Veterinary ophthalmology.
Periodical
Ophthalmology
Veterinary Medicine
Eye Diseases
Publisher:
Blackwell Science,
Frequency: Six no. a year, 2004-
Country: England
Language: English
Author(s):
American College of Veterinary Ophthalmologists.
Start Year:1998 -
ISSN:
1463-5216 (Print)
1463-5224 (Electronic)
1463-5216 (Linking)
1463-5224 (Electronic)
1463-5216 (Linking)
Impact Factor
1.6
2022
| NLM ID: | 100887377 |
| (OCoLC): | 41092864 |
| LCCN: | sn 99003713 |
| Classification: | W1 VE933T |
Immunohistochemistry of the extracellular matrix of the normal equine lamina cribrosa.
Veterinary ophthalmology
June 9, 2001
Volume 3, Issue 2-3 127-132 doi: 10.1046/j.1463-5224.2000.00127.x
Brooks DE, Komaromy AM, Garcia-Fernandez MC, Cutler TJ, Samuelson DA, Kallberg ME.Purpose To use immunohistochemical techniques to identify and localize the structural macromolecules of the extracellular matrix (ECM) of the normal adult equine lamina cribrosa in order to make comparisons to the extracellular matrix of the lamina cribrosa of horses with glaucoma. METHODS: Normal eyes of five adult horses between 5 and 10 years of age were fixed in 10% neutral buffered formalin and embedded in paraffin. Polyclonal rabbit-derived antibodies against human elastin, laminin, fibrillin-1, and collagen types I, III and IV, and polyclonal goat-derived antibodies against collagen typ... Disease of the equine posterior segment.
Veterinary ophthalmology
June 9, 2001
Volume 3, Issue 2-3 73-82 doi: 10.1046/j.1463-5224.2000.00138.x
Cutler TJ, Brooks DE, Andrew SE, Denis HM, Biros DJ, Gelatt KN, Komaromy AM, Kallberg M.The appearance of the equine fundus is reviewed from the perspective of differentiating normal variations from disease, and the descriptions have been updated to include recently published ocular fundic abnormalities. Most pathological lesions are identified near the optic nerve head, and typically involve depigmentation or hyperpigmentation. Depending upon configuration and appearance, linear pigmented bands may reflect the course of the vortex veins, the transition from tapetal to nontapetal fundus, or indicate chorioretinitis or equine motor neuron disease. Choroidal vasculature is readily ... Effects of growth factors (EGF, PDGF-BB and TGF-beta 1) on cultured equine epithelial cells and keratocytes: implications for wound healing.
Veterinary ophthalmology
September 3, 2003
Volume 6, Issue 3 211-217 doi: 10.1046/j.1463-5224.2003.00296.x
Haber M, Cao Z, Panjwani N, Bedenice D, Li WW, Provost PJ.The physiologic mechanisms involving growth factors, including PDGF-BB, EGF, and TGF-beta 1, as potent mediators of fibroblasts and epithelial cells in corneal wound healing remain unknown. The goal of this study was to determine culture methods for equine epithelial cells and keratocytes and to investigate how exogenous growth factors influence proliferation of both cell types. Methods: Cell cultures were established from healthy corneas harvested from horses immediately following euthanasia and maintained using standard tissue culture protocols. To determine the effects of PDGF-BB, EGF, TGF-... Read More
32
Conjunctival bacterial and fungal flora in healthy horses in the UK.
Veterinary ophthalmology
April 28, 2011
Volume 14, Issue 3 195-199 doi: 10.1111/j.1463-5224.2010.00867.x
Johns IC, Baxter K, Booler H, Hicks C, Menzies-Gow N.To describe the bacterial and fungal flora of the normal conjunctiva of horses in the UK; to determine the effect of horse age, sex, geographic location, and housing on this flora; and to determine the most appropriate antimicrobial drug(s) for prophylactic treatment of corneal ulcers. Methods: A total of 60 adult healthy horses were studied. Methods: Swabs of the conjunctiva were obtained from 60 horses housed in two locations within the UK. Specimens were cultured for aerobic bacteria and fungi, and sensitivity against six ophthalmic antimicrobials assessed. The effect of age, sex, location ... Read More
24
Comparative morphological evaluation of domestic animal cornea.
