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Journal of the American Veterinary Medical Association2003; 223(11); 1617-1599; doi: 10.2460/javma.2003.223.1617

Use of high-resolution ultrasound as a diagnostic tool in veterinary ophthalmology.

Abstract: The recent development of a 20-MHz, high-frequency ultrasound probe has allowed tissue to be visualized at resolutions of 20 to 80 microm, which is similar to a low-power histologic view. This high degree of resolution, however, limits tissue penetration to 5 to 10 mm, which is ideal for examination of the anterior segment of the eye. The detail provided by high-resolution ultrasound readily permits the clinician to distinguish between various anterior segment entities that may appear similar but are treated quite differently, such as anterior uveal tumors, iridociliary cysts, and iris bombé. High-frequency ultrasound is also a valuable aid in creating a surgical plan for treatment of ocular disorders in which the cornea is opaque, such as feline corneal sequestrum and tumor invasion into the cornea. Other applications of this technology include elucidation of the pathogenesis of glaucoma in veterinary patients and evaluation of regions of the lens that are difficult to examine directly.
Publication Date: 2003-12-11 PubMed ID: 14664449DOI: 10.2460/javma.2003.223.1617Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research studies the application of a high-frequency ultrasound probe in veterinary ophthalmology. The tool can visualize tissue at a high resolution and is particularly useful for examining forward sections of the eye and aiding in surgical planning for ocular disorders.

High-Frequency Ultrasound in Veterinary Ophthalmology

  • The research presents an application of a novel 20-MHz ultrasound tool in the field of veterinary ophthalmology. This high-resolution probe can visualize tissue at fine details ranging between 20 to 80 microm, similar to a low-power histological view. However, high resolution constrains tissue penetration to 5 to 10mm, which is ideal for examining the eye’s anterior segment.
  • The high-resolution imagery delivered by ultrasound enables clinicians to differentiate between various anterior segment cases that may seem alike but require different treatments. Typical examples include anterior uveal tumors, iridociliary cysts, and iris bombs.

Ultrasound in Surgical Planning and Other Applications

  • Another notable application of this technology is aiding surgical planning for treating ocular disorders where the cornea is cloudy. These conditions can include feline corneal sequestrum and tumor intrusion into the cornea. Ultrasonography can help in creating a precise surgical plan for these disorders.
  • Other possible uses of this technology include understanding the pathogenesis of diseases like glaucoma in veterinary patients and assessing lens regions that are challenging to inspect directly. Thus, the versatility of high-resolution ultrasound makes it promising for extensive use in veterinary ophthalmology.

Cite This Article

APA
Bentley E, Miller PE, Diehl KA. (2003). Use of high-resolution ultrasound as a diagnostic tool in veterinary ophthalmology. J Am Vet Med Assoc, 223(11), 1617-1599. https://doi.org/10.2460/javma.2003.223.1617

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 223
Issue: 11
Pages: 1617-1599

Researcher Affiliations

Bentley, Ellison
  • Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706-1102, USA.
Miller, Paul E
    Diehl, Kathryn A

      MeSH Terms

      • Animals
      • Cat Diseases / diagnostic imaging
      • Cats
      • Diagnostic Techniques, Ophthalmological / instrumentation
      • Diagnostic Techniques, Ophthalmological / veterinary
      • Dog Diseases / diagnostic imaging
      • Dogs
      • Eye Diseases / diagnostic imaging
      • Eye Diseases / veterinary
      • Female
      • Glaucoma / diagnostic imaging
      • Glaucoma / veterinary
      • Horse Diseases / diagnostic imaging
      • Horses
      • Male
      • Sensitivity and Specificity
      • Treatment Outcome
      • Ultrasonography / instrumentation
      • Ultrasonography / methods
      • Ultrasonography / veterinary
      • Uveal Diseases / diagnostic imaging
      • Uveal Diseases / veterinary

