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Acta veterinaria Scandinavica1981; 22(1); 23-31; doi: 10.1186/BF03547202

Volume of the synovia in certain joint cavities in the horse.

Abstract: A method of determining the volumes of synovia in certain articular cavities in the horse is described. The method is based on the degree of dilution of human serum albumin labelled with I that is injected into the joint. It is shown that uniform distribution of the injected substance is attained within 20 min post injection. The elimination of the labelled substance was found to follow the pattern of a single exponential function. The following volumes of synovia were determined (mean ± s) : hock, 39.8 ± 2.1 ml; radio-carpal, 12.6 ±1.5 ml; intercarpal, 14.9 ± 0.6 ml; foreleg fetlock joint, 12.5 ± 1.0 ml. En metod för att bestämma synoviavolymen i vissa ledkaviteter hos häst beskrives. Metoden baseras på utspädningen av humant serumalbumin markt med I som injiceras i leden. Det visas att den märkta substansen är jämnt fördelad i leden 20 min efter injektionen. Eliminationen av det märkta albuminet kan beskrivas matematiskt som en enkel exponentiell funktion. Följande synoviavolymer uppmättes: has, 39,8 ± 2,1 ml (Medeltal ± s) ; radio-carpal, 12,6 ± 1,5 ml; intercarpal, 14,9 ± 0,6 ml, kotled, framben, 12,5 ± 1,0 ml.
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Publication Date: 1981-01-01 PubMed ID: 7258028PubMed Central: PMC8300501DOI: 10.1186/BF03547202Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study devises an approach to measure the synovia volume, a type of joint fluid, in specific parts of a horse’s body. The method utilizes the dilution level of a labelled human serum albumin injected into the joint, and its distribution pattern and elimination rates were scrutinized.

Measurement Method

  • The researchers developed a method to gauge the volumes of synovia present in a horse’s joint cavities.
  • The technique involves the use of human serum albumin marked with iodine (I). The tagged serum albumin is injected into the joint, functioning as a marker that can better visualize the distribution of the fluid and aid in volume measurements.

Distribution and Elimination

  • The study points out that uniform distribution of the injected substance is achieved within twenty minutes after injection. This distribution homogeneity implies that the injected albumin rapidly diffuses in synovial fluid, enabling accurate volume assessment.
  • The removal of the labeled substance, or albumin, is mapped following a single exponential function, suggesting a consistent rate of elimination. Understanding this informs how quickly the joint absorbs and processes the synovial fluid that’s been marked.

Synovia Volumes

  • The study provides the mean volumes (± standard deviation) of synovia in various horse joint regions, including the hock (39.8 ± 2.1 ml), the radio-carpal (12.6 ±1.5 ml), the intercarpal (14.9 ± 0.6 ml), and the fetlock joint of the foreleg (12.5 ± 1.0 ml).
  • These findings provide insights into the liquid volumes within these specified areas of a horse’s body, potentially informing veterinarians and researchers about normal fluid levels in these joints.

Cite This Article

APA
Ekman L, Nilsson G, Persson L, Lumsden JH. (1981). Volume of the synovia in certain joint cavities in the horse. Acta Vet Scand, 22(1), 23-31. https://doi.org/10.1186/BF03547202

Publication

Acta veterinaria Scandinavica
ISSN: 0044-605X
NlmUniqueID: 0370400
Country: England
Language: English
Volume: 22
Issue: 1
Pages: 23-31

Researcher Affiliations

Ekman, L
    Nilsson, G
      Persson, L
        Lumsden, J H

          MeSH Terms

          • Animals
          • Horses / anatomy & histology
          • Joints / anatomy & histology
          • Synovial Fluid

          References

          This article includes 6 references
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          Citations

          This article has been cited 12 times.
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          12. Yu R, Jusko WJ. Meta-Analysis and Mechanism-Based Modeling of Synovial and Plasma Pharmacokinetics and Adrenal Suppression Following Intra-Articular Injection of Methylprednisolone Acetate in Horses. J Vet Pharmacol Ther 2025 Jul;48(4):260-273.
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