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Accuracy of open magnetic resonance imaging for guiding injection of the equine deep digital flexor tendon within the hoof.

Abstract: Lesions of the distal deep digital flexor tendon (DDFT) are frequently diagnosed using MRI in horses with foot pain. Intralesional injection of biologic therapeutics shows promise in tendon healing; however, accurate injection of distal deep digital flexor tendon lesions within the hoof is difficult. The aim of this experimental study was to evaluate accuracy of a technique for injection of the deep digital flexor tendon within the hoof using MRI-guidance, which could be performed in standing patients. We hypothesized that injection of the distal deep digital flexor tendon within the hoof could be accurately guided using open low-field MRI to target either the lateral or medial lobe at a specific location. Ten cadaver limbs were positioned in an open, low-field MRI unit. Each distal deep digital flexor tendon lobe was assigned to have a proximal (adjacent to the proximal aspect of the navicular bursa) or distal (adjacent to the navicular bone) injection. A titanium needle was inserted into each tendon lobe, guided by T1-weighted transverse images acquired simultaneously during injection. Colored dye was injected as a marker and postinjection MRI and gross sections were assessed. The success of injection as evaluated on gross section was 85% (70% proximal, 100% distal). The success of injection as evaluated by MRI was 65% (60% proximal, 70% distal). There was no significant difference between the success of injecting the medial versus lateral lobe. The major limitation of this study was the use of cadaver limbs with normal tendons. The authors conclude that injection of the distal deep digital flexor tendon within the hoof is possible using MRI guidance.
Publication Date: 2017-07-06 PubMed ID: 28681515DOI: 10.1111/vru.12523Google Scholar: Lookup
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  • Journal Article

Summary

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The study discusses the use of open magnetic resonance imaging (MRI) to accurately guide injections into the deep digital flexor tendon found within the hoof of horses. The paper suggests that the use of this method can potentially improve the effectiveness of treatments involving biologic therapeutics.

Introduction

  • The research primarily focuses on investigating the accuracy of using open low-field MRI to guide injections in the deep digital flexor tendon (DDFT) of horses that suffer from hoof pain due to lesions or injuries.
  • Horses often get lesions in their DDFT, and these lesions are usually diagnosed using MRI. In order to enhance the healing process, biologic therapeutics are often injected directly into the tendon. However, carrying out this procedure accurately is challenging.
  • Despite the challenges, it’s important because inaccurate or ineffective injections may not yield the desired therapeutic results and could potentially aggravate the condition.

Methodology

  • The researchers used ten cadaver limbs positioned in an open, low-field MRI unit to test their hypothesis.
  • They used a titanium needle for injections, guided by T1-weighted transverse images that were captured simultaneously during the process.
  • Each DDFT lobe was assigned to have a proximal (adjacent to the proximal aspect of the navicular bursa) or distal (next to the navicular bone) injection. They injected colored dye as a marker to trace the procedure’s accuracy.

Results and Conclusion

  • The result of the study showed an 85% success rate for injections as evaluated on gross section, with a 70% success rate for proximal injections and 100% for distal ones.
  • On evaluating the success of the injections through MRI, they found that the rate was 65% overall, with a 60% success rate for proximal injections and 70% for distal ones.
  • Importantly, there was no significant difference in the success rates of injecting the medial versus lateral lobe, indicating that both could be targeted effectively using this method.
  • However, the study’s main limitation was that the experiment was conducted only on cadaver limbs with normal tendons, which may not accurately represent the conditions in a live horse with DDFT lesions.
  • The authors concluded the research by affirming that using open low-field MRI to guide injections in the DDFT within the hoof of horses is a feasible method.

Cite This Article

APA
Groom LM, White NA, Adams MN, Barrett JG. (2017). Accuracy of open magnetic resonance imaging for guiding injection of the equine deep digital flexor tendon within the hoof. Vet Radiol Ultrasound, 58(6), 671-678. https://doi.org/10.1111/vru.12523

Publication

ISSN: 1740-8261
NlmUniqueID: 9209635
Country: England
Language: English
Volume: 58
Issue: 6
Pages: 671-678

Researcher Affiliations

Groom, Lauren M
  • Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, VA, 24060.
White, Nathaniel A
  • Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, VA, 24060.
Adams, M Norris
  • Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, VA, 24060.
Barrett, Jennifer G
  • Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, VA, 24060.

MeSH Terms

  • Animals
  • Cadaver
  • Female
  • Foot Diseases / prevention & control
  • Foot Diseases / veterinary
  • Hoof and Claw / diagnostic imaging
  • Horse Diseases / prevention & control
  • Horses
  • Injections / methods
  • Injections / veterinary
  • Magnetic Resonance Imaging / veterinary
  • Male
  • Prospective Studies
  • Sensitivity and Specificity
  • Tendons / diagnostic imaging

Citations

This article has been cited 2 times.
  1. Kuffler DP. Variables affecting the potential efficacy of PRP in providing chronic pain relief.. J Pain Res 2019;12:109-116.
    doi: 10.2147/JPR.S190065pubmed: 30613159google scholar: lookup
  2. Kuffler DP. Differing efficacies of autologous platelet-rich plasma treatment in reducing pain following rotator-cuff injury in a single patient.. J Pain Res 2018;11:2239-2245.
    doi: 10.2147/JPR.S169647pubmed: 30349350google scholar: lookup