Veterinary ophthalmology
July 20, 2015
Volume 19, Issue 4 297-304 doi: 10.1111/vop.12298
Nautscher N, Bauer A, Steffl M, Amselgruber WM.This study described corneal morphology in different domestic animals using histological and immunohistochemical methods. Specifically, we evaluated the species-specific distribution pattern of cytokeratins (CKs) and aquaporins (AQPs) to assess their contribution to the strength and transparency of the cornea, respectively. Methods: Corneal sections (2 μm thick) were obtained from 28 pigs, 11 cows, two goats, six horses, four dogs, and five cats and stained with hematoxylin-eosin and periodic acid-Schiff (PAS) reaction. Immunohistochemistry was also performed using CK1 to 3 and AQP1 and 5 an... Read More
23
Septic keratitis in dogs, cats, and horses in Switzerland: associated bacteria and antibiotic susceptibility.
Veterinary ophthalmology
May 29, 2017
Volume 21, Issue 1 66-75 doi: 10.1111/vop.12480
Suter A, Voelter K, Hartnack S, Spiess BM, Pot SA.To evaluate the most common bacterial pathogens associated with septic keratitis in veterinary patients from Switzerland. The second objective was to analyze antibiotic susceptibility test results of the identified bacterial pathogens. The third objective was to evaluate potential breed predispositions to septic keratitis. Methods: Two hundred and fifty-five cultures and antibiotic susceptibility reports from dogs, cats, and horses with septic keratitis that were presented to the University of Zurich Veterinary Medical Teaching Hospital between 2009 and 2013 were reviewed. Odds ratios for the ... Read More
22
Clinical and electroretinographic characteristics of congenital stationary night blindness in the Appaloosa and the association with the leopard complex.
Veterinary ophthalmology
November 1, 2007
Volume 10, Issue 6 368-375 doi: 10.1111/j.1463-5224.2007.00572.x
Sandmeyer LS, Breaux CB, Archer S, Grahn BH.To determine the prevalence of congenital stationary night blindness (CSNB) in Appaloosa horses in western Canada, investigate the association with the leopard complex of white spotting patterns, and further characterize the clinical and electroretinographic aspects of CSNB in the Appaloosa. Methods: Three groups of 10 Appaloosas were studied based on coat patterns suggestive of LpLp, Lplp, and lplp genotype. Methods: Neurophthalmic examination, slit-lamp biomicroscopy, indirect ophthalmoscopy, measurement of corneal diameter, streak retinoscopy, scotopic and photopic full-field and flicker ER... Read More
21
Seasonal effects on the aerobic bacterial and fungal conjunctival flora of normal thoroughbred brood mares in Florida.
Veterinary ophthalmology
March 19, 2003
Volume 6, Issue 1 45-50 doi: 10.1046/j.1463-5224.2003.00265.x
Andrew SE, Nguyen A, Jones GL, Brooks DE.To evaluate seasonal effects on the presence or absence of fungal and aerobic bacterial flora of the conjunctival fornix of normal Florida Thoroughbred horses. Methods: Both eyes of 100 horses. Methods: Horses with normal anterior segment ophthalmic examinations from three farms in north central Florida were included. Each animal had the ventral conjunctival fornix of each eye swabbed with sterile culturettes. Samples were taken in October, January, April, and July (1999-2000). Aerobic and fungal cultures were plated. Bacterial cultures were reviewed at 24 and 48 h. Fungal cultures were review... Read More
19
The use of porcine small intestinal submucosa for the repair of full-thickness corneal defects in dogs, cats and horses.
