Topic:Phenothiazine
Phenothiazine is a chemical compound that has been studied for its effects and potential applications in horses. It is primarily known for its use as an antipsychotic and antiemetic in human medicine, but its derivatives have been explored for various purposes in veterinary contexts. In equine medicine, phenothiazine derivatives have been investigated for their potential use as anthelmintics, which are agents that expel parasitic worms. The compound's mode of action involves interfering with the nervous system of parasites, leading to their expulsion from the host. This page compiles peer-reviewed research studies and scholarly articles that explore the pharmacological properties, efficacy, and safety of phenothiazine and its derivatives in horses, as well as their impact on equine health and management practices.
Piperazine resistance in population-B equine strongyles: a study of selection in Thoroughbreds in Kentucky from 1966 through 1983. Observations were completed over an 18-year period (1966 through 1983) in Thoroughbred mares (15/year) and yearlings (11 to 24/year) on a farm where benzimidazole-resistant small strongyles had emerged previously (1962 to 1965). This farm was operated as a closed, nonboarding type, which included a racing stable for its home-bred foals. At 2-week intervals, counts of worm eggs per gram of feces (EPG) and larvae per gram of feces were done to monitor strongyle infections and efficacies of bimonthly (every 8 weeks) antiparasitic treatments that were administered by stomach tube or were fed (dich...