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Topic:Disease Treatment
Disease treatment in horses encompasses a range of medical interventions and management strategies aimed at addressing various health conditions affecting equine species. These treatments can include pharmacological approaches, such as the administration of antibiotics, anti-inflammatory drugs, and antiparasitic medications, as well as non-pharmacological methods like physical therapy, dietary adjustments, and surgical procedures. The selection of appropriate treatments depends on the specific disease, its severity, and the individual needs of the horse. This topic brings together peer-reviewed research studies and scholarly articles that explore the efficacy, safety, and advancements in therapeutic options for equine diseases, providing insights into best practices and emerging trends in equine veterinary medicine.
Indolent-like corneal ulcers in 3 horses. Three horses were admitted with indolent-like corneal ulcers. All horses were treated topically with antibiotics. Two horses had ulcers with redundant epithelial borders, which were debrided with cotton-tipped applicators after topical anesthesia was induced. One ulcer healed after 2 debridements. Of 2 horses treated surgically, one had complications.
Technique for arthroscopic repair of third carpal bone slab fractures in horses. A technique involving internal fixation guided by arthroscopy was used to repair third carpal slab fractures in 23 horses. The technique allowed good reduction and compression of the fractures, with minimal surgical trauma. Ten of 17 horses with a 6-month or longer follow-up have returned to race successfully.
Fenbendazole in equids: further controlled tests with emphasis on activity of multiple doses against naturally occurring infections of migratory large strongyles. Two controlled tests (experiments D and E) were done to evaluate a fenbendazole (FBZ) paste dosage regimen (10 mg/kg once a day for 5 days) for activity against naturally occurring infections of migrating Strongylus vulgaris and S edentatus in the mesenteric arteries and ventral abdominal wall, respectively. Data were also obtained on other internal parasites of the gastrointestinal tract and eyes in experiment E. Eight pony yearlings were used in experiment D (4 treated and 4 nontreated) and 6 horse weanlings were used in experiment E (3 treated and 3 nontreated). Intervals, expressed as days...
Risk factors for salmonellosis in hospitalized horses. A case-control study to identify risk factors associated with isolation of Salmonella was accomplished, using data from records of horses hospitalized in the period July 1971 through June 1982. Horses in which nasogastric tubes were passed were at 2.9 times greater risk of having Salmonella isolated, compared with horses that did not undergo this procedure. Horses treated with antibiotics parenterally were at 6.4 times greater risk, and those treated with antibiotics orally and parenterally were at 40.4 times greater risk of developing salmonellosis, compared with horses not receiving such tre...
An outbreak of suspected equine infectious anaemia in Guyana. An outbreak of suspected equine infectious anaemia (EIA) among a population of 678 horses from 16 farms occurred in the Rupununi Savannahs of Guyana. Clinical signs of EIA were detected in 110 horses. Agar gel immunodiffusion (AGID) tests on 92 sera examined showed positive serological evidence of EIA in 67 (72·8%). The mean packed cell volume of 50 horses studied was 0·178
and the mean red blood cell count was 3·7 × 1012/l with the mean white blood cell count 4·1 × 109/l.
The morbidity rate of the disease was 14·0% and the mortality rate 11·1%. The majority (78%) of all seroposi...
Foetal and neonatal foal losses on equine herpesvirus type 1(EHV-1) infected farms before and after EHV-1 vaccination was introduced. On 6 farms with a history of EHV-1 abortions the overall prevalence of losses due to abortion, stillbirth and neonatal foal mortality during 5 foaling seasons preceding the introduction of vaccination against EHV-1 were compared with corresponding data for 8 subsequent seasons in which all horses were immunized with a modified live EHV-1 vaccine. Although both sporadic and epizootic EHV-1 abortions occurred in immunized mares, the numbers of foetal and neonatal foal losses decreased significantly (chi 2 = 15.75; p less than 0.001) from 11.8% (343 of 2897 pregnancies) during the seasons 1969-19...
[Endoscopic findings in horses with diseases of the upper respiratory tract]. With the aid of a flexible glassfibre endoscope, a 300 W cold light source and a special adapted camera, colour photographs of the upper respiratory tract of horses were taken. These pictures served to present especially the disease processes of the different areas of the upper respiratory tract which lead to a constriction of the lumen. These included proliferation in the nose, guttural pouch diseases and larynx diseases such as hemiplegia, subepiglottic cysts, epiglottic entrapment and rostral displacement of the plica palatopharyngica. Furthermore endoscopic findings of changes in the soft ...