Veterinary ophthalmology
August 18, 2004
Volume 7, Issue 5 352-359 doi: 10.1111/j.1463-5224.2004.04055.x
Bussieres M, Krohne SG, Stiles J, Townsend WM.To evaluate the efficacy of using a porcine small intestinal submucosa (SIS) graft covered by a conjunctival flap for the surgical repair of full-thickness corneal wounds in dogs, cats and horses. Methods: All records dating from August 1999 to February 2003 from Purdue University Veterinary Teaching Hospital of patients that had undergone ophthalmic surgical procedures and received a SIS corneal graft for a full-thickness lesion were reviewed. Fifteen cases were identified including six dogs, two cats and seven horses. Requirements for inclusion in this study were that SIS was used as a corne... Read More
19
Suberoylanilide hydroxamic acid (vorinostat): its role on equine corneal fibrosis and matrix metalloproteinase activity.
Veterinary ophthalmology
August 16, 2014
Volume 17 Suppl 1 61-68 doi: 10.1111/vop.12129
Donnelly KS, Giuliano EA, Sharm A, Mohan RR.To explore the effect of suberoylanilide hydroxamic acid (SAHA) (i) on corneal fibroblast differentiation, morphology, and viability; and (ii) on the expression levels of matrix metalloproteinases (MMPs) 2 and 9 using an in vitro model of equine corneal fibrosis. Methods: Healthy donor corneas were used to generate primary cultures of equine corneal fibroblasts. The fibroblasts were exposed to 5 ng/mL TGFβ1 to induce myofibroblast formation. The cultures were treated with either 5 μm or 10 μm SAHA for 72 h in the presence of TGFβ1. Real-time PCR and immunocytochemistry were used to determi... Read More
19
Decorin-PEI nanoconstruct attenuates equine corneal fibroblast differentiation.
Veterinary ophthalmology
May 30, 2013
Volume 17, Issue 3 162-169 doi: 10.1111/vop.12060
Donnelly KS, Giuliano EA, Sharma A, Tandon A, Rodier JT, Mohan RR.To explore (i) the potential of polyethylenimine (PEI) nanoparticles as a vector for delivering genes into equine corneal fibroblasts (ECFs) using green fluorescent protein (GFP) marker gene, (ii) whether PEI nanoparticle-mediated decorin (DCN) gene therapy could be used to inhibit fibrosis in the equine cornea using an in vitro model. Methods: Polyethylenimine-DNA nanoparticles were prepared at nitrogen-to-phosphate (N-P) ratio of 15 by mixing 22 kDa linear PEI and a plasmid encoding either GFP or DCN. ECFs were generated from donor corneas as previously described. Initially, GFP was introduc... Read More
19
Correlation between corneal sensitivity and quantity of reflex tearing in cows, horses, goats, sheep, dogs, cats, rabbits, and guinea pigs.
Veterinary ophthalmology
October 15, 2012
Volume 16, Issue 4 251-262 doi: 10.1111/j.1463-5224.2012.01069.x
Wieser B, Tichy A, Nell B.Guinea pigs have a very low threshold of corneal sensitivity and at the same time nearly no reflex tearing compared to dogs, cats, and horses. The question arose whether there is a general correlation between corneal sensitivity and the quantity of reflex tearing. Methods: Totally 160 animals of 8 different species (20 animals per species) were investigated. Methods: The corneal touch threshold (CTT) was measured with a Cochet-Bonnet esthesiometer. The palpebral fissure length (PFL) was measured with a calliper ruler. The Schirmer tear test (STT) was modified by adapting the width of the STT s... Read More
18
Congenital ocular abnormalities of Rocky Mountain Horses.
Veterinary ophthalmology
June 9, 2001
Volume 2, Issue 1 47-59 doi: 10.1046/j.1463-5224.1999.00050.x
Ramsey DT, Ewart SL, Render JA, Cook CS, Latimer CA.OBJECTIVE: To determine the incidence and describe ocular abnormalities in a cross-section of the population of Rocky Mountain Horses. Design: Prospective study. Animals: Five-hundred and fourteen Rocky Mountain Horses. Procedure: Ophthalmic examinations were performed using a slit-lamp biomicroscope and an indirect ophthalmoscope. Intraocular pressures were measured by applanation tonometry. Eyes from six horses were obtained for histologic examination. RESULTS: Cysts of the posterior iris, ciliary body, and peripheral retina were detected most frequently (249 horses), and were always located... Read More
18
Ulcerative keratitis in thoroughbred racehorses in Japan from 1997 to 2008.
