Validation of the bispectral index as an indicator of anesthetic depth in Thoroughbred horses anesthetized with sevoflurane.
Abstract: To evaluate the bispectral index (BIS) as an indicator of anesthetic depth in Thoroughbred horses, BIS values were measured at multiple stages of sevoflurane anesthesia in five horses anesthetized with guaifenesin and thiopental following premedication with xylazine. There was no significant difference between the BIS values recorded at end-tidal sevoflurane concentrations of 2.8% (median 60 ranging from 47 to 68) and 3.5% (median 71 ranging from 49 to 82) in anesthetized horses. These BIS values during anesthesia were significantly lower (P<0.01) than those in awake horses (median 98 ranging from 98 to 98) or sedated horses (median 92 ranging from 80 to 93). During the recovery phase, the BIS values gradually increased over time but did not significantly increase until the horses showed movement. In conclusion, the BIS value could be useful as an indicator of awakening during the recovery period in horses, as previous reported.
Publication Date: 2016-12-15 PubMed ID: 27974877PubMed Central: PMC5155136DOI: 10.1294/jes.27.169Google Scholar: Lookup
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Summary
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The research discusses validation of bispectral index (BIS) as a significant indicator of the depth of anesthesia in Thoroughbred horses. The BIS values are measured under multiple stages of sevoflurane anesthesia and the study suggests that these values could be beneficial for monitoring recovery period in horses.
Objective of the Research
- The main objective of the research is to evaluate the Bispectral index (BIS) as an indicator for monitoring the depth of anesthesia in Thoroughbred horses anesthetized with Sevoflurane.
Methodology
- Five Thoroughbred horses were used for the experiment. The horses were premedicated with xylazine and then anesthetized with guaifenesin and thiopental.
- BIS values were recorded at different stages of sevoflurane anesthesia and these values were compared with the BIS values when the horses were awake, sedated and during the recovery phase.
Findings
- The BIS values at end-tidal sevoflurane concentrations of 2.8% and 3.5% showed no significant difference in anesthetized horses. Hence, these levels of anesthesia could be considered safe and appropriate for surgical procedures in horses.
- Compare to the above BIS values, BIS values under awake conditions or sedated conditions were significantly higher indicating the effect of anesthesia in dropping the BIS values.
- BIS values showed a gradual increase during the recovery phase and a more significant increase was noticeable when the horses showed movement. This indicates that BIS values could be effectively used for monitoring the recovery phase.
Conclusion
- The study concludes that BIS is a useful indicator of the level of anesthesia and the recovery phase in Thoroughbred horses anesthetized with sevoflurane.
Cite This Article
APA
Tokushige H, Kakizaki M, Ode H, Okano A, Okada J, Kuroda T, Wakuno A, Ohta M.
(2016).
Validation of the bispectral index as an indicator of anesthetic depth in Thoroughbred horses anesthetized with sevoflurane.
J Equine Sci, 27(4), 169-173.
https://doi.org/10.1294/jes.27.169 Publication
Researcher Affiliations
- Racehorse Clinic, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan.
- Racehorse Clinic, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan.
- Racehorse Clinic, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan.
- Racehorse Clinic, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan.
- Racehorse Clinic, Ritto Training Center, Japan Racing Association, Shiga 520-3085, Japan.
- Equine Research Institute, Japan Racing Association, Tochigi 329-0412, Japan.
- Racehorse Clinic, Ritto Training Center, Japan Racing Association, Shiga 520-3085, Japan.
- Equine Research Institute, Japan Racing Association, Tochigi 329-0412, Japan.
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This article includes 19 references
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Citations
This article has been cited 2 times.- Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature.. Animals (Basel) 2021 Jun 14;11(6).
- Santangelo B, Robin A, Simpson K, Potier J, Guichardant M, Portier K. The Modification and Performance of a Large Animal Anesthesia Machine (Tafonius(®)) in Order to Deliver Xenon to a Horse.. Front Vet Sci 2017;4:162.
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