Topic:Cancer
Cancer in horses encompasses a range of neoplastic diseases that affect various tissues and organs in equine species. These conditions involve the uncontrolled growth of abnormal cells, which can form tumors and potentially spread to other parts of the body. Common types of cancer in horses include sarcoids, squamous cell carcinoma, and melanoma, each with distinct characteristics and clinical presentations. Diagnosis often involves a combination of physical examination, imaging techniques, and histopathological analysis. Treatment options vary based on the type and stage of cancer and may include surgical intervention, chemotherapy, and radiation therapy. This page compiles peer-reviewed research studies and scholarly articles that explore the epidemiology, pathophysiology, diagnostic methods, and treatment strategies for cancer in horses.
Cryotherapy of periocular squamous cell carcinoma in the horse. Squamous cell carcinoma around the eyes of 3 horses was treated with liquid nitrogen, using cryotherapy probes as the method of application. In 2 cases, there was complete regression of the tumor; in the 3rd case, remission and relief of discomfort were temporary.
Neoplasms of Equidae. In a retrospective study of neoplasms in Equidae pre;ented to the Animal Disease Diagnostic Laboratory, Purdue University, from Jan 1, 1970, to Dec 31, 1974, data were compiled on numbers and anatomic sites of neoplasms as well as on age, sex, and breed of subjects from which the neoplasms were taken. During this 5-year period, 21 neoplasms were diagnosed from 687 equine necropsies (3.1%) and 215 from 635 biopsies (33.9%), totaling 236 neoplasms from 1,322 cases (17.9%). The most common neoplasms were sarcoids (43.6%) and squamous cell carcinomas (24.6%). Papillomas (5.5%), nerve sheath tumors...
A general survey of tumours in the horse. Published figures from veterinary schools indicate that tumours may account for about 1 to 3 per cent of surgical cases. In this paper an account is given of clinical and pathological aspects of the tumours that are most likely to be encountered in practice, either as visibly or palpably detectable masses of tissue, or as internal tumours responsible for clinical signs. Amongst the common and important tumours dealt with, the most prominent are "equine sarcoid", squamous-cell carcinoma (of eye region and of glans penis), granulosa-cell tumours and melanomas. Well over a hundred references prov...
Epidemiologic analysis of oral and pharyngeal cancer in dogs, cats, horses, and cattle. Four hundred sixty-nine oral-pharyngeal malignancies diagnosed in dogs, cats, horses, and cattle and submitted to the Viterinary Medical Data Program between March 1, 1964, and Dec 31, 1974, were analyzed. Of these cases, 84% were in dogs. The most frequent oral-pharyngeal cancer in dogs was melanoma; in cats and horses, it was squamous cell carcinoma. In dogs, the risk of developing melanoma increased more with age than did the risk of developing squamous cell carcinoma and fibrosarcoma. Male dogs had significantly greater risk of developing fibrosarcomas and melanomas than did female dogs. T...
Cryosurgical treatment of cancerous and noncancerous diseases of dogs, horses, and cats. Cryosurgery was used to treat a variety of cancerous and noncancerous diseases in dogs, horses, and cats. Follow-up evaluation on 52 animals revealed an overall "no recurrence" rate of 61%. Among the animals with no recurrence were 12 of 17 with cutaneous lesions and 5 of 8 (horses) with sarcoids. Seven of 10 dogs with anal fistulas healed after cryosurgery, but 2 had recurrence of the disease. Treatment of invasive neoplasms of the oral and nasal cavities was not successful. Side effects and complications were minimal.
[Dyspnoea due to intrathoracic haemorrhage and haemangiosarcoma in a horse (author’s transl)]. Post-morten examination of a fourteen-year-old mare of the Gelderland breed, which had been treated for severe dyspnoea and had subsequenlty died, revealed the presence of haemothorax, atelectasis of the lung and a metastasized haemangiosarcoma of the left ovary. The haemothorax could have resulted from rupture of one of the metastases.
Radiotherapy of spontaneous fibrous connective-tissue sarcomas in animals. The clinical records and follow-up data obtained over 13 years on the results of radiotherapy of spontaneous fibrous connective-tissue sarcomas in dogs, cats, and horses were reviewed. The results obtained from the treatment of fibrosarcomas and sarcoids of horses indicated that radiation administered with 60Co is important in the medical and surgical management of these tumors. Fibrous connective-tissue sarcomas in horses were radioresponsive. When radiotherapy was applied postoperatively, the probability of a 2-year cure approached 50% for all prescribed radiation doses of less than 2,000 to...
Squamous cell carcinoma in horses. In a review of neoplasm registry records at Kansas State University (1961 through 1971), 58 squamous cell carcinomas were reported in 10 breeds of horses. Mean age of the affected horses was 12.4 years. The head, eye and ocular adnexa accounted for 43.1%, the external male genitalia, 44.8%, and female perineal region, 12.0% of the squamous cell carcinomas, altogether representing 20.2% of 287 neoplasms recorded.
Tumours of the prostate and penis. Tumours of the male genital tract, excluding the testes, are relatively rare in the six major domestic animals. The most important tumours are prostate carcinoma and transmissible venereal tumour of the penis in dogs, fibropapilloma of the penis in bulls, squamous papilloma and squamous cell carcinoma in horses, and squamous papilloma in pigs. Four histological types of canine prostate carcinoma exist: alveolar papillary, acinar, organoid, and poorly differentiated. The biological behaviour of prostate carcinomas is similar to that in man, with frequent metastasis to the regional pelvic nodes,...
Histological survey of tumours of the horse, with particular reference to those ofthe skin. In a histological survey of 244 tumerous growths from 155 horses, the tumours commonly found were fibromas, squamous cell carcinomas, sarcoids and papillomas, most frequently affecting the skin, external genitalia, eye and orbit. The histological features that differentiate fibroblastic citaneous growths are detailed so that the clinical behaviour of these distinct neoplasms can be studied.
Giant cell tumor of soft parts. A report of an equine and a feline case. Masses removed from the superficial fascia of the jugular groove of a 12-year-old Arabian mare and from the femoral canal of a 7 1/2-year-old female cat appeared to be counterparts of the human malignant giant cell tumor of soft parts, even recapitulating the clinical behavior of the respective subgroups. Histologically, both neoplasms contained the characteristic features of the malignant giant cell tumor of soft parts: large multinucleate giant cells, pleomorphic mononuclear giant cells, histiocytes, fibroblasts and fibrocytes that were sometimes sarcomatous, and foci of hemorrhage and necro...
Primary ocular melanoma in a young horse. The clinical features and pathology of an ocular melanoma in a young born-grey mare are described. The tumour, possibly arising on the cornea, invaded the eye and extra-orbital muscles. Histologically; it consisted predominantly of spindle-shaped and polygonal cells containing melanin.