Volume of the synovia in certain joint cavities in the horse.
Abstract: A method of determining the volumes of synovia in certain articular cavities in the horse is described. The method is based on the degree of dilution of human serum albumin labelled with I that is injected into the joint. It is shown that uniform distribution of the injected substance is attained within 20 min post injection. The elimination of the labelled substance was found to follow the pattern of a single exponential function. The following volumes of synovia were determined (mean ± s) : hock, 39.8 ± 2.1 ml; radio-carpal, 12.6 ±1.5 ml; intercarpal, 14.9 ± 0.6 ml; foreleg fetlock joint, 12.5 ± 1.0 ml. En metod för att bestämma synoviavolymen i vissa ledkaviteter hos häst beskrives. Metoden baseras på utspädningen av humant serumalbumin markt med I som injiceras i leden. Det visas att den märkta substansen är jämnt fördelad i leden 20 min efter injektionen. Eliminationen av det märkta albuminet kan beskrivas matematiskt som en enkel exponentiell funktion. Följande synoviavolymer uppmättes: has, 39,8 ± 2,1 ml (Medeltal ± s) ; radio-carpal, 12,6 ± 1,5 ml; intercarpal, 14,9 ± 0,6 ml, kotled, framben, 12,5 ± 1,0 ml.
Publication Date: 1981-01-01 PubMed ID: 7258028PubMed Central: PMC8300501DOI: 10.1186/BF03547202Google Scholar: Lookup
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- Journal Article
Summary
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This study devises an approach to measure the synovia volume, a type of joint fluid, in specific parts of a horse’s body. The method utilizes the dilution level of a labelled human serum albumin injected into the joint, and its distribution pattern and elimination rates were scrutinized.
Measurement Method
- The researchers developed a method to gauge the volumes of synovia present in a horse’s joint cavities.
- The technique involves the use of human serum albumin marked with iodine (I). The tagged serum albumin is injected into the joint, functioning as a marker that can better visualize the distribution of the fluid and aid in volume measurements.
Distribution and Elimination
- The study points out that uniform distribution of the injected substance is achieved within twenty minutes after injection. This distribution homogeneity implies that the injected albumin rapidly diffuses in synovial fluid, enabling accurate volume assessment.
- The removal of the labeled substance, or albumin, is mapped following a single exponential function, suggesting a consistent rate of elimination. Understanding this informs how quickly the joint absorbs and processes the synovial fluid that’s been marked.
Synovia Volumes
- The study provides the mean volumes (± standard deviation) of synovia in various horse joint regions, including the hock (39.8 ± 2.1 ml), the radio-carpal (12.6 ±1.5 ml), the intercarpal (14.9 ± 0.6 ml), and the fetlock joint of the foreleg (12.5 ± 1.0 ml).
- These findings provide insights into the liquid volumes within these specified areas of a horse’s body, potentially informing veterinarians and researchers about normal fluid levels in these joints.
Cite This Article
APA
Ekman L, Nilsson G, Persson L, Lumsden JH.
(1981).
Volume of the synovia in certain joint cavities in the horse.
Acta Vet Scand, 22(1), 23-31.
https://doi.org/10.1186/BF03547202 Publication
Researcher Affiliations
MeSH Terms
- Animals
- Horses / anatomy & histology
- Joints / anatomy & histology
- Synovial Fluid
References
This article includes 6 references
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Citations
This article has been cited 12 times.- Sladek S, Kearney C, Crean D, Brama PAJ, Tajber L, Fawcett K, Labberte MC, Leggett B, Brayden DJ. Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation. Drug Deliv Transl Res 2018 Oct;8(5):1421-1435.
- Castro Martins M, Peffers MJ, Lee K, Rubio-Martinez LM. Effects of stanozolol on normal and IL-1β-stimulated equine chondrocytes in vitro. BMC Vet Res 2018 Mar 20;14(1):103.
- Rubio-Martínez LM, Rioja E, Castro Martins M, Wipawee S, Clegg P, Peffers MJ. Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. BMC Vet Res 2017 Nov 7;13(1):318.
- Joswig AJ, Mitchell A, Cummings KJ, Levine GJ, Gregory CA, Smith R 3rd, Watts AE. Repeated intra-articular injection of allogeneic mesenchymal stem cells causes an adverse response compared to autologous cells in the equine model. Stem Cell Res Ther 2017 Feb 28;8(1):42.
- Carmona JU, Ríos DL, López C, Álvarez ME, Pérez JE, Bohórquez ME. In vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide. BMC Vet Res 2016 Jul 1;12(1):135.
- Duesterdieck-Zellmer KF, Moneta L, Ott JF, Larson MK, Gorman EM, Hunter B, Löhr CV, Payton ME, Morré JT, Maier CS. Effects of low and high dose intraarticular tiludronate on synovial fluid and clinical variables in healthy horses-a preliminary investigation. PeerJ 2014;2:e534.
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- Li W, Abram F, Pelletier JP, Raynauld JP, Dorais M, d'Anjou MA, Martel-Pelletier J. Fully automated system for the quantification of human osteoarthritic knee joint effusion volume using magnetic resonance imaging. Arthritis Res Ther 2010;12(5):R173.
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