Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Pigment cell & melanoma research.
Publisher:
Blackwell Munksgaard,
Frequency: Bimonthly
Country: England
Language: English
Author(s):
International Federation of Pigment Cell Societies., Society for Melanoma Research.
Start Year:2008 -
ISSN:
1755-1471 (Print)
1755-148X (Electronic)
1755-1471 (Linking)
1755-148X (Electronic)
1755-1471 (Linking)
Impact Factor
4.3
2022
| NLM ID: | 101318927 |
| (OCoLC): | 212372703 |
| LCCN: | 2008243258 |
| Classification: | W1 PI24K |
Melanin as a Multifunctional Molecular System: Biosynthesis, Genetics, and Functional Roles in Livestock Species. Melanin is the primary pigment found in the skin, hair, wool and feathers of many vertebrates and plays a crucial role in determining the physical appearance and physiological performance of livestock species. Melanin functions in thermoregulation as well as coloration, photoprotection, and adaptation to diverse environmental conditions. This review examines the biosynthesis of melanin and the genetics of melanogenesis in major livestock species such as cattle, sheep, goats, pigs, horses, and poultry, and the roles of melanin-based pigmentation within different systems of animal production. Th...
Identification of a melanocyte-specific, microphthalmia-associated transcription factor-dependent regulatory element in the intronic duplication causing hair greying and melanoma in horses. Greying with age in horses is an autosomal dominant trait, characterized by hair greying, high incidence of melanoma and vitiligo-like depigmentation. Previous studies have revealed that the causative mutation for this phenotype is a 4.6-kb intronic duplication in STX17 (Syntaxin 17). By using reporter constructs in transgenic zebrafish, we show that a construct containing two copies of the duplicated sequence acts as a strong enhancer in neural crest cells and has subsequent melanophore-specific activity during zebrafish embryonic development whereas a single copy of the duplicated sequence a...
