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Topic:Clinical Study
Clinical studies in equine research involve the systematic investigation of health and disease in horses through structured scientific methods. These studies aim to evaluate the safety and efficacy of treatments, understand disease mechanisms, and improve veterinary care practices. Clinical studies can include randomized controlled trials, observational studies, and case-control studies. They may focus on various aspects such as pharmacokinetics, therapeutic interventions, and diagnostic techniques. This page compiles peer-reviewed research studies and scholarly articles that explore the design, implementation, and findings of clinical studies in equine medicine, providing insights into their impact on horse health and veterinary practices.
A preliminary report on an attempt to modify behavior of untamed ponies by acupuncture. A preliminary study using various acupuncture techniques to modify behavior of untamed ponies was attempted. In five of the seven tested parameters, the animals's behavioral responses were unaffected by acupuncture treatments. However, substantial improvement of general behavior of the nervous ponies was observed in animals treated with jaw and scutiform points. The results are not conclusive and further testing of acupuncture as a mean of modifying animal behavior is desirable.
[Localization of beta-n-acetylhexosaminidase in stallion epididymis (author’s transl)]. The localization of beta-N-acetylhexosaminidase activity in 6 different segments of the epididymis was investigated in 8 stallions using biochemical and histochemical methods. The highest enzyme activity was found in segment D while the other segments displayed a much weaker reaction There was no or only low enzyme activity present in the epididymal fluid of the proximal 3 segments, whereas it was high in the distal 3 segments. The biological function of beta-N-acetylhexosaminidase in the epididymis is discussed briefly.
Comparison of various tests for the serological diagnosis of Trypanosoma equiperdum infection in the horse. Comparative tests such as FAT, ELISA, RIA, IEO and CF in the diagnosis of dourine in the horse have proved a satisfactory concordance ratio of the ELISA with CF, which seems to be the most reliable test. Discrepancies have been observed as to the other tests which appear less sensitive than CF test.
Fatty acid composition of equine plasma. Fatty acid composition of plasma lipids of normal horses was determined. Four fatty acids (C16:0, C18:0, C18:1, and C18:2) comprised 86.73% of the total, with C18:2 comprising 44.04% of the total. Eight other fatty acids were found in small amounts. Unsaturated fatty acids constituted 66% of the total. Marked variation was demonstrated in fatty acid occurrence and distribution in the sterol ester, triglyceride, phospholipid, and free fatty acid fractions.
Concentration of serum transferrin in sick horses and its relationship to serum albumin content. Studies of transferrin (Tf) concentration in sera of sick horses were carried out using Mancini’s immunodiffusion technique. Relative values against a chosen reference serum were determined for a total of 112 horses. Horses with acute infections had Tf values significantly below the normal. The lowest individual Tf value in this group (46%) was found in a six-months-old foal with temperature 41°C and watery diarrhoea. Horses suffering from acute laminitis also had decreased Tf values. The lowest value in the whole material (45%) was found in a horse belonging to this group. There was a posi...
[A serological study of the contagious equine metritis: comparison between indirect immunofluorescence, slow agglutination and complement fixation techniques (author’s transl)]. Serological response of pony mares to contagious equine metritis is studied comparing three techniques: slow agglutination, complement fixation and indirect immunofluorescence. Sera were taken from pony mares vaccinated with a heat inactivated suspension of Haemophilus equigenitalis, from experimentally-infected pony mares and from healthy horses. All three reactions detected antibodies in vaccinated and infected animals. The highest titers are observed with vaccinated mares. Titers are low in infected animals. Antibodies detected by indirect immunofluorescence appeared sooner and persisted lo...
