West Nile virus in Morocco, 2003.
Abstract: West Nile virus (WNV) reemerged in Morocco in September 2003, causing an equine outbreak. A WNV strain isolated from a brain biopsy was completely sequenced. On the basis of phylogenetic analyses, Moroccan WNV strains isolated during the 1996 and 2003 outbreaks were closely related to other strains responsible for equine outbreaks in the western Mediterranean basin.
Publication Date: 2005-03-09 PubMed ID: 15752452PubMed Central: PMC3320441DOI: 10.3201/eid1102.040817Google Scholar: Lookup
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- Journal Article
Summary
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The research article focuses on the reemergence of the West Nile virus (WNV) in Morocco in 2003, which led to an outbreak amongst equines. The virus strain was isolated and its genetic sequence was completely summed up, revealing a close relation to strains that caused similar outbreaks in the Western Mediterranean region in 1996 and 2003.
The West Nile Virus Outbreak
- The study was carried out following a West Nile virus (WNV) outbreak in Morocco in 2003. This outbreak predominantly affected equine populations.
- Medical experts managed to isolate a strain of the virus from a brain biopsy for further study.
The Genetic Sequencing of the Virus
- The isolated virus strain was completely sequenced. Complete sequencing of a viral genome allows researchers to understand the structure and functionality of the virus, aiding in future diagnostic, prevention, and treatment methods.
- The sequencing also helps in identifying the exact type and variant of the virus, critical in the epidemiological study of disease spread and control.
Phylogenetic and Comparative Analysis
- After sequencing, the researchers conducted phylogenetic analyses. This is a specialized study that works out the evolutionary relationships between different species or, in this case, virus strains.
- Through this analysis, it was found that the WNV strains isolated during the 2003 Morocco outbreak were closely related to other strains – specifically, those responsible for equine outbreaks in the western Mediterranean basin during 1996 and 2003.
- Understanding these relationships can provide valuable insight into the origins, spread and future control of the virus.
Cite This Article
APA
Schuffenecker I, Peyrefitte CN, el Harrak M, Murri S, Leblond A, Zeller HG.
(2005).
West Nile virus in Morocco, 2003.
Emerg Infect Dis, 11(2), 306-309.
https://doi.org/10.3201/eid1102.040817 Publication
Researcher Affiliations
- Centre de Référence des Arbovirus, Institut Pasteur, 21 Ave Tony Garnier, 69365 Lyon cedex 07, France. schuffenecker@cervi-lyon.inserm.fr
MeSH Terms
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain / virology
- Cytopathogenic Effect, Viral
- DNA, Viral / chemistry
- DNA, Viral / genetics
- Disease Outbreaks / veterinary
- Female
- Horse Diseases / epidemiology
- Horse Diseases / virology
- Horses
- Male
- Molecular Sequence Data
- Morocco / epidemiology
- Phylogeny
- Polymerase Chain Reaction / veterinary
- Sequence Alignment
- West Nile Fever / epidemiology
- West Nile Fever / veterinary
- West Nile Fever / virology
- West Nile virus / genetics
- West Nile virus / growth & development
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