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The Journal of veterinary medical science2014; 76(7); 1061-1063; doi: 10.1292/jvms.14-0018

Virucidal effect of commercially available disinfectants on equine group A rotavirus.

Abstract: Although many disinfectants are commercially available in the veterinary field, information on the virucidal effects of disinfectants against equine group A rotavirus (RVA) is limited. We evaluated the performance of commercially available disinfectants against equine RVA. Chlorine- and iodine-based disinfectants showed virucidal effects, but these were reduced by the presence of organic matter. Glutaraldehyde had a virucidal effect regardless of the presence of organic matter, but the effect was reduced by low temperature or short reaction time, or both. Benzalkonium chloride had the greatest virucidal effect among the three quaternary ammonium compounds examined, but its effect was reduced by the presence of organic matter or by low temperature or a short reaction time. These findings will be useful for preventing the spread of equine RVA infection.
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Publication Date: 2014-03-28 PubMed ID: 24681569PubMed Central: PMC4143650DOI: 10.1292/jvms.14-0018Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the effectiveness of different commercially available disinfectants on the equine group A rotavirus. The study found that chlorine- and iodine-based disinfectants have virucidal effects, but these are diminished by the presence of organic matter. Glutaraldehyde showed promise but was less effective at lower temperatures or with short reaction times. Of three different quaternary ammonium compounds examined, benzalkonium chloride demonstrated the most significant virucidal effect.

Introduction

  • The study focused on the effectiveness of various commercially available disinfectants against equine group A rotavirus (RVA).

Virucidal Effects of Disinfectants

  • Different disinfectants were tested, and the results suggest that chlorine- and iodine-based disinfectants have virucidal effects.
  • However, their effectiveness is considerably reduced in the presence of organic matter.
  • Glutaraldehyde, another disinfectant, also showed a virucidal effect, but it was less effective at lower temperatures or when applied for a short period.

Effectiveness of Quaternary Ammonium Compounds

  • Among the three quaternary ammonium compounds evaluated in this study, benzalkonium chloride had the greatest virucidal effect.
  • However, similarly to the previously described disinfectants, benzalkonium chloride’s virucidal capability was also reduced in the presence of organic matter or by less favourable conditions like low temperatures or short reaction time.

Conclusion

  • The findings of the research provide insightful information that could help in the formulation and selection of disinfectants and in developing protocols for preventing the spread of equine RVA infection.

Cite This Article

APA
Nemoto M, Bannai H, Tsujimura K, Yamanaka T, Kondo T. (2014). Virucidal effect of commercially available disinfectants on equine group A rotavirus. J Vet Med Sci, 76(7), 1061-1063. https://doi.org/10.1292/jvms.14-0018

Publication

The Journal of veterinary medical science
ISSN: 1347-7439
NlmUniqueID: 9105360
Country: Japan
Language: English
Volume: 76
Issue: 7
Pages: 1061-1063

Researcher Affiliations

Nemoto, Manabu
  • Epizootic Research Center, Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi 329-0412, Japan.
Bannai, Hiroshi
    Tsujimura, Koji
      Yamanaka, Takashi
        Kondo, Takashi

          MeSH Terms

          • Animals
          • Disinfectants / pharmacology
          • Horse Diseases / prevention & control
          • Horse Diseases / virology
          • Horses
          • Rotavirus / classification
          • Rotavirus / drug effects
          • Rotavirus Infections / prevention & control
          • Rotavirus Infections / veterinary

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          Citations

          This article has been cited 6 times.
          1. Miyaoka Y, Kadota C, Kabir MH, Hakim H, Yamaguchi M, Hasan MA, Shoham D, Murakami H, Kobayashi S, Takehara K. Isolation, molecular characterization, and disinfectants susceptibility of swine-carried mammalian orthoreoviruses in Japan in 2020-2022. J Vet Med Sci 2023 Feb 1;85(2):185-193.
            doi: 10.1292/jvms.22-0476pubmed: 36574999google scholar: lookup
          2. Nemoto M, Matsumura T. Equine rotavirus infection. J Equine Sci 2021 Mar;32(1):1-9.
            doi: 10.1294/jes.32.1pubmed: 33776534google scholar: lookup
          3. Dagher D, Ungar K, Robison R, Dagher F. The wide spectrum high biocidal potency of Bioxy formulation when dissolved in water at different concentrations. PLoS One 2017;12(2):e0172224.
            doi: 10.1371/journal.pone.0172224pubmed: 28207828google scholar: lookup
          4. Nemoto M, Oue Y, Higuchi T, Kinoshita Y, Bannai H, Tsujimura K, Yamanaka T, Kondo T. Low prevalence of equine coronavirus in foals in the largest thoroughbred horse breeding region of Japan, 2012-2014. Acta Vet Scand 2015 Sep 22;57(1):53.
            doi: 10.1186/s13028-015-0149-4pubmed: 26395082google scholar: lookup
          5. Tsujimura K, Murase H, Bannai H, Nemoto M, Yamanaka T, Kondo T. Efficacy of five commercial disinfectants and one anionic surfactant against equine herpesvirus type 1. J Vet Med Sci 2015 Nov;77(11):1545-8.
            doi: 10.1292/jvms.15-0030pubmed: 26074409google scholar: lookup
          6. Sobhy NM, Quinonez-Munoz A, Aboubakr HA, Youssef CRB, Ojeda-Barría G, Mendoza-Fernández J, Goyal SM. In vitro virucidal activity of a commercial disinfectant against viruses of domestic animals and poultry. Front Vet Sci 2023;10:1276031.
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