Abstract: Artificial intelligence (AI) is increasingly used to enhance electrocardiogram (ECG) interpretation in human medicine. In equine athletes, exercise-associated arrhythmias are common and linked to sudden cardiac death at rates higher than in humans. However, ECG interpretation in horses remains time-consuming and subjective, with the clinical relevance of mild rhythm disturbances often unclear. Objective: Evaluate the application of AI to ECG interpretation for arrhythmia detection, with emphasis on current and potential use in athletic species, particularly horses. Methods: About 17 studies were included: 13 involving humans, 3 in horses, and 1 in dogs. Methods: A scoping review of relevant, peer-reviewed studies published between 2000 and 2024 was conducted to identify research applying AI to ECG interpretation for arrhythmia detection. Studies were assessed for species, AI model type, diagnostic accuracy, and relevance to ECGs recorded during exercise. Primary outcomes included arrhythmia detection performance and applicability to veterinary medicine. Results: Deep learning models, including convolutional neural networks, achieved accuracies ranging from 79.4% to 98.6% in studies of humans. Research in horses showed encouraging results using restitution analysis and transfer learning approaches. However, small sample sizes and species-specific ECG morphology remain major limitations to broader application in veterinary medicine. Conclusions: Artificial intelligence holds promise for enhancing the accuracy and efficiency of arrhythmia detection in ECGs of equine athletes. Development of species-specific algorithms may facilitate real-time monitoring of cardiac function during exercise, supporting improved cardiovascular assessment in athletic horses.
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Overview
This research article reviews the use of artificial intelligence (AI) for detecting cardiac rhythm disturbances, specifically arrhythmias, in athletes by interpreting electrocardiograms (ECGs).
It focuses on comparing AI applications in human medicine with potential uses in veterinary medicine, especially in athletic horses, where arrhythmias are common and linked to sudden cardiac death.
Introduction and Background
Artificial intelligence is increasingly integrated into medical diagnostics to improve interpretation accuracy and efficiency, especially for ECGs, which are critical for identifying heart rhythm disturbances.
In human athletes, AI has already been applied with promising results for automated arrhythmia detection, aiding early diagnosis and treatment.
In equine athletes (horses), arrhythmias during exercise are quite common and pose a higher risk of sudden cardiac death compared to humans.
Despite this, interpreting equine ECGs remains a challenge due to:
The subjective and time-consuming nature of manual ECG interpretation
The uncertain clinical significance of mild rhythm disturbances
Species-specific differences in ECG morphology compared to humans
Objective
The main goal was to evaluate how AI has been applied to improve ECG interpretation and arrhythmia detection, with a focus on its current and potential use in athletic species like horses.
Methods
A scoping review was conducted of peer-reviewed studies published from 2000 to 2024.
Relevant studies involving AI algorithms for ECG arrhythmia detection were identified.
A total of 17 studies were included in the review:
13 on humans
3 on horses
1 on dogs
Each study was evaluated based on several criteria:
Species studied (human, equine, canine)
Type of AI model used
Diagnostic accuracy achieved
Relevance and applicability to ECGs recorded during exercise
Primary outcomes focused on arrhythmia detection performance and potential veterinary applications.
Results
AI models, especially deep learning techniques like convolutional neural networks (CNNs), demonstrated high accuracy in human studies covering a wide range of arrhythmias:
Accuracy ranged from 79.4% up to 98.6%
These models facilitated efficient and objective ECG interpretation in humans
In horses, preliminary research showed promising results using two main AI approaches:
Restitution analysis – studying changes in heartbeat properties over time
Transfer learning – leveraging AI models pre-trained on human data adapted to equine ECGs
Despite these advances, there were significant limitations for veterinary application:
Small sample sizes in equine studies limited generalizability
Distinct ECG morphology of horses differed markedly from humans, complicating direct application of human AI models
Conclusions and Implications
Artificial intelligence shows significant promise to enhance detection of cardiac rhythm disturbances in equine athletes by providing rapid, objective, and accurate ECG analysis.
