A starch-rich treat affects enteroinsular responses in ponies.
Abstract: To determine the effect of a starch-rich treat, added to the daily diet of ponies for 10 days, on enteroinsular responses to meal consumption. 10 mixed-breed adult ponies owned by Queensland University of Technology were used in the study. Six ponies were metabolically healthy, and 4 were insulin dysregulated at the start of the study, according to the results of an in-feed oral glucose test. A bread-based treat was offered twice daily for 10 days, adding 0.36 ± 0.04 g/kg body weight (BW) carbohydrates to the daily diet. Before and after treatment, the intestinal capacity for simple carbohydrate absorption was approximated with a modified D-xylose absorption test. Plasma glucagon-like peptide-2 (GLP-2), blood glucose, and serum insulin responses to eating were also measured before and after treatment. The absorption of D-xylose (area under the curve [AUC]) increased 1.6-fold (P < .001) after 10 days of eating the treat. In addition, while basal (fasted) GLP-2 concentrations were not affected, GLP-2 AUC increased 1.4-fold in response to eating (P = .005). The treat did not change blood glucose or serum insulin concentrations, before, during, or after eating. A small amount of additional carbohydrate each day in the form of a treat can cause a measurable change in the enteroinsular responses to eating.
Publication Date: 2022-10-06 PubMed ID: 36191143DOI: 10.2460/javma.22.06.0272Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The research study investigates how a starch-rich treat added to the daily diets of ponies alters their enteroinsular responses to eating. The findings show that such a treat can indeed cause measurable changes to those responses.
Methods and Subjects
- The researchers used 10 mixed-breed adult ponies owned by Queensland University of Technology.
- Among these ponies, six were metabolically healthy and four were insulin dysregulated, as determined by an in-feed oral glucose test.
Treatment
- The researchers offered a bread-based treat twice daily to the ponies for a duration of 10 days.
- This added an extra 0.36 ± 0.04 g/kg body weight (BW) of carbohydrates to their daily diet.
Tests and Measures
- Before and after the treatment, the team approximated the ponies’ intestinal capacity for simple carbohydrate absorption with a modified D-xylose absorption test.
- They measured the plasma glucagon-like peptide-2 (GLP-2), blood glucose, and serum insulin responses to eating before and after treatment.
Findings
- The absorption of D-xylose, gauged by the area under the curve (AUC), increased by 1.6-fold after the ponies ate the treat for 10 days.
- Even though basal (fasted) GLP-2 concentrations were not affected, the GLP-2 AUC increased 1.4-fold in response to eating.
- The blood glucose or serum insulin concentrations remained unchanged before, during, or after eating.
Conclusion
- The research concluded that even a small additional intake of carbohydrates each day, in the form of a treat, can bring about a measurable change in the ponies’ enteroinsular responses to eating.
Cite This Article
APA
Sibthorpe PEM, Fitzgerald DM, Chen L, Sillence MN, de Laat MA.
(2022).
A starch-rich treat affects enteroinsular responses in ponies.
J Am Vet Med Assoc, 260(S3), S94-S101.
https://doi.org/10.2460/javma.22.06.0272 Publication
Researcher Affiliations
- School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
- School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
- Central Analytical Research Facility, Queensland University of Technology, Brisbane, QLD, Australia.
- School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
- School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
MeSH Terms
- Horses
- Animals
- Blood Glucose
- Starch
- Xylose
- Insulin
- Diet
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