Laboratory investigation; a journal of technical methods and pathology.
Publisher:
Williams & Wilkins. [New York] : Elsevier Inc. (2023)
Frequency: Monthly,
Country: United States
Language: English
Author(s):
International Academy of Pathology., International Association of Medical Museums., United States and Canadian Academy of Pathology.
Start Year:1952 -
ISSN:
0023-6837 (Print)
1530-0307 (Electronic)
0023-6837 (Linking)
1530-0307 (Electronic)
0023-6837 (Linking)
Impact Factor
5
2022
| NLM ID: | 0376617 |
| (DNLM): | L01020000(s) |
| (OCoLC): | 01755414 |
| Coden: | LAINAW |
| LCCN: | 55000219 |
| Classification: | W1 LA208 |
An inherited connective tissue disease in the horse. The hyperextensible, fragile skin of two related horses was compared with the skin of eight normal horses. Skin sections were examined by light microscopy and transmission electron microscopy. The deep dermal layer of the dorsal abdomen was much thinner in the affected horses, and contained bundles of collagen fibers which were more loosely packed. Within individual fibers, the fibrils were frequently curved and nonparallel rather than straight and parallel. Both of the affected animals had a greater range of fibril diameters than a normal horse. They had some unusually thick fibrils with very...