Veterinary ophthalmology
May 8, 2010
Volume 13, Issue 2 99-105 doi: 10.1111/j.1463-5224.2010.00767.x
Wada S, Hobo S, Niwa H.To describe the number of cases, etiologies, healing times, and results of microbial culture and susceptibility testing of corneal ulcers in thoroughbred racehorses in Japan. Methods: Retrospective study of the medical records of racehorses belonging to the Japan Racing Association (JRA) from 1997 to 2008. Results: A total of 2846 horses suffered ulcerative keratitis. These horses accounted for 90.5% of all the corneal problems and 54.9% of the entire number of horses with ocular diseases. Running in races was the cause in 64.3% of the cases. The mean healing time of the ulcers developed in ra... Read More
18
Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro.
Veterinary ophthalmology
August 22, 2019
Volume 23, Issue 1 160-170 doi: 10.1111/vop.12704
Saldinger LK, Nelson SG, Bellone RR, Lassaline M, Mack M, Walker NJ, Borjesson DL.Equine recurrent uveitis (ERU) is an immune-mediated disease causing repeated or persistent inflammatory episodes which can lead to blindness. Currently, there is no cure for horses with this disease. Mesenchymal stem cells (MSCs) are effective at reducing immune cell activation in vitro in many species, making them a potential therapeutic option for ERU. The objectives of this study were to define the lymphocyte phenotype of horses with ERU and to determine how MSCs alter T-cell phenotype in vitro. Whole blood was taken from 7 horses with ERU and 10 healthy horses and peripheral blood mononuc... Read More
17
Characterization of cytokines associated with Th17 cells in the eyes of horses with recurrent uveitis.
Veterinary ophthalmology
October 7, 2011
Volume 15, Issue 3 145-152 doi: 10.1111/j.1463-5224.2011.00951.x
Regan DP, Aarnio MC, Davis WS, Carmichael KP, Vandenplas ML, Lauderdale JD, Moore PA.Equine recurrent uveitis (ERU) is a spontaneous disease that is the most common cause of blindness in horses, affecting up to 15% of the horse population. Th17 cells are a major cell population driving the pathogenesis in several mouse models of autoimmune inflammation, including experimental autoimmune uveitis. The purpose of this study is to investigate the role a Th17 cell-mediated response plays in the pathogenesis of ERU. Methods: Banked, Davidson's-fixed equine globes histopathologically diagnosed with ERU (n = 7) were compared immunohistochemically with healthy control globes (n = 7). I... Read More
17
Isolation and cultivation of equine corneal keratocytes, fibroblasts and myofibroblasts.
Veterinary ophthalmology
February 13, 2010
Volume 13, Issue 1 37-42 doi: 10.1111/j.1463-5224.2009.00755.x
Buss DG, Giuliano EA, Sharma A, Mohan RR.To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was developed. ANIMAL MATERIAL: Equine corneal buttons were aseptically harvested from healthy research horses undergoing humane euthanasia for reasons unrelated to this study. Slit-lamp biomicroscopy was performed prior to euthanasia by a board-certified veterinary ophthalmologist to ensure that all samples were harvested from horses free of anterior segment disease. Methods: Equine corneal s... Read More
16
Long-term outcome after implantation of a suprachoroidal cyclosporine drug delivery device in horses with recurrent uveitis.
Veterinary ophthalmology
September 16, 2010
Volume 13, Issue 5 294-300 doi: 10.1111/j.1463-5224.2010.00807.x
Gilger BC, Wilkie DA, Clode AB, McMullen RJ, Utter ME, Komaromy AM, Brooks DE, Salmon JH.To determine the long-term efficacy, complications, and duration of effect of a cyclosporine (CsA) suprachoroidal implant (CSI) in horses with equine recurrent uveitis (ERU). Methods: Horses with ERU were treated with a 6-mm diameter, 25 mg, reservoir matrix CsA implant in the deep sclera adjacent to the suprachoroidal space. Horses with follow-up >1 year were examined for frequency of uveitis episodes, complications, and vision at last recheck. Results: Data from 151 eyes of 133 horses from the USA and Europe that had CsA devices implanted for ERU were reviewed. Follow-up time ranged from 13 ... Read More
16
Changes in antibiotic resistance in equine bacterial ulcerative keratitis (1991-2000): 65 horses.
