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Biomechanics and modeling in mechanobiology.

Periodical
Biomedical Engineering
Biomechanical Phenomena
Models
Biological
Publisher:
Springer,
Frequency: Six no. a year
Country: Germany
Language: English
Start Year:2002 -
ISSN:
1617-7959 (Print)
1617-7940 (Electronic)
1617-7940 (Linking)
Impact Factor
3.5
2022
NLM ID:101135325
(OCoLC):50249931
LCCN:2002242113
Classification:W1 BI853CP
Mathematical modelling of bone adaptation of the metacarpal subchondral bone in racehorses.
Biomechanics and modeling in mechanobiology    January 17, 2018   Volume 17, Issue 3 877-890 doi: 10.1007/s10237-017-0998-z
Hitchens PL, Pivonka P, Malekipour F, Whitton RC.In Thoroughbred racehorses, fractures of the distal limb are commonly catastrophic. Most of these fractures occur due to the accumulation of fatigue damage from repetitive loading, as evidenced by microdamage at the predilection sites for fracture. Adaptation of the bone in response to training loads is important for fatigue resistance. In order to better understand the mechanism of subchondral bone adaptation to its loading environment, we utilised a square root function defining the relationship between bone volume fraction [Formula: see text] and specific surface [Formula: see text] of the ...
A mechanostatistical approach to cortical bone remodelling: an equine model.
Biomechanics and modeling in mechanobiology    April 11, 2015   Volume 15, Issue 1 29-42 doi: 10.1007/s10237-015-0669-x
Wang X, Thomas CD, Clement JG, Das R, Davies H, Fernandez JW.In this study, the development of a mechanostatistical model of three-dimensional cortical bone remodelling informed with in vivo equine data is presented. The equine model was chosen as it is highly translational to the human condition due to similar Haversian systems, availability of in vivo bone strain and biomarker data, and furthermore, equine models are recommended by the US Federal Drugs Administration for comparative joint research. The model was derived from micro-computed tomography imaged specimens taken from the equine third metacarpal bone, and the Frost-based 'mechanostat' was in...