Virucidal effect of commercially available disinfectants on equine group A rotavirus.
Abstract: Although many disinfectants are commercially available in the veterinary field, information on the virucidal effects of disinfectants against equine group A rotavirus (RVA) is limited. We evaluated the performance of commercially available disinfectants against equine RVA. Chlorine- and iodine-based disinfectants showed virucidal effects, but these were reduced by the presence of organic matter. Glutaraldehyde had a virucidal effect regardless of the presence of organic matter, but the effect was reduced by low temperature or short reaction time, or both. Benzalkonium chloride had the greatest virucidal effect among the three quaternary ammonium compounds examined, but its effect was reduced by the presence of organic matter or by low temperature or a short reaction time. These findings will be useful for preventing the spread of equine RVA infection.
Publication Date: 2014-03-28 PubMed ID: 24681569PubMed Central: PMC4143650DOI: 10.1292/jvms.14-0018Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research investigates the effectiveness of different commercially available disinfectants on the equine group A rotavirus. The study found that chlorine- and iodine-based disinfectants have virucidal effects, but these are diminished by the presence of organic matter. Glutaraldehyde showed promise but was less effective at lower temperatures or with short reaction times. Of three different quaternary ammonium compounds examined, benzalkonium chloride demonstrated the most significant virucidal effect.
Introduction
- The study focused on the effectiveness of various commercially available disinfectants against equine group A rotavirus (RVA).
Virucidal Effects of Disinfectants
- Different disinfectants were tested, and the results suggest that chlorine- and iodine-based disinfectants have virucidal effects.
- However, their effectiveness is considerably reduced in the presence of organic matter.
- Glutaraldehyde, another disinfectant, also showed a virucidal effect, but it was less effective at lower temperatures or when applied for a short period.
Effectiveness of Quaternary Ammonium Compounds
- Among the three quaternary ammonium compounds evaluated in this study, benzalkonium chloride had the greatest virucidal effect.
- However, similarly to the previously described disinfectants, benzalkonium chloride’s virucidal capability was also reduced in the presence of organic matter or by less favourable conditions like low temperatures or short reaction time.
Conclusion
- The findings of the research provide insightful information that could help in the formulation and selection of disinfectants and in developing protocols for preventing the spread of equine RVA infection.
Cite This Article
APA
Nemoto M, Bannai H, Tsujimura K, Yamanaka T, Kondo T.
(2014).
Virucidal effect of commercially available disinfectants on equine group A rotavirus.
J Vet Med Sci, 76(7), 1061-1063.
https://doi.org/10.1292/jvms.14-0018 Publication
Researcher Affiliations
- Epizootic Research Center, Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi 329-0412, Japan.
MeSH Terms
- Animals
- Disinfectants / pharmacology
- Horse Diseases / prevention & control
- Horse Diseases / virology
- Horses
- Rotavirus / classification
- Rotavirus / drug effects
- Rotavirus Infections / prevention & control
- Rotavirus Infections / veterinary
References
This article includes 18 references
- Browning GF. Equine rotavirus infections. pp. 127–135. In: Virus Infections of Equines (Studdert, M.J. ed.), Elsevier Science B. V., Amsterdam.
- Conner ME, Darlington RW. Rotavirus infection in foals.. Am J Vet Res 1980 Oct;41(10):1699-703.
- Dwyer RM. Equine Rotavirus. pp. 181–183. In: Equine Infectious Diseases (Sellon, D.C. and Long, M.T. eds.), Saunders Elsevier, St. Louis.
- Estes MK, Greenberg HB. Rotaviruses. pp. 1347–1401. In: Fields Virology, 6th ed. (Knipe, D.M. and Howley, P.M. eds.), Lippincott Williams & Wilkins, Philadelphia.
- Ferrari M, Gualandi GL, Minelli MF. A study on the sensitivity of bovine rotavirus to some chemical agents.. Microbiologica 1986 Apr;9(2):147-50.
- Goto H, Tsunemitsu H, Horimoto M, Shimizu K, Urasawa T, Urasawa S, Ohishi H, Ikemoto Y. A sero-epidemiological study on rotavirus infection in horses. Bull. Equine Res. Inst. 18: 129–135.
