection rates appearing in animals older than two years of age. This could be due to several factors like the increased exposure to vectors over time or age-related changes in the immune system of the animals.
Implication of Findings
- The findings highlight that T. evansi infection is widespread within many livestock-producing regions of Indonesia. It suggests the need for constructive disease management strategies and investment in parasitic control programmes for the welfare of livestock.
- Interestingly, despite the widespread prevalence, the study found no obvious signs of disease in the sampled animals resulting from T. evansi infection. The researchers attribute this to a level of stability existing in these endemic areas that appears to lessen the impact of the T. evansi infection. The reason for this stability may be an immunological response linked to the parasite’s limited antigenic diversity, which possibly facilitates the host’s immune system to effectively control the infection without causing severe disease symptoms.
The implications of this research are significant for the livestock industry in Indonesia. The control of T. evansi infection can aid in better livestock productivity and welfare, ensuring better economic outcomes for livestock farmers.
Cite This Article
APA
Payne RC, Sukanto IP, Djauhari D, Partoutomo S, Wilson AJ, Jones TW, Boid R, Luckins AG.
(1991).
Trypanosoma evansi infection in cattle, buffaloes and horses in Indonesia.
Vet Parasitol, 38(2-3), 109-119.
https://doi.org/10.1016/0304-4017(91)90121-b Publication
Researcher Affiliations
- Research Institute for Veterinary Science, Bogor, West Java, Indonesia.
MeSH Terms
- Animals
- Antibodies, Protozoan / analysis
- Buffaloes
- Cattle
- Enzyme-Linked Immunosorbent Assay / veterinary
- Horse Diseases / parasitology
- Horses
- Indonesia
- Species Specificity
- Trypanosomiasis / diagnosis
- Trypanosomiasis / parasitology
- Trypanosomiasis / veterinary
- Trypanosomiasis, Bovine / diagnosis
- Trypanosomiasis, Bovine / parasitology
Citations
This article has been cited 11 times.- Sharma D, Gupta S, Sethi K, Kumar S, Kumar R. Seroprevalence and immunological characterization of Trypanosoma evansi infection in livestock of four agro-climatic zones of Himachal Pradesh, India.. Trop Anim Health Prod 2022 Jan 15;54(1):60.
- Briggs EM, Warren FSL, Matthews KR, McCulloch R, Otto TD. Application of single-cell transcriptomics to kinetoplastid research.. Parasitology 2021 Sep;148(10):1223-1236.
- Aregawi WG, Agga GE, Abdi RD, Büscher P. Systematic review and meta-analysis on the global distribution, host range, and prevalence of Trypanosoma evansi.. Parasit Vectors 2019 Jan 31;12(1):67.
- Giordani F, Morrison LJ, Rowan TG, DE Koning HP, Barrett MP. The animal trypanosomiases and their chemotherapy: a review.. Parasitology 2016 Dec;143(14):1862-1889.
- Desquesnes M, Dargantes A, Lai DH, Lun ZR, Holzmuller P, Jittapalapong S. Trypanosoma evansi and surra: a review and perspectives on transmission, epidemiology and control, impact, and zoonotic aspects.. Biomed Res Int 2013;2013:321237.
- Desquesnes M, Holzmuller P, Lai DH, Dargantes A, Lun ZR, Jittaplapong S. Trypanosoma evansi and surra: a review and perspectives on origin, history, distribution, taxonomy, morphology, hosts, and pathogenic effects.. Biomed Res Int 2013;2013:194176.
- Adrian MS, Sani RA, Hassan L, Wong MT. Outbreaks of trypanosomiasis and the seroprevalence of T. evansi in a deer breeding centre in Perak, Malaysia.. Trop Anim Health Prod 2010 Feb;42(2):145-50.
- Cheah TS, Sani RA, Chandrawathani P, Bahri S, Dahlan I. Epidemiology of Trypanosoma evansi infection in crossbred dairy cattle in Malaysia.. Trop Anim Health Prod 1999 Feb;31(1):25-31.
- Boid R, Hunter AG, Jones TW, Ross CA, Sutherland D, Luckins AG. Trypanosomosis research at the Centre for Tropical Veterinary Medicine (CTVM) 1970 to 1995.. Trop Anim Health Prod 1996 Feb;28(1):5-22.
- Payne RC, Sukanto IP, Partoutomo S, Sitepu P, Jones TW. Effect of suramin treatment on the productivity of feedlot cattle in a Trypanosoma evansi endemic area of Indonesia.. Trop Anim Health Prod 1994 Feb;26(1):35-6.
- Payne RC, Sukanto IP, Partoutomo S, Jones TW, Luckins AG, Boid R. Efficacy of Cymelarsan in Friesian Holstein calves infected with Trypanosoma evansi.. Trop Anim Health Prod 1994 Nov;26(4):219-26.
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