Veterinary ophthalmology
December 3, 2003
Volume 6, Issue 4 309-313 doi: 10.1111/j.1463-5224.2003.00312.x
Sauer P, Andrew SE, Lassaline M, Gelatt KN, Denis HM.To document changes in antibiotic resistance of organisms in cases of equine bacterial ulcerative keratitis over a 10-year time period. Methods: A retrospective study. Methods: Medical records of equine patients with bacterial ulcerative keratitis seen at the University of Florida's VMTH for the years 1991-2000 were reviewed. Methods: All cases of equine bacterial ulcerative keratitis for the above mentioned years were examined. Bacterial isolates were identified and subjected to Kirby-Bauer disc diffusion method sensitivity tests. Antibiotics used in the sensitivity tests included bacitracin,... Read More
16
Subconjunctival bone marrow-derived mesenchymal stem cell therapy as a novel treatment alternative for equine immune-mediated keratitis: A case series.
Veterinary ophthalmology
February 4, 2019
Volume 22, Issue 5 674-682 doi: 10.1111/vop.12641
Davis AB, Schnabel LV, Gilger BC.Equine immune-mediated keratitis (IMMK) leads to increased corneal opacity and inflammation secondary to an alteration of the local immune system. Bone marrow-derived mesenchymal stem cells (BM-MSC) have been shown to modulate the immune system by downregulating inflammation. Four horses with unilateral IMMK poorly responsive to traditional medical treatments underwent novel, autologous subconjunctival BM-MSC therapy. Bone marrow was harvested and processed as previously described for equine orthopedic disease. Horses received autologous subconjunctival BM-MSC injections approximately every 3-... Read More
16
Diagnosis of Borrelia-associated uveitis in two horses.
Veterinary ophthalmology
February 23, 2012
Volume 15, Issue 6 398-405 doi: 10.1111/j.1463-5224.2012.01000.x
Priest HL, Irby NL, Schlafer DH, Divers TJ, Wagner B, Glaser AL, Chang YF, Smith MC.Borrelia burgdorferi, the etiologic agent of Lyme disease is a tick born spirochetal infection. Clinical signs of Lyme borreliosis are uncommon in horses, but when present they are often vague and nonspecific. In horses, Lyme borreliosis has been implicated in musculoskeletal, neurological, reproductive, and ocular disorders, including uveitis, but definitive diagnosis can be challenging as the causative agent is rarely isolated and serologic tests can be unreliable and do not confirm active disease. Here, we report two cases of equine uveitis associated with B. burgdorferi based on the identi... Read More
16
The diagnosis and treatment of periorbital sarcoid in the horse: 445 cases from 1974 to 1999.
Veterinary ophthalmology
June 9, 2001
Volume 3, Issue 2-3 169-191 doi: 10.1046/j.1463-5224.2000.00119.x
Knottenbelt DC, Kelly DF.OBJECTIVE: Diagnosis and management of periorbital sarcoids in horses is a significant clinical challenge for the practicing veterinary surgeon and pathologist. The purpose of this study was to investigate the response of various types of sarcoids to different therapeutic methods. Animals studied Medical records of 445 clinical patients. Procedures This paper retrospectively examines the clinical and histological features of periorbital sarcoids and the treatment of 445 cases. Treatment by surgical excision, cryosurgery, Bacillus-Calmette-Gaérin (BCG) immunomodulation, topical cytotoxic appli... Read More
15
Therapeutic potential of Pirfenidone for treating equine corneal scarring.
Veterinary ophthalmology
July 15, 2014
Volume 18, Issue 3 242-250 doi: 10.1111/vop.12194
Fink MK, Giuliano EA, Tandon A, Mohan RR.To evaluate the safety and efficacy of Pirfenidone (PFD) in the treatment of equine corneal fibrosis using an in vitro model. Methods: Healthy donor equine corneas were collected and used to generate primary equine corneal fibroblasts (ECFs) by growing cultures in minimal essential medium supplemented with 10% fetal bovine serum. Equine corneal myofibroblasts (ECMs), used as a model of equine corneal fibrosis, were produced by growing ECF cultures in serum-free medium containing transforming growth factor β1 (1 ng/mL). Trypan blue viability assays and changes in ECF morphology were utilized t... Read More
14
Corneal stromal invasive squamous cell carcinoma: a retrospective morphological description in 10 horses.
