An equine joint friction test model using a cartilage-on-cartilage arrangement.
Abstract: This study describes an equine joint friction test using a cartilage-on-cartilage arrangement and investigates the influence of age and load on the frictional response. Osteochondral plugs were extracted from equine shoulder joints (2-5 years, n=12; 10-14 years, n=15), and mounted in a pin-on-disc tribometer. The frictional response was then measured under constant conditions (2N; 20 degrees C; 5 mm/s), and with increasing load (2N, 5N, 10N). In all experiments, the friction coefficient of young cartilage was significantly (P<0.001) smaller than obtained from old cartilage, while the application of a greater load resulted in a significant (P<0.001) decrease in friction coefficient only in old cartilage. It was concluded that cartilage ageing was responsible for an increase in friction coefficient under these experimental conditions. Moreover, where young cartilage lubrication remained stable, cartilage ageing may have been responsible for lubrication regime change. The cartilage-on-cartilage model could be used to better understand lubrication regime disturbances in healthy and diseased equine joints, and to test the efficacy of various bio-lubricant treatments.
Copyright (c) 2008 Elsevier Ltd. All rights reserved.
Publication Date: 2009-01-13 PubMed ID: 19141370DOI: 10.1016/j.tvjl.2008.12.003Google Scholar: Lookup
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- Journal Article
Summary
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The research article presents a study on testing joint friction in horses using a cartilage-on-cartilage model. It further signifies the impact of age and load on the frictional response of the joint.
Methodology
- The researchers developed an equine joint friction test model using a cartilage-on-cartilage arrangement. Osteochondral plugs were extracted from the shoulder joints of horses aged between 2-5 years (n=12) and 10-14 years (n=15).
- The plugs were then mounted in a pin-on-disc tribometer, a machine used to measure the frictional response against constant and varying loads.
- The test was performed under constant conditions (2N load; at 20 degrees C; speed 5 mm/s).
- The frictional response was also measured with increasing load (2N, 5N, 10N).
Findings and Conclusion
- The tests showed that the friction coefficient of young cartilage was significantly less than that obtained from old cartilage, which denotes an increase in joint friction as cartilage ages.
- Moreover, the application of greater load resulted in a significant decrease in friction coefficient in older cartilage, suggesting a change in lubrication regime potentially attributable to cartilage ageing.
- However, in the case of younger cartilage, lubrication remained stable under increased loads, signalling its natural capacity to maintain lubrication efficiency.
- The overall conclusion of the study points out that cartilage ageing plays a pivotal role in increasing joint friction and altering the cartilage’s lubrication mechanism.
Implications of the Research
- This cartilage-on-cartilage model developed in the study can be leveraged to gain deeper insights into lubrication regime disturbances in both healthy and diseased equine joints.
- The model can additionally be used to test the effectiveness of various bio-lubricant treatments, thus aiding in the development of potential therapeutic interventions for equine joint diseases.
Cite This Article
APA
Noble P, Collin B, Lecomte-Beckers J, Magnée A, Denoix JM, Serteyn D.
(2009).
An equine joint friction test model using a cartilage-on-cartilage arrangement.
Vet J, 183(2), 148-152.
https://doi.org/10.1016/j.tvjl.2008.12.003 Publication
Researcher Affiliations
- Department of Veterinary Anatomy, Liège University Faculty of Veterinary Medicine, Boulevard de Colonster, 20, B43, B-4000 Liège, Belgium. pnoble@ulg.ac.be
MeSH Terms
- Age Factors
- Animals
- Cartilage, Articular / physiology
- Friction
- Horse Diseases / therapy
- Horses / physiology
- Joint Diseases / therapy
- Joint Diseases / veterinary
- Stress, Mechanical
- Synovial Fluid / physiology
- Weight-Bearing / physiology
Citations
This article has been cited 2 times.- Mederake M, Trappe D, Jacob C, Hofmann UK, Schüll D, Dalheimer P, Exner L, Walter C. Influence of hyaluronic acid on intra-articular friction - a biomechanical study in whole animal joints. BMC Musculoskelet Disord 2022 Oct 20;23(1):927.
- Schwarz ML, Schneider-Wald B, Krase A, Richter W, Reisig G, Kreinest M, Heute S, Pott PP, Brade J, Schütte A. [Tribological assessment of articular cartilage. A system for the analysis of the friction coefficient of cartilage, regenerates and tissue engineering constructs; initial results]. Orthopade 2012 Oct;41(10):827-36.
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