Annals of emergency medicine.
Publisher:
American College of Emergency Physicians]. St. Louis, MO : Mosby
Frequency: Monthly
Country: United States
Language: English
Author(s):
American College of Emergency Physicians., University Association for Emergency Medicine.
Start Year:1980 -
ISSN:
0196-0644 (Print)
1097-6760 (Electronic)
0196-0644 (Linking)
1097-6760 (Electronic)
0196-0644 (Linking)
Impact Factor
6.2
2022
| NLM ID: | 8002646 |
| (DNLM): | A34870000(s) |
| (OCoLC): | 05729547 |
| Coden: | AEMED3 |
| Classification: | W1 AN574M |
Poisoning with equine phenylbutazone in a racetrack worker. Phenylbutazone is a potent nonsteroidal, anti-inflammatory drug often used by veterinarians to treat racetrack animals. Its use in human beings is limited because of significant adverse effects and the availability of newer, safer drugs. We report the case of a 24-year-old man who ingested 17 g of equine phenylbutazone over a 24-hour period to treat the pain of a toothache. He developed grand mal seizures, coma, hypotension, respiratory and renal failure, and hepatic injury. Serum phenylbutazone concentration obtained approximately eight hours after presentation was 900 micrograms/mL. The pati...
A hemodynamic model for anaphylactic shock. The treatment of cardiovascular collapse and anaphylactic shock is largely empiric. A simple animal model was developed to evaluate the hemodynamic alterations in anaphylaxis. Eight adult New Zealand white rabbits of both sexes were studied. All animals weighed 3.8 kg to 5.3 kg. Sensitization was accomplished with a 2-mL subcutaneous dose of horse serum followed in two days with a 2-mL intravenous (IV) dose. At least 14 days elapsed after the IV dose before a 1-mL challenge dose of horse serum was given. On the day of the challenge dose, a femoral arterial catheter, arterial temperature probe,...