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Journal of veterinary medicine2019; 2019; 6320515; doi: 10.1155/2019/6320515

Wound Photobiomodulation Treatment Outcomes in Animal Models.

Abstract: The possibilities that photobiomodulation has brought on to the medical field are ever expanding and the scope it has reached is infinite. Determining how this relatively new treatment technique can be incorporated into the veterinary medical field is of interest to many medical professionals. In this review, we examine the treatment outcomes of low-level-laser therapy (LLLT) in different animal models to pinpoint any similarities between the studies. A search was conducted to identify LLLT studies using different animal models with an open or closed wound. The studies were compared to identify the laser parameters that resulted in positive treatment outcomes. The overall result of the studies examined indicated that daily laser exposure at a wavelength of a 600 or 800 nm range was the most beneficial across the rodent studies regardless of health status or wound type. More studies on rabbit, canine, and equine models are needed to explain the inconsistent results reviewed and find the correct treatment parameters for these species. Further research involving LLLT studies that focus on different factors including health status, treatment interval, wavelength, and energy density is needed to help validate our knowledge about the efficacy of using photobiomodulation in the veterinary medical field.
Publication Date: 2019-07-28 PubMed ID: 31467931PubMed Central: PMC6699315DOI: 10.1155/2019/6320515Google Scholar: Lookup
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  • Journal Article
  • Review

Summary

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This research paper provides an extensive review on the effective parameters in low-level-laser therapy (LLLT) in encouraging wound healing and suggests further research towards making these treatments more effective in various animal models including rabbits, canines, and equines.

Overview of the Study and Search

  • The study is primarily a review of numerous other studies focusing on the utilization of low-level-laser therapy (LLLT) as a treatment method in various animal models.
  • The emphasis was on the use of photobiomodulation, a treatment method that stimulates the body’s own cells to promote healing and reduce inflammation, for wound healing.
  • The authors conducted a systematic search to gather and examine studies that used different animal models, with wounds either open or closed, and treated them using LLLT.

Comparison and Result Analysis

  • The individual studies collected were compared on the basis of laser parameters used and the resulting treatment outcomes.
  • The main aim was to identify any recurring similarities in positive treatment outcomes in order to establish a standard, optimal laser parameter for maximum efficiency.
  • The overall result demonstrated that a daily exposure to laser light at a wavelength of either 600 nm or 800 nm was the most beneficial across various rodent studies, regardless of health status or the type of wound.

Need for Additional Studies and Advancement in the Field

  • The researchers identified a need for further studies focusing on rabbit, canine, and equine models. The existing studies on these animal models were found to show inconsistent results, instigating the need for further research to determine the optimal treatment parameters for these species.
  • The authors call for more comprehensive studies involving LLLT, focusing on a plethora of variables. These include the health status of the specimen, treatment intervals, wavelength, and energy density.
  • These additional and exhaustive studies would assist in validating our understanding of the efficiency and versatility of using photobiomodulation in the veterinary medical field, with a slight hint towards its potential applications in the human medical field in future.

Cite This Article

APA
Lopez A, Brundage C. (2019). Wound Photobiomodulation Treatment Outcomes in Animal Models. J Vet Med, 2019, 6320515. https://doi.org/10.1155/2019/6320515

Publication

ISSN: 2356-7708
NlmUniqueID: 101627989
Country: United States
Language: English
Volume: 2019
Pages: 6320515

Researcher Affiliations

Lopez, Alondra
  • Animal and Veterinary Sciences, Cal Poly Pomona, Pomona 91768, USA.
Brundage, Cord
  • Animal and Veterinary Sciences, Cal Poly Pomona, Pomona 91768, USA.

Conflict of Interest Statement

The authors declare that they have no conflicts of interest.

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