Topic:Cholelithiasis
Cholelithiasis in horses refers to the formation of gallstones within the biliary system, which includes the liver, gallbladder, and bile ducts. These stones are typically composed of cholesterol, bilirubin, or a combination of substances. Cholelithiasis can lead to biliary obstruction, causing symptoms such as colic, jaundice, and weight loss in affected horses. Diagnosis is often achieved through ultrasonography or other imaging techniques, alongside blood tests to assess liver function. Treatment may involve medical management or surgical intervention, depending on the severity and location of the stones. This page compiles peer-reviewed research studies and scholarly articles that explore the pathophysiology, diagnosis, and management of cholelithiasis in equine patients.
Ultrasound of the equine acute abdomen. Abdominal ultrasound is an invaluable aid in the evaluation of the colic patient but can be heavily influenced by patient preparation, individual horse-to-horse variation, availability of ultrasound transducers, technique, experience level of the examiner, and complexity of the abdominal disorder. This article describes ultrasonographic anatomy of the normal equine abdomen and technique for examination of the equine colic patient. Common abnormalities of the stomach, small intestine, large intestine, and peritoneal cavity are described along with other abnormalities that may be discovered with...
Cholelithiasis associated with recurrent colic in a Thoroughbred mare. A 13-year-old Thoroughbred mare, retired from race, was admitted to Equine Hospital, Korea Racing Association with signs of colic. One and a half months following the previous treatment (second time) and 11 days following her previous discharge (third time), the mare repeatedly exhibited signs of colic and finally along with icteric eyes. Routine medical treatment with intravenous fluids, analgesics resulted in resolution of signs of colic in the first and second admission. The condition of the mare did not improve in the third admission despite over one month supportive treatment and she was ...
Medical treatment of cholangiohepatitis and cholelithiasis in mature horses: 9 cases (1991-1998). The medical approach to treatment of cholangiohepatitis and cholelithiasis in 9 horses is described. Seven horses were treated successfully and returned to normal use, with a minimum follow-up period of 12 months. Long-term antimicrobial therapy was believed to be critical in those cases that survived, with a median treatment duration of 51 days (range 17-124 days). Treatment failure was associated with severe periportal and bridging hepatic fibrosis from biopsy material obtained at admission in 2 horses, one of whom also presented with hyperammonaemic hepatic encephalopathy. Transabdominal ul...
Ultrasonographic findings in horses with cholelithiasis: eight cases (1985-1987). Cholelithiasis and/or obstructive biliary tract disease was diagnosed ultrasonographically in 8 horses, 5 to 15 years old. Ultrasonographic findings revealed greater than normal amount of hepatic parenchyma in the right side of the abdomen in 8 horses and in the left side in 3 horses. The echogenicity of the liver was greater than normal, and thick distended bile ducts were seen in all horses. Choleliths were imaged ultrasonographically in 6 horses. Subsequently, postmortem findings in 6 horses revealed periportal and intralobular fibrosis, moderate bile duct dilatation, proliferation, and cho...
Cholelithiasis in horses: ten cases (1982-1986). Ten horses with clinical signs consistent with cholelithiasis were evaluated. Fever, icterus, mild intermittent colic, and weight loss were reported. Clinical laboratory abnormalities included leukocytosis, hyper-proteinemia, and hyperfibrinogenemia. Gamma glutamyltransferase and liver isoenzyme of lactate dehydrogenase activities also were high. Choleliths were observed via ultrasonography of the liver in 5 of the 8 horses evaluated, and increased echogenicity of the hepatic parenchyma and dilated bile ducts were observed in all horses. Seven horses were treated medically, 5 of which died or ...
Cholelithiasis in four horses. Four cases of cholelithiasis in horses were reviewed. Two horses were examined because of recurrent abdominal pain. Clinical laboratory data, results of physical examination, and history indicated biliary obstruction. In 1 case, B-mode ultrasonography aided in the diagnosis, which was confirmed at necropsy. In 2 horses, the biliary calculi were incidental necropsy findings.