      Citations

      This article has been cited 19 times.
      1. Ostendarp C, Barton AK. Intraocular Tumors in Horses: Diagnosis, Tumor Classification, Oncologic Assessment and Therapy. Vet Sci 2025 Oct 17;12(10).
        doi: 10.3390/vetsci12101006pubmed: 41150147google scholar: lookup
      2. Kim D, Jung JS, Hwang J, Park J, Kwon M, Yong J, Yoon H, Park KM. Comparative analysis of iridocorneal angle in cats and dogs using ultrasound biomicroscopy: implications for glaucoma prevalence. BMC Vet Res 2025 Mar 19;21(1):181.
        doi: 10.1186/s12917-025-04648-5pubmed: 40102853google scholar: lookup
      3. Kim D, Kwon H, Hwang J, Jung JS, Park KM. An in-depth review on utilizing ultrasound biomicroscopy for assessing the iridocorneal angle and ciliary body in canines. Front Vet Sci 2025;12:1501405.
        doi: 10.3389/fvets.2025.1501405pubmed: 40078210google scholar: lookup
      4. Kim D, Kwon H, Hwang J, Jung JS, Park KM. Quantitative analysis of iridocorneal angle and ciliary cleft structures in canine eyes using ultrasound biomicroscopy. Front Vet Sci 2024;11:1476746.
        doi: 10.3389/fvets.2024.1476746pubmed: 39691378google scholar: lookup
      5. Holz N, Kowalska ME, Pot SA, Rampazzo A. Interexaminer agreement of gonioscopy examinations in dogs using the European College of Veterinary Ophthalmologists Hereditary Eye Diseases grading scheme. Vet Ophthalmol 2026 Jan;29(1):e13292.
        doi: 10.1111/vop.13292pubmed: 39482043google scholar: lookup
      6. Kim D, Goh YS, Kim H, Park SE, Hwang J, Kang N, Jung JS, Park KM. Evaluation of ciliary cleft changes after phacoemulsification using ultrasound biomicroscopy in dogs with cataracts. Front Vet Sci 2023;10:1247127.
        doi: 10.3389/fvets.2023.1247127pubmed: 38033645google scholar: lookup
      7. Kashani-Carver A, Turner G, Cáliz GE, Salih A, Jordan C, Cebrian P, Lowe R. Diagnosis, management, and outcome of an intralenticular foreign body in a dog: A case report. Open Vet J 2023 Oct;13(10):1379-1384.
        doi: 10.5455/OVJ.2023.v13.i10.18pubmed: 38027412google scholar: lookup
      8. Wafy MN, Hassan EA, Ahmed KA, Aboelmaaty AM, Abu-Seida AM. Ultrasonographic and histopathologic features associated with common ocular diseases in donkeys (Equus asinus). Vet Res Commun 2023 Sep;47(3):1479-1491.
        doi: 10.1007/s11259-023-10102-4pubmed: 36941479google scholar: lookup
      9. Knickelbein KE, Lassaline ME, Kim S, Thomasy SM. Ultrasound biomicroscopy of the equine iridocorneal angle. Equine Vet J 2022 Nov;54(6):1153-1158.
        doi: 10.1111/evj.13585pubmed: 35568989google scholar: lookup
      10. Ivan D, Ohlerth S, Richter H, Verdino D, Rampazzo A, Pot S. 3T high-resolution magnetic resonance imaging, conventional ultrasonography and ultrasound biomicroscopy of the normal canine eye. BMC Vet Res 2022 Feb 10;18(1):67.
        doi: 10.1186/s12917-021-03108-0pubmed: 35144606google scholar: lookup
      11. Knickelbein KE, Lassaline ME, Kim S, Scharbrough MS, Thomasy SM. Corneal thickness and anterior chamber depth of the normal adult horse as measured by ultrasound biomicroscopy. Vet Ophthalmol 2022 May;25 Suppl 1(Suppl 1):17-24.
        doi: 10.1111/vop.12971pubmed: 35084084google scholar: lookup
      12. Telle MR, Snyder KC, Oikawa K, Nilles JP, Gehrke S, Teixeira LBC, Kiland JA, Huang A, McLellan GJ. Development and validation of methods to visualize conventional aqueous outflow pathways in canine primary angle closure glaucoma. Vet Ophthalmol 2022 May;25 Suppl 1(Suppl 1):84-95.
        doi: 10.1111/vop.12943pubmed: 34581493google scholar: lookup
      13. Szczerkowska KI, Petrezselyova S, Lindovsky J, Palkova M, Dvorak J, Makovicky P, Fang M, Jiang C, Chen L, Shi M, Liu X, Zhang J, Kubik-Zahorodna A, Schuster B, Beck IM, Novosadova V, Prochazka J, Sedlacek R. Myopia disease mouse models: a missense point mutation (S673G) and a protein-truncating mutation of the Zfp644 mimic human disease phenotype. Cell Biosci 2019;9:21.
        doi: 10.1186/s13578-019-0280-4pubmed: 30834109google scholar: lookup
      14. Gialletti R, Marchegiani A, Valeriani T, Nannarone S, Beccati F, Fruganti A, Laus F. A survey of ocular ultrasound abnormalities in horse: 145 cases. J Ultrasound 2018 Mar;21(1):53-59.
        doi: 10.1007/s40477-018-0284-7pubmed: 29492841google scholar: lookup
      15. El-Tookhy O, Tharwat M. Clinical and ultrasonographic findings of some ocular conditions in sheep and goats. Open Vet J 2013;3(1):11-6.
        pubmed: 26623306
      16. Hasegawa T, Kawata M, Ota M. Ultrasound biomicroscopic findings of the iridocorneal angle in live healthy and glaucomatous dogs. J Vet Med Sci 2016 Jan;77(12):1625-31.
        doi: 10.1292/jvms.15-0311pubmed: 26212256google scholar: lookup
      17. Greco A, Mancini M, Gargiulo S, Gramanzini M, Claudio PP, Brunetti A, Salvatore M. Ultrasound biomicroscopy in small animal research: applications in molecular and preclinical imaging. J Biomed Biotechnol 2012;2012:519238.
        doi: 10.1155/2012/519238pubmed: 22163379google scholar: lookup
      18. Gomes FE, Bentley E, Lin TL, McLellan GJ. Effects of unilateral topical administration of 0.5% tropicamide on anterior segment morphology and intraocular pressure in normal cats and cats with primary congenital glaucoma. Vet Ophthalmol 2011 Sep;14 Suppl 1(Suppl 1):75-83.
      19. Hartley C. Treatment of corneal ulcers: when is surgery indicated?. J Feline Med Surg 2010 May;12(5):398-405.
        doi: 10.1016/j.jfms.2010.03.013pubmed: 20417900google scholar: lookup