Veterinary ophthalmology
January 21, 2009
Volume 12, Issue 1 6-12 doi: 10.1111/j.1463-5224.2009.00666.x
Kafarnik C, Rawlings M, Dubielzig RR.To describe the pathomorphological features of corneal stromal invasive squamous cell carcinoma (CSI-SCC) in horses. Methods: A total of 87 equine SCC in the Comparative Ocular Pathology Laboratory of Wisconsin database were retrieved. The signalment and anatomical distribution were summarized. Ten CSI-SCC out of 87 SCCs were further investigated focusing on pathomorphological description. All 10 cases were stained with H&E, periodic acid-Schiff stain and Verhoeff's elastic stain. Results: Four Appaloosas, two Quarter horses, two American Paint, one Pinto and one Thoroughbred horse were affect... Read More
14
Risk factors for equine recurrent uveitis in a population of Appaloosa horses in western Canada.
Veterinary ophthalmology
February 22, 2020
Volume 23, Issue 3 515-525 doi: 10.1111/vop.12749
Sandmeyer LS, Kingsley NB, Walder C, Archer S, Leis ML, Bellone RR, Bauer BS.To characterize clinical manifestations, measure frequency, and evaluate risk factors for equine recurrent uveitis (ERU) in Appaloosa horses in western Canada. Methods: 145 Appaloosa horses. Methods: Ophthalmic examinations were completed and eyes were classified as having no or mild clinical signs, or moderate, or severe damage from ERU. Clinical signs, age, sex, base coat color, and pattern were recorded. Whole blood and/or mane hair follicles were collected for DNA extraction, and all horses were tested for the leopard complex (LP) spotting pattern allele. Pedigree analysis was completed on... Read More
13
Ocular immunology in equine recurrent uveitis.
Veterinary ophthalmology
December 17, 2008
Volume 11 Suppl 1 61-65 doi: 10.1111/j.1463-5224.2008.00625.x
Deeg CA.Equine recurrent uveitis (ERU) is a disease with high prevalence and relevance for the equine population, since it results in blindness. Over the last decade, important advancements have been made in our understanding of the underlying immune responses in this disease. ERU is mediated by an autoaggressive Th1 response directed against several retinal proteins. Interphotoreceptor-retinoid binding protein (IRBP) and cellular retinaldehyde-binding protein (CRALBP) are capable to induce ERU-like disease in experimental horses, with the unique possibility to activate relapses in a well-defined mann... Read More
13
Using minimum inhibitory concentration values of common topical antibiotics to investigate emerging antibiotic resistance: A retrospective study of 134 dogs and 20 horses with ulcerative keratitis.
Veterinary ophthalmology
July 1, 2020
Volume 23, Issue 5 806-813 doi: 10.1111/vop.12801
Jinks MR, Miller EJ, Diaz-Campos D, Mollenkopf DF, Newbold G, Gemensky-Metzler A, Chandler HL.To identify the minimum inhibitory concentration (MIC) distribution for commonly used topical antibiotics from isolates of dogs and horses with ulcerative bacterial keratitis, and to investigate changes in MIC values over time and following treatment with topical fluoroquinolones. Methods: One hundred thirty-four client-owned dogs and 20 client-owned horses with bacterial ulcerative keratitis. Methods: Minimum inhibitory concentration values for 14 topical antibiotics were reported for canine and equine cases of bacterial ulcerative keratitis between 2013 and 2018. Changes in MIC values over t... Read More
12
The use of amniotic membrane transplantation for ocular surface reconstruction: a review and series of 58 equine clinical cases (2002-2008).