Developing species-specific AI algorithms tailored to equine ECG characteristics is necessary to overcome current limitations and improve diagnostic accuracy.
Such advances could enable real-time monitoring of cardiac function during exercise, supporting better cardiovascular health assessment and management in athletic horses.
In summary, adapting AI technology from human medicine has the potential to revolutionize cardiac care in veterinary sports medicine, enhancing both diagnosis and prevention of sudden cardiac events in horses.
Cite This Article
APA
Kapusniak A, Lara NM, Hitchens PL, Bailey S, Nath L, Franklin S.
(2025).
Use of Artificial Intelligence to Detect Cardiac Rhythm Disturbances in Athletes: A Scoping Review.
J Vet Intern Med, 39(6), e70257.
https://doi.org/10.1111/jvim.70257
Colgate VA, EASDiR Working Group. IFHA Global Summit on Equine Safety and Technology: Reducing the Risk of Exercise Associated Sudden Death. 57, no. 2 (2025): 296–302.
Maron BJ, Doerer JJ, Haas TS, Tierney DM, Mueller FO. Sudden Deaths in Young Competitive Athletes: Analysis of 1866 Deaths in the United States, 1980–2006. Circulation 119 (2009): 1085–1092.
Attia ZI, Harmon DM, Behr ER, Friedman PA. Application of Artificial Intelligence to the Electrocardiogram. European Heart Journal 42 (2021): 4717–4730.
Feeny AK, Chung MK, Madabhushi A. Artificial Intelligence and Machine Learning in Arrhythmias and Cardiac Electrophysiology. Circulation: Arrhythmia and Electrophysiology 13 (2020): e007952.
Castillo‐Atoche A, Caamal‐Herrera K, Atoche‐Enseñat R. Energy Efficient Framework for a AIoT Cardiac Arrhythmia Detection System Wearable During Sport. Applied Sciences 12 (2022): 2716.
Zhuang J, Sun J, Yuan G. Arrhythmia Diagnosis of Young Martial Arts Athletes Based on Deep Learning for Smart Medical Care. Neural Computing and Applications 35 (2023): 14641–14652.
Attia Z I, Noseworthy P A, Lopez‐Jimenez F. An Artificial Intelligence‐Enabled ECG Algorithm for the Identification of Patients With Atrial Fibrillation During Sinus Rhythm: A Retrospective Analysis of Outcome Prediction. Lancet 394 (2019): 861–867.
Kolk M Z, Ruipérez‐Campillo S, Wilde A A, Knops R E, Narayan S M, Tjong F V. Prediction of Sudden Cardiac Death Using Artificial Intelligence: Current Status and Future Directions. Heart Rhythm 22 (2025): 756–766.
Camm N J, Redzeppagc S, Raufi A, Banach M, Oterino A. Revolutionizing Cardiac Diagnosis: An AI Algorithm for Heart Abnormality Detection in Medical Imaging—A Review of Current and Emerging Techniques. Clinical Cardiology and Cardiovascular Interventions 6, no. 2 (2023): 304.
Van Steenkiste G., “Equine Electrocardiography Revisited: 12‐Lead Recording, Vectorcardiography and the Power of Machine Intelligence,” 2020. Ghent University.
Meyling H, Ter Borg H. The Conducting System of the Heart in Hoofed Animals. Cornell Veterinarian 47 (1957): 419–447.
Van Steenkiste G, van Loon G, Crevecoeur G. Transfer Learning in ECG Classification From Human to Horse Using a Novel Parallel Neural Network Architecture. Scientific Reports 10 (2020): 186.
Tricco A C, Lillie E, Zarin W. PRISMA Extension for Scoping Reviews (PRISMA‐ScR): Checklist and Explanation. Annals of Internal Medicine 169 (2018): 467–473.
