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Journal of the American Veterinary Medical Association2022; 260(S3); S94-S101; doi: 10.2460/javma.22.06.0272

A starch-rich treat affects enteroinsular responses in ponies.

Abstract: To determine the effect of a starch-rich treat, added to the daily diet of ponies for 10 days, on enteroinsular responses to meal consumption. 10 mixed-breed adult ponies owned by Queensland University of Technology were used in the study. Six ponies were metabolically healthy, and 4 were insulin dysregulated at the start of the study, according to the results of an in-feed oral glucose test. A bread-based treat was offered twice daily for 10 days, adding 0.36 ± 0.04 g/kg body weight (BW) carbohydrates to the daily diet. Before and after treatment, the intestinal capacity for simple carbohydrate absorption was approximated with a modified D-xylose absorption test. Plasma glucagon-like peptide-2 (GLP-2), blood glucose, and serum insulin responses to eating were also measured before and after treatment. The absorption of D-xylose (area under the curve [AUC]) increased 1.6-fold (P < .001) after 10 days of eating the treat. In addition, while basal (fasted) GLP-2 concentrations were not affected, GLP-2 AUC increased 1.4-fold in response to eating (P = .005). The treat did not change blood glucose or serum insulin concentrations, before, during, or after eating. A small amount of additional carbohydrate each day in the form of a treat can cause a measurable change in the enteroinsular responses to eating.
Publication Date: 2022-10-06 PubMed ID: 36191143DOI: 10.2460/javma.22.06.0272Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research study investigates how a starch-rich treat added to the daily diets of ponies alters their enteroinsular responses to eating. The findings show that such a treat can indeed cause measurable changes to those responses.

Methods and Subjects

  • The researchers used 10 mixed-breed adult ponies owned by Queensland University of Technology.
  • Among these ponies, six were metabolically healthy and four were insulin dysregulated, as determined by an in-feed oral glucose test.

Treatment

  • The researchers offered a bread-based treat twice daily to the ponies for a duration of 10 days.
  • This added an extra 0.36 ± 0.04 g/kg body weight (BW) of carbohydrates to their daily diet.

Tests and Measures

  • Before and after the treatment, the team approximated the ponies’ intestinal capacity for simple carbohydrate absorption with a modified D-xylose absorption test.
  • They measured the plasma glucagon-like peptide-2 (GLP-2), blood glucose, and serum insulin responses to eating before and after treatment.

Findings

  • The absorption of D-xylose, gauged by the area under the curve (AUC), increased by 1.6-fold after the ponies ate the treat for 10 days.
  • Even though basal (fasted) GLP-2 concentrations were not affected, the GLP-2 AUC increased 1.4-fold in response to eating.
  • The blood glucose or serum insulin concentrations remained unchanged before, during, or after eating.

Conclusion

  • The research concluded that even a small additional intake of carbohydrates each day, in the form of a treat, can bring about a measurable change in the ponies’ enteroinsular responses to eating.

Cite This Article

APA
Sibthorpe PEM, Fitzgerald DM, Chen L, Sillence MN, de Laat MA. (2022). A starch-rich treat affects enteroinsular responses in ponies. J Am Vet Med Assoc, 260(S3), S94-S101. https://doi.org/10.2460/javma.22.06.0272

Publication

ISSN: 1943-569X
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 260
Issue: S3
Pages: S94-S101

Researcher Affiliations

Sibthorpe, Poppy E M
  • School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
Fitzgerald, Danielle M
  • School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
Chen, Lan
  • Central Analytical Research Facility, Queensland University of Technology, Brisbane, QLD, Australia.
Sillence, Martin N
  • School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
de Laat, Melody A
  • School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.

MeSH Terms

  • Horses
  • Animals
  • Blood Glucose
  • Starch
  • Xylose
  • Insulin
  • Diet

Citations

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