Nature reviews. Cancer.

Periodical

Neoplasms

Research

Publisher:

Nature Pub. Group,

Frequency: Monthly

Country: England

Language: English

Start Year:2001 -

ISSN:

1474-175X (Print)
1474-1768 (Electronic)
1474-175X (Linking)

View Journal Website

NLM Catalog

Impact Factor

78.5

2022

NLM ID:	101124168
(OCoLC):	48623853
LCCN:	2001243419
Classification:	W1 NA839F

Mechanisms of cancer resistance in long-lived mammals.

Nature reviews. Cancer April 7, 2018 Volume 18, Issue 7 433-441 doi: 10.1038/s41568-018-0004-9

Seluanov A, Gladyshev VN, Vijg J, Gorbunova V.Cancer researchers have traditionally used the mouse and the rat as staple model organisms. These animals are very short-lived, reproduce rapidly and are highly prone to cancer. They have been very useful for modelling some human cancer types and testing experimental treatments; however, these cancer-prone species offer little for understanding the mechanisms of cancer resistance. Recent technological advances have expanded bestiary research to non-standard model organisms that possess unique traits of very high value to humans, such as cancer resistance and longevity. In recent years, several...