Current issues in molecular biology.

Periodical
Molecular Biology
Publisher:
Caister Academic Press,. Basel, Switzerland : MDPI (2021)
Frequency: Two no. a year, 2004-
Country: Switzerland
Language: English
Start Year:1999 -
ISSN:
1467-3037 (Print)
1467-3045 (Electronic)
1467-3037 (Linking)
Impact Factor
3.1
2022
NLM ID:100931761
(OCoLC):43079783
Coden:CMBIF6
Classification:W1 CU788LCV
Extracellular Vesicles Isolated from Equine Adipose-Derived Stromal Stem Cells (ASCs) Mitigate Tunicamycin-Induced ER Stress in Equine Corneal Stromal Stem Cells (CSSCs).
Current issues in molecular biology    April 9, 2024   Volume 46, Issue 4 3251-3277 doi: 10.3390/cimb46040204
Meissner JM, Chmieliu0144ska A, Ofri R, Cisu0142o-Sankowska A, Marycz K.Corneal ulcers, characterized by severe inflammation of the cornea, can lead to serious, debilitating complications and may be vision-threatening for horses. In this study, we aimed to investigate the role of endoplasmic reticulum (ER) stress in corneal stem progenitor cell (CSSC) dysfunction and explore the potential of equine adipose-derived stromal stem cell (ASC)-derived extracellular vesicles (EVs) to improve corneal wound healing. We showed that CSSCs expressed high levels of CD44, CD45, and CD90 surface markers, indicating their stemness. Supplementation of the ER-stress-inducer tunicam...
PCR-based Methodologies Used to Detect and Differentiate the Burkholderia pseudomallei complex: B. pseudomallei, B. mallei, and B. thailandensis.
Current issues in molecular biology    August 22, 2013   Volume 16 23-54 
Lowe W, March JK, Bunnell AJ, O'Neill KL, Robison RA.Methods for the rapid detection and differentiation of the Burkholderia pseudomallei complex comprising B. pseudomallei, B. mallei, and B. thailandensis, have been the topic of recent research due to the high degree of phenotypic and genotypic similarities of these species. B. pseudomallei and B. mallei are recognized by the CDC as tier 1 select agents. The high mortality rates of glanders and melioidosis, their potential use as bioweapons, and their low infectious dose, necessitate the need for rapid and accurate detection methods. Although B. thailandensis is generally avirulent in mammals, ...