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Topic:Disease Etiology
Disease etiology in horses refers to the study of the causes and development of diseases within equine populations. It encompasses various factors, including genetic predisposition, environmental influences, infectious agents, and nutritional imbalances, that contribute to the onset and progression of diseases in horses. Understanding disease etiology is essential for identifying risk factors and implementing preventative measures in equine health management. This topic includes research on pathogen-host interactions, the impact of management practices on disease incidence, and the role of genetic and environmental factors in disease susceptibility. This page compiles peer-reviewed research studies and scholarly articles that explore the mechanisms, contributing factors, and implications of disease etiology in horses.
Mucosal alterations in experimentally induced small intestinal strangulation obstruction in ponies. Small intestinal strangulation obstruction (ISO) was produced in seven ponies (under pentobarbital-anesthesia) by arteriovenous ligation. Positive-pressure ventilation with room air was used to maintain arterial PCO2 at the initiation of the ISO. Biopsy materials obtained from affected intestines at various times were evaluated, using histopathologic examination and scanning electron microscopy. Mucosal and villus degeneration was graded 0 to V and compared with intestinal gross color, motility, and wall thickness. The mucosa at the tip of the villus was the first to be affected. Degeneration ...
Salmonellosis in a group of ponies: failure to identify a chronic active carrier. Three of 33 ponies died after the herd had been moved to a new environment 3 months earlier. One mare died without premonitory signs of illness. Shortly thereafter, a 5-day-old foal and a 2-year-old gelding died after brief illness. Although cultures were not performed on the mare, Salmonella typhimurium was isolated from the feces and tissues of the foal and gelding. Lesions in the foal were confined to ecchymotic hemorrhages on the mucosal surface of the colon and petechial hemorrhages in the splenic capsule, with adhesions to the parietal peritoneum. The gelding had evidence of severe typhl...
Toxicoinfectious botulism in foals and adult horses. Toxicoinfectious botulism was proved to be the cause of a neuromuscular paralytic syndrome in foals and adult horses. In eight successive cases, Clostridium botulinum type B was isolated at necropsy. Foals were either found dead without premonitory signs of illness or, most often, they had signs of progressive and symmetric motor paralysis. Stilted gait, muscular tremors, and the inability to stand longer than 4 to 5 minutes were the salient clinical signs. Other clinical manifestations included dysphagia, constipation, mydriasis, and frequent urination. As the disease progressed, dyspnea with...
[Bacteriological studies of Haemophilus equigenitalis Taylor 1978, the causative organism of contagious equine metritis 1977 (author’s transl)]. The cultural, biochemical, antigenic and antibiotic susceptibility characteristics of 17 strains of Haemophilus equigenitalis, the causative organism of contagious equine metritis (CEM), were studied. Biochemical characteristics were investigated using both conventional method and the API ZYM system of enzyme detection. The biochemical profile of the H. equigenitalis strains was unique and differed from the other bacterial species studied under the same experimental conditions (H. influenzae and H. parainfluenzae, B. abortus and B. melitensis, P. multocida, A. calcoaceticus). The required X an...
Epidemiology of equine influenza, risk by age, breed and sex. Three hundred and sixty cases of diagnosed equine influenza reported to the Veterinary
Medical Data Program (VMDP) of the National Cancer Institute, U.S.A., were tested for the
independent effects of age, breed and sex, relative to a reference clinic-hospital population of 84,562
equine patients. Horses of age category 2-6 months showed a significant risk above unity for
infection with equine influenza virus whereas, horses in age category 7-10 yr showed a significant,
low and sparing risk. Horses under two months or over 10 years, as well as those in ages from 6
months to 7 yr had non-s...
[Rhinosporidiosis in the horse. Histological and electron microscopic study of a case]. No abstract available
Eastern equine encephalomyelitis in Panama: the epidemiology of the 1973 epizootic. In late June 1973, a small outbreak of equine encephalitis caused by eastern equine encephalomyelitis (EEE) virus occurred in the Republic of Panama. At least 100 horses were affected by the disease and 40 died. More than 1,700 human sera were obtained from areas of virus activity but no serological evidence for infection was found. Four isolates of EEE virus were recovered, one of which was from a small pool of Culex taeniopus mosquitoes. Serologic studies of infected horses and classification by the short incubation hemagglutination-inhibition tests revealed that these isolates were South Am...
H-Y antigen in a fertile XY female horse. The presence of significantly reduced levels of H-Y antigen in the blood of an XY mare is consistent with the view that H-Y genes comprise a system of testis determinants. Loss or suppression of a critical portion of H-Y genes and subthreshold expression of H-Y antigen could account for a failure of testicular differentiation, thereby allowing a measure of ovarian development in an XY embryo.
