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American journal of veterinary research2025; 1-11; doi: 10.2460/ajvr.24.11.0328

Ultrasound-guided celiac plexus block increases intestinal motility in normal horses.

Abstract: To describe a technique for ultrasound-guided celiac plexus block in horses and characterize its effect on intestinal motility in healthy horses. Methods: This study was conducted from January 2022 through June 2022. In phase 1 (dye study), an ultrasound-guided technique was optimized, and dye deposition around the celiac plexus branches was evaluated via postmortem dissection in 6 horses. In phase 2 (experimental study), 6 healthy horses were fasted and sedated with 0.6 mg/kg xylazine, IV (experiment 1). After a washout period, the ultrasound-guided celiac plexus block with lidocaine 1% (1.3 mg/kg) was performed after sedation (experiment 2). In both experiments, intestinal motility was recorded via transcutaneous ultrasound before sedation, after sedation (15, 30, and 45 minutes and 1, 2, 3, 4, and 6 hours), and 1 hour after refeeding. Ultrasound video recordings were blinded of horse identity, day, and time; randomly arranged; and scored using a specifically designed motility scoring system. Results: Postmortem dissection confirmed dye deposition over the celiac plexus branches. In phase 2, a significant increase in intestinal motility was detected after the celiac plexus block compared to sedation alone, with a peak between 1 and 3 hours postblock (13.58 ± 2.8 vs 3.75 ± 2.4 at baseline); motility remained increased up to 6 hours. The only side effect observed was a transient hindlimb ataxia in 1 horse. Conclusions: Ultrasound-guided celiac plexus block is feasible and induces an increase in intestinal motility in healthy horses without significant complications. Conclusions: This technique can be considered in multimodal management of colic and paralytic ileus.
Publication Date: 2025-01-21 PubMed ID: 39842103DOI: 10.2460/ajvr.24.11.0328Google Scholar: Lookup
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Summary

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The research article explores the technique of ultrasound-guided celiac plexus block in horses and how it affects intestinal motility. The findings reveal that this method can significantly increase intestinal motility in healthy horses without causing severe complications, suggesting its potential use in the multimodal management of colic and paralytic ileus.

Objective and Methodology

  • This study’s aim was to outline a technique for ultrasound-guided celiac plexus block in horses and outline its effect on intestinal motility in healthy horses.
  • The study was divided into two phases – one focusing on optimizing the technique and evaluating dye deposition around the celiac plexus branches, and the second examining the impact on intestinal motility.
  • The first phase used six horses where post-mortem dissection helped confirm dye deposition.
  • The second phase of the study involved six healthy horses that were fasted and sedated with 0.6 mg/kg xylazine, IV. This was followed by a washout period before performing the ultrasound-guided celiac plexus block.

Findings

  • In the second phase, a significant increase in intestinal motility was observed after applying the celiac plexus block, compared to sedation only. The motility reached its peak between 1 and 3 hours postblock.
  • Motility remained elevated for up to 6 hours, showing that the block has a prolonged effect.
  • The side effects were minimal with only a temporary ataxia or loss of full control of bodily movements observed in one horse.

Conclusion

  • From these results, the researchers concluded that ultrasound-guided celiac plexus block can feasibly be applied and results in an increased activity of the intestines in healthy horses without causing significant complications.
  • The study supports consideration of this technique in multimodal management of colic (severe abdominal pain) and paralytic ileus (a condition affecting the ability of the intestine to contract).

Cite This Article

APA
Delvescovo B, Chevalier JM, Campoy L, Cercone M. (2025). Ultrasound-guided celiac plexus block increases intestinal motility in normal horses. Am J Vet Res, 1-11. https://doi.org/10.2460/ajvr.24.11.0328

Publication

ISSN: 1943-5681
NlmUniqueID: 0375011
Country: United States
Language: English
Pages: 1-11

Researcher Affiliations

Delvescovo, Barbara
    Chevalier, Jacqueline M
      Campoy, Luis
        Cercone, Marta

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