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Topic:Reactivity

Reactivity in horses refers to the behavioral and physiological responses that horses exhibit in response to stimuli or changes in their environment. These responses can include heightened alertness, increased heart rate, and changes in movement patterns. Reactivity is influenced by various factors, including genetics, past experiences, and the current environment. Understanding a horse's reactivity is important for managing their behavior, training, and welfare. This page compiles peer-reviewed research studies and scholarly articles that explore the factors influencing reactivity in horses, methods for measuring and assessing these responses, and the implications for equine management and training practices.
Horse allergy: Curly Horses can mediate immune tolerance.
Pneumologie (Stuttgart, Germany)    October 12, 2023   Volume 78, Issue 1 47-57 doi: 10.1055/a-2101-9533
Mitlehner A, Mitlehner C, Reißmann M, Stoll P, Swoboda I, Mitlehner W.American Bashkir Curly Horses are claimed to be hypoallergenic, but this has not been clinically proven. In the present study, the effect of exposure to Curly Horses was investigated in 141 patients allergic to horses by measuring their lung function and nasal patency during Curly Horse contact. Continuous contact with Curly Horses, including riding and brushing, decreased the allergic riders' reactivity as measured by FEV1, PEF, and PNIF. Subsequent visits (up to 40 or more hours of riding) further reduced reactivity to the Curly Horses. Allergic events to horses occurred only in 72 out of 13...
The chemistry of snake venom and its medicinal potential.
Nature reviews. Chemistry    June 10, 2022   Volume 6, Issue 7 451-469 doi: 10.1038/s41570-022-00393-7
Oliveira AL, Viegas MF, da Silva SL, Soares AM, Ramos MJ, Fernandes PA.The fascination and fear of snakes dates back to time immemorial, with the first scientific treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt. Owing to their lethality, snakes have often been associated with images of perfidy, treachery and death. However, snakes did not always have such negative connotations. The curative capacity of venom has been known since antiquity, also making the snake a symbol of pharmacy and medicine. Today, there is renewed interest in pursuing snake-venom-based therapies. This Review focuses on the chemistry of snake venom an...
Progressive habituation to separation alleviates the negative effects of weaning in the mother and foal.
Psychoneuroendocrinology    July 5, 2018   Volume 97 59-68 doi: 10.1016/j.psyneuen.2018.07.005
Lansade L, Foury A, Reigner F, Vidament M, Guettier E, Bouvet G, Soulet D, Parias C, Ruet A, Mach N, Lévy F, Moisan MP.Early and definitive separation between offspring and their mothers has negative consequences on behavioral and physiological responses. This study compared sudden and definitive weaning (Sudd group, N = 16) and weaning involving progressive habituation to separation using a fence line during the month preceding definitive separation (Prog group, N = 18). The impact of these two methods was assessed in both foals and their mothers through behavioral and biological parameters, including salivary cortisol, telomere length and blood transcriptomes. On the day of definitive separation, Pro...
Behavioral and Transcriptomic Fingerprints of an Enriched Environment in Horses (Equus caballus).
PloS one    December 10, 2014   Volume 9, Issue 12 e114384 doi: 10.1371/journal.pone.0114384
Lansade L, Valenchon M, Foury A, Neveux C, Cole SW, Layé S, Cardinaud B, Lévy F, Moisan MP.The use of environmental enrichment (EE) has grown in popularity over decades, particularly because EE is known to promote cognitive functions and well-being. Nonetheless, little is known about how EE may affect personality and gene expression. To address this question in a domestic animal, 10-month-old horses were maintained in a controlled environment or EE for 12 weeks. The control horses (n = 9) lived in individual stalls on wood shaving bedding. They were turned out to individual paddocks three times a week and were fed three times a day with pellets or hay. EE-treated horses (n =â€...
Oxidation of methionine residues in equine growth hormone by Chloramine-T.
The International journal of biochemistry    August 1, 1993   Volume 25, Issue 8 1189-1193 doi: 10.1016/0020-711x(93)90598-9
Mihajlovic V, Cascone O, Biscoglio de Jiménez Bonino MJ.1. Reactivity of methionine residues towards Chloramine-T was studied in the equine growth hormone. 2. With a 20.0-fold molar excess of reagent over methionine, full oxidation of the four residues of the protein is achieved. 3. Methionine 4 is the most reactive group, followed by methionines 72 and 178--methionine 123 being the less reactive residue. 4. As judged by circular dichroism spectra and binding assays, protein conformation and binding capacity to specific receptors remains unchanged even after full oxidation of all four methionine residues. 5. Results agree with data previously obtai...