Use of appropriate antimicrobials in wound management.
Abstract: The primary goal of wound management is to achieve a functional closure with minimal scarring. Preventing infection is important to facilitate the healing process. Most simple, uncomplicated wounds do not need systemic antibiotics but benefit from the use of topical antibiotics. Judicious use of antibiotics reduces unnecessary adverse events and helps reduce the development of resistance. Although antibiotics can help reduce infection risk and promote healing, they are not a substitute for good local wound care, in particular irrigation and surgical débridement. This article reviews the role of antibiotics in emergency department wound management.
Publication Date: 2007-04-03 PubMed ID: 17400079DOI: 10.1016/j.emc.2007.01.007Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research emphasizes the judicious use of antimicrobials in wound management of horses, pointing out that antimicrobials should supplement general wound care methods such as lavage and drainage to promote healing. Bacterial resistance and its implications for wound care, including necessary veterinary precautions for personal hygiene, are also discussed in detail.
Role of Antimicrobials in Wound Management
- The paper urges a proper understanding of the place of antimicrobial medication in the general care of wounds in horses. Antimicrobials should not replace other core wound care practices such as lavage (cleaning a wound or during surgery) or drainage but rather supplement them to aid healing.
- The use of these drugs should be based on the results from diagnostics tests and the professional assessment of the veterinarian as indiscriminate use can lead to bacterial resistance, a significant issue in healthcare.
Bacterial Contamination and Infection
- Alluding to the similarity between the organisms that infect humans and horses, the paper emphasizes the importance of maintaining personal hygiene and protection when caring for equine patients to prevent zoonotic transmission (diseases spread between animals and humans).
- Wound management also necessitates proper disposal of used bandage materials and protective clothing because the level of microbial contamination in infected wounds can be considerably higher than in other everyday veterinary activities.
Bacterial Resistance
- The concept of bacterial resistance, a natural survival mechanism adopted by bacteria in response to the overuse of antibiotics, is discussed as a key clinical concern for both vets and physicians.
- The paper acknowledges the controversies and limited understanding surrounding bacterial resistance. However, it underscores its relevance to veterinary practice and wound management in horses.
- The research calls for recognition of bacterial resistance as a continued clinical consideration in view of its significant role over the last six to seven decades.
Biosecurity and Judicious Antimicrobial Use
- Given the zoonotic nature of antimicrobial resistance, veterinarians are urged to implement biosecurity procedures to protect themselves, other people interacting with pathogens, and the horse patients.
- The paper concludes by reiterating the importance of judicious and targeted use of antimicrobials in managing wound infections. Applying appropriate principles in antimicrobial use is crucial for the well-being and recovery of animal patients.
Cite This Article
APA
Nakamura Y, Daya M.
(2007).
Use of appropriate antimicrobials in wound management.
Emerg Med Clin North Am, 25(1), 159-176.
https://doi.org/10.1016/j.emc.2007.01.007 Publication
Researcher Affiliations
- Department of Emergency Medicine, Oregon Health & Science University, 2730 NW Pettygrove Street, Portland, OR 97210-2449, USA.
MeSH Terms
- Adult
- Animals
- Anti-Bacterial Agents / therapeutic use
- Bites and Stings / drug therapy
- Bites and Stings / etiology
- Bites and Stings / microbiology
- Cats
- Child, Preschool
- Dogs
- Emergency Service, Hospital
- Female
- Humans
- Male
- Risk Factors
- Therapeutic Irrigation / methods
- Wound Infection / etiology
- Wound Infection / microbiology
- Wound Infection / prevention & control
- Wounds and Injuries / classification
- Wounds and Injuries / drug therapy
- Wounds and Injuries / therapy
References
This article includes 75 references
Citations
This article has been cited 13 times.- Appelbaum RD, Farrell MS, Gelbard RB, Hoth JJ, Jawa RS, Kirsch JM, Mandell S, Nohra EA, Rinderknecht T, Rowell S, Cuschieri J, Stein DM. Antibiotic prophylaxis in injury: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surg Acute Care Open 2024;9(1):e001304.
- Styková E, Nemcová R, Maďar M, Bujňáková D, Mucha R, Gancarčíková S, Requena Domenech F. Antibiofilm Activity of Weissella spp. and Bacillus coagulans Isolated from Equine Skin against Staphylococcus aureus. Life (Basel) 2022 Dec 17;12(12).
- Esposito S, Sgarzani R, Bianchini S, Monaco S, Nicoletti L, Rigotti E, Di Pietro M, Opri R, Caminiti C, Ciccia M, Conti G, Donà D, Giuffré M, La Grutta S, Lancella L, Lima M, Lo Vecchio A, Pelizzo G, Piacentini G, Pietrasanta C, Puntoni M, Simonini A, Venturini E, Staiano A, Principi N, On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group. Surgical Antimicrobial Prophylaxis in Pediatric Patients Undergoing Plastic Surgery: A RAND/UCLA Appropriateness Method Consensus Study. Antibiotics (Basel) 2022 Apr 11;11(4).
- Fayez MS, Hakim TA, Agwa MM, Abdelmoteleb M, Aly RG, Montaser NN, Abdelsattar AS, Rezk N, El-Shibiny A. Topically Applied Bacteriophage to Control Multi-Drug Resistant Klebsiella pneumoniae Infected Wound in a Rat Model. Antibiotics (Basel) 2021 Aug 27;10(9).
- Fijan S, Frauwallner A, Langerholc T, Krebs B, Ter Haar Née Younes JA, Heschl A, Mičetić Turk D, Rogelj I. Efficacy of Using Probiotics with Antagonistic Activity against Pathogens of Wound Infections: An Integrative Review of Literature. Biomed Res Int 2019;2019:7585486.
- Beam JW, Buckley B, Holcomb WR, Ciocca M. National Athletic Trainers' Association Position Statement: Management of Acute Skin Trauma. J Athl Train 2016 Dec;51(12):1053-1070.
- Sevgi M, Toklu A, Vecchio D, Hamblin MR. Topical antimicrobials for burn infections - an update. Recent Pat Antiinfect Drug Discov 2013 Dec;8(3):161-97.
- Ghafouri HB, Bagheri-Behzad B, Yasinzadeh MR, Modirian E, Divsalar D, Farahmand S. Prophylactic Antibiotic Therapy in Contaminated Traumatic Wounds: Two Days versus Five Days Treatment. Bioimpacts 2012;2(1):33-7.
- Ong S, Moran GJ, Krishnadasan A, Talan DA. Antibiotic prescribing practices of emergency physicians and patient expectations for uncomplicated lacerations. West J Emerg Med 2011 Nov;12(4):375-80.
- Medel N, Panchal N, Ellis E. Postoperative care of the facial laceration. Craniomaxillofac Trauma Reconstr 2010 Dec;3(4):189-200.
- Kramer A, Assadian O, Frank M, Bender C, Hinz P. Prevention of post-operative infections after surgical treatment of bite wounds. GMS Krankenhhyg Interdiszip 2010 Sep 21;5(2).
- Patil PD, Panchabhai TS, Galwankar SC. Managing human bites. J Emerg Trauma Shock 2009 Sep;2(3):186-90.
- Bearden DT, Allen GP, Christensen JM. Comparative in vitro activities of topical wound care products against community-associated methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 2008 Oct;62(4):769-72.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