- Graham DY, Dufour GR, Estes MK. Minimal infective dose of rotavirus.. Arch Virol 1987;92(3-4):261-71.
- Imagawa H, Tanaka T, Sekiguchi K, Fukunaga Y, Anzai T, Minamoto N, Kamada M. Electropherotypes, serotypes, and subgroups of equine rotaviruses isolated in Japan.. Arch Virol 1993;131(1-2):169-76.
- Imagawa H, Wada R, Hirasawa K, Akiyama Y, Oda T. Isolation of equine rotavirus in cell cultures from foals with diarrhea.. Nihon Juigaku Zasshi 1984 Feb;46(1):1-9.
- Kawana R, Kitamura T, Nakagomi O, Matsumoto I, Arita M, Yoshihara N, Yanagi K, Yamada A, Morita O, Yoshida Y, Furuya Y, Chiba S. Inactivation of human viruses by povidone-iodine in comparison with other antiseptics.. Dermatology 1997;195 Suppl 2:29-35.
- Nemoto M, Tsunemitsu H, Murase H, Nambo Y, Sato S, Orita Y, Imagawa H, Bannai H, Tsujimura K, Yamanaka T, Matsumura T, Kondo T. Antibody response in vaccinated pregnant mares to recent G3BP[12] and G14P[12] equine rotaviruses.. Acta Vet Scand 2012 Nov 6;54(1):63.
- Payment P, Morin E. Minimal infective dose of the OSU strain of porcine rotavirus.. Arch Virol 1990;112(3-4):277-82.
- Sattar SA, Raphael RA, Lochnan H, Springthorpe VS. Rotavirus inactivation by chemical disinfectants and antiseptics used in hospitals.. Can J Microbiol 1983 Oct;29(10):1464-9.
- Smith DR, Wang RS. Glutaraldehyde exposure and its occupational impact in the health care environment.. Environ Health Prev Med 2006 Jan;11(1):3-10.
- Springthorpe VS, Grenier JL, Lloyd-Evans N, Sattar SA. Chemical disinfection of human rotaviruses: efficacy of commercially-available products in suspension tests.. J Hyg (Lond) 1986 Aug;97(1):139-61.
- Tan JA, Schnagl RD. Inactivation of a rotavirus by disinfectants.. Med J Aust 1981 Jan 10;1(1):19-23.
- Tan JA, Schnagl RD. Rotavirus inactivated by a hypochlorite-based disinfectant: a reappraisal.. Med J Aust 1983 Jun 11;1(12):550.
- Woode GN. Epizootiology of bovine rotavirus infection.. Vet Rec 1978 Jul 15;103(3):44-6.
Citations
This article has been cited 5 times.- Miyaoka Y, Kadota C, Kabir MH, Hakim H, Yamaguchi M, Hasan MA, Shoham D, Murakami H, Kobayashi S, Takehara K. Isolation, molecular characterization, and disinfectants susceptibility of swine-carried mammalian orthoreoviruses in Japan in 2020-2022.. J Vet Med Sci 2023 Feb 1;85(2):185-193.
- Nemoto M, Matsumura T. Equine rotavirus infection.. J Equine Sci 2021 Mar;32(1):1-9.
- Dagher D, Ungar K, Robison R, Dagher F. The wide spectrum high biocidal potency of Bioxy formulation when dissolved in water at different concentrations.. PLoS One 2017;12(2):e0172224.
- Nemoto M, Oue Y, Higuchi T, Kinoshita Y, Bannai H, Tsujimura K, Yamanaka T, Kondo T. Low prevalence of equine coronavirus in foals in the largest thoroughbred horse breeding region of Japan, 2012-2014.. Acta Vet Scand 2015 Sep 22;57(1):53.
- Tsujimura K, Murase H, Bannai H, Nemoto M, Yamanaka T, Kondo T. Efficacy of five commercial disinfectants and one anionic surfactant against equine herpesvirus type 1.. J Vet Med Sci 2015 Nov;77(11):1545-8.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
