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Home / Equine Research Bank / J Vet Intern Med / Use of Renal Replacement Therapy in a Neonatal Foal with Pos...
Journal of veterinary internal medicine2017; 31(2); 593-597; doi: 10.1111/jvim.14665

Use of Renal Replacement Therapy in a Neonatal Foal with Postresuscitation Acute Renal Failure.

Abstract: A newborn foal was presented because it was unresponsive and in cardiopulmonary arrest. Aggressive cardiopulmonary cerebral resuscitation was administered to the foal, which revived the foal; however, acute renal failure developed. Fluid retention and azotemia occurred although the foal was alert and able to suckle. A 6-hour renal replacement therapy session using hemodiafiltration and a continuous renal replacement therapy machine was administered to the foal at 3 days of age which lowered the foal's azotemia and facilitated removal of some of the excess body fluid. Despite therapy, the foal developed pulmonary edema and was euthanized. Although the foal in this case did not survive, this report highlights the possibility of developing postresuscitation complications such as acute renal failure and describes the use of renal replacement therapy using hemodiafiltration as a viable option in neonatal foals with acute kidney injury.
Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.
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Publication Date: 2017-02-12 PubMed ID: 28190272PubMed Central: PMC5354042DOI: 10.1111/jvim.14665Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research paper discusses the implementing of renal replacement therapy for the treatment of acute renal failure in a newborn foal who had undergone cardiopulmonary resuscitation. Despite the therapy administered and improvements in some conditions, the foal didn’t survive, highlighting the possible post-resuscitation complications.

Resuscitation and Diagnosis

  • The case began with a neonatal foal that was unresponsive and in a state of cardiopulmonary arrest.
  • The medical team administered aggressive cardiopulmonary cerebral resuscitation to bring the foal back to consciousness.
  • Despite the resuscitation process proving successful initially, the foal later developed acute renal failure.
  • Clear symptoms of the renal failure were fluid retention and azotemia (an excess level of nitrogen compounds in the blood), even though the foal was alert and demonstrated natural suckling behavior.

Treatment and Outcome

  • The team decided to implement renal replacement therapy. The intervention involved hemodiafiltration and the use of a continuous renal replacement therapy machine.
  • The therapy was instituted when the foal was just three days old, and was carried out over a span of a six-hour session.
  • The renal therapy successfully lowered the foal’s azotemia and aided in removing some of the excess body fluid.
  • However, despite these improvements, the foal later developed pulmonary edema (a condition caused by excess fluid in the lungs).
  • Given the critical condition and suffering of the foal, the team decided to euthanize it.

Significance and Future Implications

  • Although the foal in this study did not survive the post-resuscitation complications, the study does provide a valuable look into the potential complications that can arise in neonatal foals after resuscitation, such as acute renal failure.
  • The document also highlights the possible therapeutic application of renal replacement therapy using hemodiafiltration in neonatal foals suffering from acute kidney damage.
  • The case serves as a guide for future research and clinical decisions, helping to improve treatment strategies for post-resuscitation complications in newborn animals.

Cite This Article

APA
Wong DM, Ruby RE, Eatroff A, Yaeger MJ. (2017). Use of Renal Replacement Therapy in a Neonatal Foal with Postresuscitation Acute Renal Failure. J Vet Intern Med, 31(2), 593-597. https://doi.org/10.1111/jvim.14665

Publication

Journal of veterinary internal medicine
ISSN: 1939-1676
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 31
Issue: 2
Pages: 593-597

Researcher Affiliations

Wong, D M
  • Section of Equine Medicine, Department of Veterinary Clinical Sciences, Lloyd Veterinary Medical Center, Iowa State University, Ames, IA.
Ruby, R E
  • Section of Equine Medicine, Department of Veterinary Clinical Sciences, Lloyd Veterinary Medical Center, Iowa State University, Ames, IA.
Eatroff, A
  • ACCESS Specialty Animal Hospitals, Department of Internal Medicine, Nephrology and Dialysis, Culver City, CA.
Yaeger, M J
  • Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA.

MeSH Terms

  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / therapy
  • Acute Kidney Injury / veterinary
  • Animals
  • Animals, Newborn
  • Cardiopulmonary Resuscitation / adverse effects
  • Cardiopulmonary Resuscitation / veterinary
  • Female
  • Hemodiafiltration / veterinary
  • Horse Diseases / etiology
  • Horse Diseases / therapy
  • Horses
  • Renal Replacement Therapy / veterinary

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Citations

This article has been cited 1 times.
  1. Fouché N, Graubner C, Lanz S, Schweighauser A, Francey T, Gerber V. Acute kidney injury due to Leptospira interrogans in 4 foals and use of renal replacement therapy with intermittent hemodiafiltration in 1 foal.. J Vet Intern Med 2020 Mar;34(2):1007-1012.
    doi: 10.1111/jvim.15713pubmed: 31999382google scholar: lookup
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