Maron B J, Pelliccia A. The Heart of Trained Athletes: Cardiac Remodeling and the Risks of Sports, Including Sudden Death. Circulation 114 (2006): 1633–1644.
Covidence Systematic Review Software (Veritas Health Innovation, 2024).
Adetiba E, Iweanya V C, Popoola S I, Adetiba J N, Menon C. Automated Detection of Heart Defects in Athletes Based on Electrocardiography and Artificial Neural Network. Cogent Engineering 4 (2017): 1411220.
Ji W, Zhu D. ECG Classification Exercise Health Analysis Algorithm Based on GRU and Convolutional Neural Network. IEEE Access 12 (2024): 59842–59850.
Munoz‐Macho A, Dominguez‐Morales M J, Sevillano‐Ramos J L. Analyzing ECG Signals in Professional Football Players Using Machine Learning Techniques. Heliyon 10 (2024): e26789.
Jo Y‐Y, Cho Y, Lee S Y. Explainable Artificial Intelligence to Detect Atrial Fibrillation Using Electrocardiogram. International Journal of Cardiology 328 (2021): 104–110.
Kumar A, Kumar S A, Dutt V, Shitharth S, Tripathi E. IoT Based Arrhythmia Classification Using the Enhanced Hunt Optimization‐Based Deep Learning. Expert Systems 40 (2023): e13298.
Wang T, Qin Y. A Novel Multi‐Scale Convolutional Network With Attention‐Based Bidirectional Gated Recurrent Unit for Atrial Fibrillation Discrimination. Biocybernetics and Biomedical Engineering 41 (2021): 445–455.
Flanders W H, Moïse N S, Otani N F. Use of Machine Learning and Poincaré Density Grid in the Diagnosis of Sinus Node Dysfunction Caused by Sinoatrial Conduction Block in Dogs. Journal of Veterinary Internal Medicine 38 (2024): 1305–1324.
Bellfield R A, Ortega‐Martorell S, Lip G Y, Oxborough D, Olier I. The Athlete's Heart and Machine Learning: A Review of Current Implementations and Gaps for Future Research. Journal of Cardiovascular Development and Disease 9 (2022): 382.
Chang A C. Primary Prevention of Sudden Cardiac Death of the Young Athlete: The Controversy About the Screening Electrocardiogram and Its Innovative Artificial Intelligence Solution. Pediatric Cardiology 33 (2012): 428–433.
Palermi S, Vecchiato M, Saglietto A. Unlocking the Potential of Artificial Intelligence in Sports Cardiology: Does it Have a Role in Evaluating Athlete's Heart?. European Journal of Preventive Cardiology 31 (2024): 470–482.
Vetter T R, Schober P, Mascha E J. Diagnostic Testing and Decision‐Making: Beauty Is Not Just in the Eye of the Beholder. Anesthesia & Analgesia 127 (2018): 1085–1091.
Exeter D J, Elley C R, Fulcher M L, Lee A C, Drezner J A, Asif I M. Standardised Criteria Improve Accuracy of ECG Interpretation in Competitive Athletes: A Randomised Controlled Trial. British Journal of Sports Medicine 48 (2014): 1167–1171.
Trevethan R. Sensitivity, Specificity, and Predictive Values: Foundations, Pliabilities, and Pitfalls in Research and Practice. Frontiers in Public Health 5 (2017): 307.
Hajian‐Tilaki K. The Choice of Methods in Determining the Optimal Cut‐Off Value for Quantitative Diagnostic Test Evaluation. Statistical Methods in Medical Research 27 (2018): 2374–2383.
Navas de Solis C, Green C M, Sides R H, Bayly W M. Arrhythmias in Thoroughbreds During and After Treadmill and Racetrack Exercise. Journal of Equine Veterinary Science 42 (2016): 19–24.
Allen K, Young L, Franklin S. Evaluation of Heart Rate and Rhythm During Exercise. Equine Veterinary Education 28 (2016): 99–112.