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Use of contrast media in computed tomography and magnetic resonance imaging in horses: Techniques, adverse events and opportunities.
Abstract: The use of contrast media in computed tomography (CT) and magnetic resonance imaging (MRI) is increasing in horses. These contrast-enhanced imaging techniques provide improved tissue delineation and evaluation, thereby expanding diagnostic capabilities. While generally considered safe, not all contrast media exhibit the same safety profiles. The safety of contrast media use and descriptions of adverse events occurring in horses are sparsely reported. This review summarises the reported evidence of contrast media use and adverse events that occur in horses, with added contribution from other veterinary species and studies in man for comparison. This comprehensive data set empowers equine clinicians to develop use and monitoring strategies when working with contrast media. Finally, it summarises the current state-of-the-art and highlights the potential applications of contrast-enhanced CT and MRI for assessment of diseased or injured equine tissues, as well as (patho)physiological processes.
© 2017 EVJ Ltd.
Publication Date: 2017-05-22 PubMed ID: 28407291DOI: 10.1111/evj.12689Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
- Adverse Effects
- Clinical Study
- Comparative Study
- Computed Tomography
- Diagnosis
- Diagnostic Imaging
- Diagnostic Technique
- Disease Diagnosis
- Equine Health
- Horses
- Imaging Techniques
- Magnetic Resonance Imaging
- Pathophysiology
- Radiology
- Species Comparison
- Treatment
- Veterinary Medicine
- Veterinary Practice
- Veterinary Research
- Veterinary Science
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research article discusses the increasing use of contrast media in CT and MRI scans for horses, detailing the techniques, potential dangers, and opportunities it provides. The paper reviews existing reports of contrast media usage and adverse events in horses, using data from other animal species and humans for comparison.
Techniques
- The paper explores the various techniques for using contrast media in CT and MRI imaging. These range from simple intravenous injection to more complex approaches like selective arterial or joint cavity injection. The choice of technique might depend on the clinical need, the specific area of interest, and the technical capabilities of the imaging device in use.
Adverse Events
- The article notes that the safety profiles of contrast media are not all the same. The review delves into the adverse events that can occur when contrast media are used in imaging horses. It highlights potential mild adverse reactions such as vomiting, fever, or itchiness, but also warns of severe, although rare, reactions like anaphylactic shock.
- It also brings to light that, despite some adverse events being reported, most cases of contrast media usage in horses have been considered safe.
Opportunities
- The paper emphasizes that the use of contrast media considerably improves the imaging of soft tissue, enhancing the diagnostic capabilities for a variety of diseases and injuries in horses, thereby providing more opportunities for accurate diagnosis and treatment planning.
- It furthermore encourages equine clinicians to leverage the compiled data to develop strategies for monitoring and managing horses undergoing contrast-enhanced CT and MRI imaging.
- The paper concludes by summarizing the state-of-the-art in contrast-enhanced imaging and outlining potential applications, such as delineating injured or diseased tissues and tracking (patho)physiological processes, among others.
Cite This Article
APA
Nelson BB, Goodrich LR, Barrett MF, Grinstaff MW, Kawcak CE.
(2017).
Use of contrast media in computed tomography and magnetic resonance imaging in horses: Techniques, adverse events and opportunities.
Equine Vet J, 49(4), 410-424.
https://doi.org/10.1111/evj.12689 Publication
Researcher Affiliations
- Gail Holmes Equine Orthopaedic Research Center, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
- Gail Holmes Equine Orthopaedic Research Center, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
- Gail Holmes Equine Orthopaedic Research Center, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
- Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
- Departments of Biomedical Engineering, Chemistry, Materials Science & Engineering and Medicine, Boston University, Boston, Massachusetts, USA.
- Gail Holmes Equine Orthopaedic Research Center, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
MeSH Terms
- Animals
- Contrast Media / administration & dosage
- Female
- Horses
- Magnetic Resonance Imaging / methods
- Magnetic Resonance Imaging / veterinary
- Male
- Tomography, X-Ray Computed / methods
- Tomography, X-Ray Computed / veterinary
Citations
This article has been cited 15 times.- Thampi P, Seabaugh KA, Pezzanite LM, Chu CR, Phillips JN, Grieger JC, McIlwraith CW, Samulski RJ, Goodrich LR. A pilot study to determine the optimal dose of scAAVIL-1ra in a large animal model of post-traumatic osteoarthritis. Gene Ther 2023 Sep 11;.
- Thampi P, Samulski RJ, Grieger JC, Phillips JN, McIlwraith CW, Goodrich LR. Gene therapy approaches for equine osteoarthritis. Front Vet Sci 2022;9:962898.
- Honkanen MKM, Mohammadi A, Te Moller NCR, Ebrahimi M, Xu W, Plomp S, Pouran B, Lehto VP, Brommer H, van Weeren PR, Korhonen RK, Töyräs J, Mäkelä JTA. Dual-contrast micro-CT enables cartilage lesion detection and tissue condition evaluation ex vivo. Equine Vet J 2023 Mar;55(2):315-324.
- Nelson BB, Stewart RC, Kawcak CE, Freedman JD, Patwa AN, Snyder BD, Goodrich LR, Grinstaff MW. Quantitative Evaluation of Equine Articular Cartilage Using Cationic Contrast-Enhanced Computed Tomography. Cartilage 2021 Apr;12(2):211-221.
- Shi B, Huang H. Computational technology for nasal cartilage-related clinical research and application. Int J Oral Sci 2020 Jul 27;12(1):21.
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- van Zadelhoff C, Schwarz T, Smith S, Engerand A, Taylor S. Identification of Naturally Occurring Cartilage Damage in the Equine Distal Interphalangeal Joint Using Low-Field Magnetic Resonance Imaging and Magnetic Resonance Arthrography. Front Vet Sci 2019;6:508.
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- Qian H, Qin X, Xing G, Shi C, Zhang L. Comparison of the efficacy and characteristics of metallic foreign body extraction by incision surgery and x-ray guided forceps after body-surface projection positioning: A STROBE-compliant article. Medicine (Baltimore) 2018 Aug;97(35):e12116.
- Sun J, Li Z. Study on the Correlation between Barium Radiography and Pulmonary Infection rate in the Evaluation of Swallowing Function. Clinics (Sao Paulo) 2018;73:e182.
- Frey K, Perlini M, Reed R. Time Attenuation Curves for Equine Intravenous Contrast Enhanced Skull CT Using the Medial Saphenous and Cephalic Veins. Vet Radiol Ultrasound 2026 Jan;67(1):e70115.
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- Witkowska-Piłaszewicz O, Malin K, Dąbrowska I, Grzędzicka J, Ostaszewski P, Carter C. Immunology of Physical Exercise: Is Equus caballus an Appropriate Animal Model for Human Athletes?. Int J Mol Sci 2024 May 10;25(10).
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