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Vaccines.

Periodical
Vaccines
Publisher:
MDPI AG
Frequency: Quarterly
Country: Switzerland
Language: English
Author(s):
Multidisciplinary Digital Publishing Institute.
Start Year:2012 -
ISSN:
2076-393X (Electronic)
2076-393X (Linking)
Impact Factor
7.8
2022
NLM ID:101629355
(OCoLC):852743569
Coden:VBSABP
LCCN:2014243731
Impact of Mixed Equine Influenza Vaccination on Correlate of Protection in Horses.
Vaccines    October 4, 2018   Volume 6, Issue 4 71 doi: 10.3390/vaccines6040071
Dilai M, Piro M, El Harrak M, Fougerolle S, Dehhaoui M, Dikrallah A, Legrand L, Paillot R, Fassi Fihri O.To evaluate the humoral immune response to mixed Equine Influenza vaccination, a common practice in the field, an experimental study was carried out on 42 unvaccinated thoroughbred weanling foals divided into six groups of seven. Three groups were vaccinated using a non-mixed protocol (Equilis Prequenza-Te, Proteqflu-Te or Calvenza-03) and three other groups were vaccinated using a mix of the three vaccines mentioned previously. Each weanling underwent a primary EI vaccination schedule composed of two primary immunisations (V1 and V2) four weeks apart followed by a third boost immunisation (V3...
The Immunity Gap Challenge: Protection against a Recent Florida Clade 2 Equine Influenza Strain.
Vaccines    July 2, 2018   Volume 6, Issue 3 38 doi: 10.3390/vaccines6030038
Paillot R, Garrett D, Lopez-Alvarez MR, Birand I, Montesso F, Horspool L.Vaccination is one of the most effective tools for limiting the impact of equine influenza (EI). The humoral immunity established following a primary vaccination course can decrease significantly between the second (V2) and third immunisations (V3), leaving some horses insufficiently protected for several weeks. This so-called "immunity gap" poses a challenge to all EI vaccines. During this period, the EI infection of vaccinated animals may be followed by marked clinical signs and virus shedding. However, several EI vaccines have been shown to stimulate equine influenza virus (EIV)-specific ce...
Equine Vaccines: How, When and Why? Report of the Vaccinology Session, French Equine Veterinarians Association, 2016, Reims.
Vaccines    December 4, 2017   Volume 5, Issue 4 46 doi: 10.3390/vaccines5040046
Paillot R, Marcillaud Pitel C, D'Ablon X, Pronost S.To date, vaccination is one of the most efficient methods of prevention against equine infectious diseases. The vaccinology session, which was organised during the annual meeting of the French Equine Veterinarians Association (AVEF) at Reims (France) in 2016, aimed to approach three subjects of importance for the equine industry. Vaccination against three major equine diseases were used as examples: equine influenza (equine influenza virus), rhinopneumonitis (equine herpes virus 1/4), and tetanus ( neuro-toxin). (1) Emergency vaccination: while it has been very successful to reduce the impact ...
Equine PBMC Cytokines Profile after In Vitro α- and γ-EHV Infection: Efficacy of a Parapoxvirus Ovis Based-Immunomodulator Treatment.
Vaccines    September 19, 2017   Volume 5, Issue 3 28 doi: 10.3390/vaccines5030028
Hue ES, Richard EA, Fortier CI, Fortier GD, Paillot R, Raue R, Pronost SL.Equine herpesviruses (EHV) infect horses early during life and the persistence of these viruses through establishment of latency represents a real risk. A better understanding of the immune response to EHV infection is necessary to improve our methods of prevention and decrease the risk of transmission. The objectives of this study were to characterise the cytokine gene expression profile of peripheral blood mononuclear cells (PBMC) after in vitro EHV-1, EHV-4, and EHV-2 infection and to determine the efficacy of inactivated (iPPVO) against these 3 viruses. PBMC were isolated from 3 horses an...
A Systematic Review of Recent Advances in Equine Influenza Vaccination.
Vaccines    November 14, 2014   Volume 2, Issue 4 797-831 doi: 10.3390/vaccines2040797
Paillot R.Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine. Several other strateg...
Identifying the Conditions Under Which Antibodies Protect Against Infection by Equine Infectious Anemia Virus.
Vaccines    May 27, 2014   Volume 2, Issue 2 397-421 doi: 10.3390/vaccines2020397
Schwartz EJ, Smith RJ.The ability to predict the conditions under which antibodies protect against viral infection would transform our approach to vaccine development. A more complete understanding is needed of antibody protection against lentivirus infection, as well as the role of mutation in resistance to an antibody vaccine. Recently, an example of antibody-mediated vaccine protection has been shown via passive transfer of neutralizing antibodies before equine infectious anemia virus (EIAV) infection of horses with severe combined immunodeficiency (SCID). Viral dynamic modeling of antibody protection from EIAV ...