Veterinary ophthalmology
November 26, 2009
Volume 12 Suppl 1 17-24 doi: 10.1111/j.1463-5224.2009.00741.x
Plummer CE, Ollivier F, Kallberg M, Brooks D, Barrie K, Utter M, Gelatt K.Amniotic membrane transplantation (AMT) is an effective clinical therapy for reconstruction of the ocular surface in human and veterinary patients. Amnion is avascular and strong, contains antiangiogenic and antiinflammatory properties and growth factors, and has properties that prevent or decrease fibrosis in healing tissue. Indications for its use are steadily growing and include grafting to replace diseased, missing or excised tissue, patching to support diseased tissue during the healing process and as a substrate for the expansion of epithelial cells for transplantation to the cornea. AMT... Read More
12
Identification of bacteria and fungi sampled from the conjunctival surface of normal horses in South-East Queensland, Australia.
Veterinary ophthalmology
July 2, 2018
Volume 22, Issue 3 265-275 doi: 10.1111/vop.12587
Hampson ECGM, Gibson JS, Barot M, Shapter FM, Greer RM.To identify bacteria and fungi found on the conjunctival surface of normal horse eyes; to investigate potential risk factors for these microflora; and to determine their susceptibility to common topical ophthalmic antimicrobials. Methods: A total of 95 client-owned horses were studied. Methods: Horses within sub-tropical Australia (South-East Queensland) were sampled once between April 2012 and March 2013. A conjunctival swab was taken from each eye and cultured for aerobic bacteria and fungi. Organisms were identified by colony morphology and phenotype. Antimicrobial disk diffusion susceptibi... Read More
12
In vitro susceptibility patterns of Aspergillus and Fusarium species isolated from equine ulcerative keratomycosis cases in the midwestern and southern United States with inclusion of the new antifungal agent voriconazole.
Veterinary ophthalmology
September 16, 2009
Volume 12, Issue 5 318-324 doi: 10.1111/j.1463-5224.2009.00721.x
Pearce JW, Giuliano EA, Moore CP.To evaluate and compare the in vitro susceptibility of Aspergillus and Fusarium spp. isolated from horses with ulcerative keratomycosis, address regional differences in equine keratomycosis isolates, and provide susceptibility data to update prior studies. Methods: Fourteen horses with ulcerative keratomycosis. Methods: Banked fungal isolates from equine corneal ulcers (eight Aspergillus spp. and six Fusarium spp.) were identified at The University of Texas Health Science Center at San Antonio. In vitro minimum inhibitory concentration and susceptibility to natamycin, fluconazole, itraconazole... Read More
12
Schirmer tear test results in normal horses and ponies: effect of age, season, environment, sex, time of day and placement of strips.
Veterinary ophthalmology
September 3, 2003
Volume 6, Issue 3 251-254 doi: 10.1046/j.1463-5224.2003.00302.x
Beech J, Zappala RA, Smith G, Lindborg S.Tear production was evaluated in 39 horses and 29 ponies using Schirmer tear test strips to determine whether diurnal or weekly fluctuations occur, whether location of strip placement has an effect, if values are the same for both eyes in an animal and whether sex, age, stabling vs. pasture and winter vs. summer had an effect. There was no test in which the raw score was less than 10 mm, although there were many occasions where tear wetting exceeded 35 mm. Analysis of the raw (continuous) scores by linear regression provided no evidence that signalment, housing or season or location of strip p... Read More
12
Equine glaucoma: a histopathologic retrospective study (1999-2012).
Veterinary ophthalmology
July 16, 2013
Volume 17, Issue 5 334-342 doi: 10.1111/vop.12080
Curto EM, Gemensky-Metzler AJ, Chandler HL, Wilkie DA.To characterize and describe the histopathologic findings in equine globes enucleated due to glaucoma. Methods: Medical records at The Ohio State University from 1999 to 2012 were reviewed retrospectively. Signalment, history, and treatment data were collected, and histologic slides of enucleated globes were examined and lesions recorded. Twenty-three eyes from 23 horses were eligible for inclusion in this study. Results: The majority of affected horses were > 15 years of age (65%). The ages ranged from 5 to 35 years (mean = 17.4 years). The left eye was affected in 10 cases (43%) and the righ... Read More
12