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Canadian journal of veterinary research = Revue canadienne de recherche veterinaire1996; 60(2); 158-160;

Viability of split-thickness skin grafts attached with fibrin glue.

Abstract: Full-thickness, circular, cutaneous wounds (4 cm diameter) were created on metacarpi and metatarsi of 5 horses. On day 6, all 4 wounds on each horse received a stored autogenous split-thickness sheet graft. Grafts were obtained from the horse's ventrolateral thorax with a pneumatic dermatome at the time the cutaneous wounds were created. Grafts were coapted to the granulation bed of 2 wounds of each horse with fibrin glue. Grafts were coapted to the cutaneous margin of all 4 wounds of each horse with cyanoacrylate glue. Bandages were changed daily until the study ended at 14 d. When the bandages were changed, ointment containing neomycin, polymyxin B, and bacitracin was applied to all wounds. The viable area of graft was measured on post-grafting d 14 and calculated with a micro-processor. Split-thickness sheet-grafts attached to granulation beds on the metacarpi and metatarsi with fibrin glue had no greater survival than did grafts attached without fibrin glue (P > 0.05).
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Publication Date: 1996-04-01 PubMed ID: 8785723PubMed Central: PMC1263823
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research paper aims to determine the effectiveness of fibrin glue in attaching split-thickness skin grafts on full-thickness cutaneous wounds in horses. The study discovered that using fibrin glue to attach grafts doesn’t significantly improve the graft survival compared to grafts attached without fibrin glue.

Research Methodology and Experiment

  • The study was conducted on five horses, with all four wounds on each horse receiving a split-thickness sheet graft.
  • Full thickness, circular, cutaneous wounds with a diameter of 4 cm were intentionally created on the horses’ metacarpi and metatarsi.
  • The grafts were obtained from the horses’ ventrolateral thorax using a pneumatic dermatome at the time of wound creation.
  • On day six, these grafts were coapted to the granulation bed of two wounds with fibrin glue, and to cutaneous margins of all four wounds with cyanoacrylate glue.
  • The bandages on the wounds were changed daily, and each time an ointment containing neomycin, polymyxin B, and bacitracin was applied.
  • The study concluded on the 14th day post-grafting.

Data Collection and Analysis

  • On the 14th day, the viable area of the graft was measured and computed using a microprocessor.
  • The survival rate of the grafts attached with fibrin glue to the granulation beds on the metacarpi and metatarsi was compared to the survival rate of those attached without the glue.

Research Findings

  • The study found that using fibrin glue to attach split-thickness skin grafts did not significantly improve the graft survival rate compared to those attached without the glue.
  • The survival rates of grafts attached to granulation beds on the metacarpi and metatarsi with fibrin glue were statistically insignificant from those attached without fibrin glue (P > 0.05).

In conclusion, the viability of split-thickness skin grafts doesn’t improve significantly by attaching them with fibrin glue, indicating little benefit in using fibrin glue for this purpose.

Cite This Article

APA
Schumacher J, Ford TS, Brumbaugh GW, Honnas CM. (1996). Viability of split-thickness skin grafts attached with fibrin glue. Can J Vet Res, 60(2), 158-160.

Publication

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
ISSN: 0830-9000
NlmUniqueID: 8607793
Country: Canada
Language: English
Volume: 60
Issue: 2
Pages: 158-160

Researcher Affiliations

Schumacher, J
  • Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843-4475, USA.
Ford, T S
    Brumbaugh, G W
      Honnas, C M

        MeSH Terms

        • Animals
        • Cyanoacrylates
        • Female
        • Fibrin
        • Horses
        • Male
        • Metacarpus
        • Metatarsus
        • Orchiectomy
        • Skin Transplantation / methods
        • Skin Transplantation / veterinary
        • Wounds and Injuries

        References

        This article includes 6 references
        1. Ann Surg. 1925 Dec;82(6):871-9
          pubmed: 17865372
        2. Am J Vet Res. 1992 Sep;53(9):1572-4
          pubmed: 1416357
        3. Vet Surg. 1987 Sep-Oct;16(5):358-61
          pubmed: 3333709
        4. Laryngol Rhinol Otol (Stuttg). 1985 Feb;64(2):89-92
          pubmed: 3872393
        5. Vet Clin North Am Equine Pract. 1989 Dec;5(3):591-614
          pubmed: 2691033
        6. Plast Reconstr Surg. 1979 Mar;63(3):323-32
          pubmed: 368835

        Citations

        This article has been cited 1 times.
        1. . Association of Primate Veterinarians Guidelines for Wound Management of Nonhuman Primates. J Am Assoc Lab Anim Sci 2022 Jul 1;61(4):315-319.
          pubmed: 35918830
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