Equine sarcoid: BCG immunotherapy compared to cryosurgery in a prospective randomised clinical trial. A total of 30 horses with single or multiple sarcoid tumors of the skin were randomly divided into three treatment groups: (i) cryosurgical treatment, (ii) intralesional immunotherapy with a live BCG vaccine, (iii) intralesional immunotherapy with a BCG cell wall preparation. Complete tumour regression was obtained in all 10 cryosurgically treated horses, in 6 of 10 live BCG treated horses, and in 7 of 10 BCG cell wall treated horses. One live BCG and 2 BCG cell wall treated horses showed partial tumour regression of more than 50% of the tumour area. Eleven horses with sarcoid tumours were not...
[The effect of vitamin H substitution on the growth and condition of hooves]. A long-term treatment with biotin (vitamin H) in 5 warm-blooded horses and 10 trotter horses is reported. The dose of 0.031-0.037 mg/kg body weight was well tolerated, and with a therapy period up to 10 months an improvement of the horn quality of the growing hoof could be attained as it had not been possible before with other measures. Biotin (Gabiotan) is recommendable as a therapeutic in all cases of hoof problems which are based on disturbed horn elasticity.
Segregation distortion within the equine MHC; analogy to a mouse T/t-complex trait. Segregation distortion was found for a haplotype of the equine lymphocyte antigen (ELA) system in an extended family of American Standardbred horses. In one sire family, consisting of a stallion and his 17 sons and grandsons, the gene for ELA-A10 (A10) was transmitted to 57.7% of 638 offspring scored (P = 0.001). Significant segregation distortion was not seen for mares or for unrelated stallions, regardless of the ELA markers they possessed. Since the effect was seen for this one sire family and not seen for other stallions with A10, it is unlikely that the gene for A10 is the cause of this p...
[Nomenclature of the clitoris and preputium of the mare in relation to the surgical removal of the clitoral sinus according to CEM regulations]. The cavity, that belongs to the glans clitoridis and that has to be removed in accord with the regulations and rules for the import of horses of CEM carrier states, has not been taken up in the NAV (1983). Conform to the statements of the clinical physicians and to the declarations of the American literature the nomenclature "Sinus clitoridis" is proposed for the international use.
Preparation of Clostridium septicum antigen for hyperimmunization of horses using a dialyzed culture. The preparation of toxic cultures of Clostridium septicum is described, using an apparatus with a straight dialysis tubing, where the medium is filled both into the nutrition and cultivation space of the apparatus. Using the cultivation to nutrition volume rate 1:2, mean titre of lethal antigen in filtrates 3.86 limes mortis per mL and 300 dosis lethalis minima per Lm was obtained in comparison with the values of 2.22 and 150 respectively in flask filtrates. Native filtrates of dialyzed cultures were better antigens for hyperimmunization of horses than the culture filtrates from flasks.
Renal toxicity of non-steroidal anti-inflammatory drugs. Non-steroidal anti-inflammatory drugs represent the most heavily prescribed and used class of drugs in human medicine. Most are derivatives of either salicylates, propionic acid, indoleacetic acid, anthranilic acid, pyrazolone, or oxicams. They depress the synthesis of prostaglandins from arachidonic acid by reversible inhibition of the enzyme cyclooxygenase. In the kidney, prostaglandins PGE2 and PGI2 modulate the vasoconstrictor effects of angiotensin II, norepinephrine, and vasopressin. In the presence of volume contraction, anesthesia, or disease states associated with high levels of these...
Paroxysmal atrial fibrillation in racehorses. The paper describes five cases of atrial fibrillation detected after racing. In four of them, the arrhythmia disappeared spontaneously within 24 h and they were regarded as paroxysmal in type. In the fifth case, which won its race, the arrhythmia persisted for at least 45 h after racing. It was therefore regarded as an example of persistent atrial fibrillation. It was then treated with quinidine sulphate which restored sinus rhythm. It would seem that paroxysmal atrial fibrillation may be a cause of sudden decrease in racing performance.
