The study of diseases in horses encompasses a wide range of conditions affecting equine health, including infectious diseases, metabolic disorders, and genetic abnormalities. These diseases can impact various systems within the horse, such as respiratory, gastrointestinal, and musculoskeletal systems, and can lead to significant health challenges. Research in this area focuses on understanding the pathophysiology, diagnosis, prevention, and treatment of equine diseases. Common diseases studied include equine influenza, equine herpesvirus, and laminitis. This page provides access to peer-reviewed research studies and scholarly articles that explore the etiology, clinical presentation, and management strategies of diseases in horses, contributing to the advancement of equine veterinary medicine.
Ushimi C, Henson JB, Gorham JR.Primary horse leukocyte cultures were inoculated with 2 or 10 50% tissue culture infective doses (TCID(50)) of equine infectious anemia (EIA) virus per cell, and the titer of cell-associated and fluid-phase virus was determined from 1 to 72 hr postinoculation (PI). Cover slips were collected from 4 to 72 hr PI and stained for EIA viral antigen by the indirect immunofluorescent (FA) technique. Viral replication was detected after a latent period of approximately 18 to 24 hr and reached peak titers of approximately 10(4.5) to 10(6) TCID(50)/0.5 ml from 48 to 72 hr PI. The fluid phase contained 1...
Little PB.A review of 6 cases of equine cerebrospinal nematodiasis diagnosed between 1958 and 1971 indicated that 2 major clinical syndromes occur—chronic incoordination and an acute progressive fatal encephalitic disease. The gross lesions of acute cases occur most commonly in the centrum ovale and the cerebellar roof nuclear region and appear as hemorrhagic serpentine tracks. The invariable existence of endocardial or proximal aortic verminous lesions caused by Strongylus vulgaris in horses with verminous encephalitis circumstantially incriminates S. vulgaris parasitic emboli as the most common caus...
Boulanger P, Bannister GL, Carrier SP.An agar-gel immunodiffusion test recommended for the diagnosis of equine infectious anemia was evaluated. Our preliminary observations confirmed those of Coggins concerning the mechanism of the test and the results obtained. Furthermore, emphasis was put on the difficulties encountered in the production of spleen antigens with an optimum amount of reactivity. Acetone-ether extraction procedures for the preparation of a liquid antigen extract are described. This type of antigen was reactive in the complement-fixation test in 1:8 or greater dilution and it is proposed to use the complement-fixat...
Nickels FA, Brown CM, Breeze RG.A unilateral pulmonary granular cell tumor occurred in a Thoroughbred mare with longstanding respiratory disease wrongly attributed to chronic obstructive pulmonary disease. The clinical features, radiology and endoscopic appearance permitted an accurate diagnosis, which was supported by subsequent necropsy and histologic examination. Obstructive pulmonary disease was ruled out after measurement of arterial blood gases and maximum intrathoracic pressure changes, and after microscopic examination of the lung.
Henker LC, Lorenzett MP, Piva MM, Wronski JG, de Andrade DGA, Borges AS, Driemeier D, Oliveira-Filho JP, Pavarini SP.Holoprosencephaly is a central nervous system malformation, characterized by incomplete or total lack of division of prosencephalon hemispheres, which is commonly accompanied by craniofacial malformations. A 9-month-gestation aborted American Quarter Horse fetus was submitted for postmortem examination. The fetus lacked haircoat and had severe facial malformations including marked shortening/absence of the maxillary, incisive and nasal bones, bilateral anophthalmia, and pre-maxillary agenesis. The prosencephalon was small and nearly spherical, represented by a single lobe, with no visible sepa...
Denyer MS, Crowther JR.Antigenic differences within equine-1 and equine-2 isolates of influenza were studied by haemagglutination inhibition tests, indirect ELISA and competition ELISA, using the same antisera. Better differentiation was obtained with the competition ELISA than with the other two tests. All three methods produced similar relationships within the equine-1 isolates but differed in their ability to differentiate the equine-2 isolates where the competition ELISA was superior and produced epidemiologically sensible results. In all three tests, post-infection ferret and horse sera were more useful in disc...
van Leeuwen W.A number of findings on twin pregnancies in mares recently reported in the literature are evaluated in the present paper. From these findings it emerges that twin pregnancies in mares very rarely develop from a synchronous (less than 2 days apart) double ovulation but rather from an asynchronous (much greater than 2 days apart) double ovulation. The significance of these findings in daily practice is pointed out. Moreover, it was found that in more than 50 per cent of the cases in which twin pregnancies had been diagnosed about day 20, one embryo had died by day 36. From this fact it is conclu...
Mullaney TP, Brown CM, Watson GL, Brandt LA.An apparently new and emerging fatal hepatic disease affecting foals is described. Characteristics included evidence of hepatic failure, marked biliary hyperplasia, hepatocellular necrosis and occasionally fibrosis. Generally, the features of the disease appear to differ markedly from other hepatic diseases of neonatal foals.
Van Hoogmoed L, Rakestraw PC, Snyder JR, Harmon FA.To determine the in vitro effect of various prostaglandins (PG) and nonsteroidal anti-inflammatory drugs (NSAID) on contractile activity of the large-colon taenia of horses. Methods: 14 healthy horses. Methods: The taenia was collected from the ventral colon, cut into strips (2 X 10 mm), and mounted in a tissue bath system (20-ml capacity) that contained oxygenated Krebs buffer solution warmed to 37.5+/-0.5 C. After equilibration, incremental doses of PGE2, PGF2alpha, PGl2, flunixin meglumine, carprofen, ketoprofen, and phenylbutazone were added to the baths, and contractile activity was recor...
