Hemoglobin is an iron-containing protein found in the red blood cells of horses, responsible for the transport of oxygen from the lungs to the tissues and the return of carbon dioxide from the tissues to the lungs. It plays a vital role in maintaining cellular respiration and energy metabolism. The structure and function of hemoglobin can be influenced by various factors, including genetics, age, and health status. Research into equine hemoglobin includes studies on its biochemical properties, the impact of different physiological and pathological conditions on its levels, and its importance in performance and endurance. This page compiles peer-reviewed research studies and scholarly articles that explore the characteristics, regulation, and clinical implications of hemoglobin in equine physiology and health.
Mehrazin H, Sakha M, Safi S.Due to their high specificity and exclusive cardiac myocyte sensitivity, cardiac troponins T and I (cTnT, cTnI) are currently regarded as ideal biomarkers to identify cardiomyocyte damage, myocardial injury, myocardial infarction, and chronic heart failure. In fact, cTnI is considered the most reliable biomarker for diagnosing heart-related issues. This study aimed to investigate the effects of age, gender, and exercise training on serum cTnI levels and various parameters related to the cardiovascular capacity of Caspian horses. For this purpose, 50 adult Caspian horses over 3 years old, both ...
Hisaeda K, Ono T, Shimokawa-Miyama T, Hata A, Iwata E, Hiasa Y, Ohzawa E, Tozaki T, Murase H, Takasu M, Nishii N, Kitagawa H.We examined the differences in serum iron (Fe) concentrations and related variables between summer and winter in Noma horses. Blood samples were collected from 37 clinically normal horses seven consecutive times: September 2018, February 2019, October 2019, February 2020, September 2020, February 2021, and February 2022. Serum Fe concentrations ranged from 74 μg/dl to 316 μg/dl with a median of 176 μg/dl. The concentrations were lower in stallions compared with mares and geldings, tended to be low at 10-14 years of age, and then increased with age. Serum Fe concentrations were repeatedly lo...
Muir WW, Yiew XT, Bateman SW, Hahn RG.Fluid therapy in horses is primarily empirical. Evidence-based quantification of the disposition of intravenous (IV) crystalloids used in clinical practice could enhance the effectiveness of fluid therapy. Objective: To determine the pharmacokinetics (i.e., volume kinetics: VK) and associated haemodynamic effects of IV lactated Ringer's solution (LRS) in adult euvolemic horses. Methods: Unmasked multiple subjects, single baseline design. Methods: Thirteen healthy, euvolemic adult female horses were administered an IV bolus of LRS and monitored over 4 h. Haemoglobin, albumin and haematocrit c...
Santos L, Werfel K, Ferlini-Agne G.Accurate measurement of haemoglobin concentration is crucial for monitoring the oxygen-carrying capacity in anaesthetised horses. This prospective study aimed to determine the agreement in haemoglobin concentration in anaesthetised horses using the SpHb pulse co-oximeter, an Epoc® blood gas analyser, and values derived from packed cell volume (PCV), which served as the reference method in this study. The study included 34 horses undergoing elective surgeries. Blood samples were collected from each horse and divided for analysis using the microhaematocrit method to estimate haemoglobin concent...
de Luna Paiva TD, de Melo Lopes AR, Silva ÁJC, Figueiredo MAF, da Cunha Nogueira SS, Nogueira-Filho SLG.Medical ozone is used in various treatments due to its oxidising properties. Objective: We aimed in this study to evaluate the impact of intrarectal ozone therapy on haematological and biochemical parameters, as well as the pain induced by the procedure in sport horses. Methods: In vivo experiment with 12 Quarter Horses (3 males and 9 females) used as their own controls to assess the effects of ozone therapy. Methods: Blood samples were collected before treatment (Control), 24 h after ozone therapy (24 h post-treatment), and 7 days after the last day of ozone therapy (7 days post-treatment). ...