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Nature2000; 403(6768); 382-383; doi: 10.1038/35000284

A function for guttural pouches in the horse.

Abstract: Athletic animals must keep their brains cool during exertion because this organ can be damaged irreversibly by hyperthermia. But how horses do this has remained a mystery, as they don't appear to have thermoregulatory dervices like those found in other animals. They do, however, have a unique anatomical arrangement of their internal carotid arteries, which supply blood to the brain: these are enveloped by a pair of air-filled guttural pouches. Here we show that horses use their guttural pouches to cool these important arteries during exercise, keeping the brain from overheating.
Publication Date: 2000-02-10 PubMed ID: 10667779DOI: 10.1038/35000284Google Scholar: Lookup
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  • Journal Article

Summary

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This research uncovers the unique role of guttural pouches in horses in cooling their blood and, in turn, protecting their brains from overheating during exercise.

Objective of the Research

  • This study was conducted to shed light on how horses, as athletic animals, regulate their body temperature, particularly the heat of their brains, during strenuous activities. Prior to the research, this remained unclear as horses do not seemingly possess the usual thermoregulatory devices seen in other animal species.

Unique Anatomical Feature

  • The research highlighted the unique anatomical configuration of horses’ internal carotid arteries which supply blood to the brain. Unlike in other animals, these arteries in horses are enclosed by a pair of air-filled guttural pouches. This unique arrangement piqued the interest of researchers and they sought to find out whether these pouches contribute to the cooling mechanism of the horse’s body.

Key Findings

  • The study revealed that horses utilize their guttural pouches to cool their carotid arteries during physical exertion. The air-filled pouches appear to act as temperature-moderating systems, effectively cooling the blood circulating to the brain through the carotid arteries.
  • By reducing the temperature of the blood going through them, the guttural pouches help to guard the horse’s brain from overheating, a condition (hyperthermia) which can cause irreversible damage to the organ.

Implication of the Study

  • This finding is significant as it uncovers a unique thermoregulatory mechanism in horses which allows them to engage in strenuous physical activities without damaging their brains due to overheating. This knowledge can prove useful in managing the health and performance of athletic horses.

Cite This Article

APA
Baptiste KE, Naylor JM, Bailey J, Barber EM, Post K, Thornhill J. (2000). A function for guttural pouches in the horse. Nature, 403(6768), 382-383. https://doi.org/10.1038/35000284

Publication

ISSN: 0028-0836
NlmUniqueID: 0410462
Country: England
Language: English
Volume: 403
Issue: 6768
Pages: 382-383

Researcher Affiliations

Baptiste, K E
  • Department of Veterinary Internal Medicine, University of Saskatchewan, Saskatoon, Canada. keb@svs.dk
Naylor, J M
    Bailey, J
      Barber, E M
        Post, K
          Thornhill, J

            MeSH Terms

            • Animals
            • Body Temperature Regulation / physiology
            • Brain / physiology
            • Carotid Artery, Internal / anatomy & histology
            • Carotid Artery, Internal / physiology
            • Cavernous Sinus / physiology
            • Eustachian Tube / anatomy & histology
            • Eustachian Tube / physiology
            • Horses / anatomy & histology
            • Horses / physiology
            • Physical Exertion

            Citations

            This article has been cited 5 times.
            1. Kang H, Zsoldos RR, Sole-Guitart A, Narayan E, Cawdell-Smith AJ, Gaughan JB. Heat stress in horses: a literature review. Int J Biometeorol 2023 Jun;67(6):957-973.
              doi: 10.1007/s00484-023-02467-7pubmed: 37060454google scholar: lookup
            2. Bhattacharjee S, Ceri Davies D, Holland JC, Holmes JM, Kilroy D, McGonnell IM, Reynolds AL. On the importance of integrating comparative anatomy and One Health perspectives in anatomy education. J Anat 2022 Mar;240(3):429-446.
              doi: 10.1111/joa.13570pubmed: 34693516google scholar: lookup
            3. Koch DW, Easley JT, Nelson BB, Delcambre JJ, McCready EG, Hackett ES. Comparison of two techniques for transpharyngeal endoscopic auditory tube diverticulotomy in the horse. J Vet Sci 2018 Nov 30;19(6):835-839.
              doi: 10.4142/jvs.2018.19.6.835pubmed: 30173496google scholar: lookup
            4. Mitchell G, Fuller A, Maloney SK, Rump N, Mitchell D. Guttural pouches, brain temperature and exercise in horses. Biol Lett 2006 Sep 22;2(3):475-7.
              doi: 10.1098/rsbl.2006.0469pubmed: 17148434google scholar: lookup
            5. Lepage OM. Guttural Pouch Mycosis: A Three-Step Therapeutic Approach. Vet Sci 2024 Jan 19;11(1).
              doi: 10.3390/vetsci11010041pubmed: 38275923google scholar: lookup