Analysis of risk factors for recurrent airway obstruction in North American horses: 1,444 cases (1990-1999).
Abstract: To identify risk factors for recurrent airway obstruction (RAO) among horses examined at veterinary teaching hospitals in North America. Methods: Retrospective case-control study. Methods: 1,444 horses with RAO and 1,444 control horses examined for other reasons. Methods: The Veterinary Medical Database was searched for records of horses in which RAO was diagnosed. A control group was identified by randomly selecting a horse with a diagnosis other than RAO that matched the institution and year of admission for each of the horses with RAO. Information obtained included hospital, admission year and month, age, sex, breed, and discharge status. The association between risk factors and diagnosis of RAO was estimated with logistic regression models. Results: The risk of RAO increased significantly with age, with horses > or = 7 years old being 6 to 7 times as likely to have RAO as were horses or = 4 years old, and Thoroughbreds and that RAO has a seasonal distribution.
Publication Date: 2003-12-11 PubMed ID: 14664454DOI: 10.2460/javma.2003.223.1645Google Scholar: Lookup
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- Journal Article
- Age Factors
- Case Reports
- Clinical Study
- Clinical Symptoms
- Diagnosis
- Disease Diagnosis
- Disease Etiology
- Epidemiology
- Equine Health
- Horse Breeds
- Horses
- Recurrent Airway Obstruction
- Respiratory Disease
- Respiratory Health
- Retrospective Study
- Risk Factors
- Seasonal Variation
- Thoroughbreds
- Veterinary Care
- Veterinary Medicine
- Veterinary Research
Summary
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The research article is about an analysis conducted to identify risk factors for recurring airway obstruction (RAO) among horses in North American veterinary teaching hospitals.
Research Methodology
- The researchers conducted a retrospective case-control study in which they examined 1,444 horses diagnosed with RAO and compared them to an equal number of control horses that were examined for reasons other than RAO.
- The Veterinary Medical Database was used to find records of these horses. The control group was made up of horses randomly picked after matching their institution and year of admission to those with RAO diagnosis.
- Data obtained about these horses included the hospital of admission, admission year and month, the horse’s age, sex, breed and the discharge status.
- The association between risk factors and diagnosis of RAO was estimated through logistic regression models.
Results from the Research
- The findings showed that the risk of RAO significantly increases with the age of the horse. Horses 7 years old or older were 6 to 7 times as likely to have RAO compared to horses aged 4 or younger.
- Thoroughbred horses were 3 times as likely to be diagnosed with RAO compared to ponies.
- RAO diagnosis was 1.6 and 1.5 times as likely to occur during winter and spring respectively as compared to during summer.
Conclusions from the Study
- Based on the analysis, the study infers that RAO is more likely to be diagnosed in female horses, horses aged 4 years or older, and thoroughbreds.
- Additionally, there seems to be a seasonal distribution to RAO occurrence, with greater likelihood in winter and spring than in summer.
Cite This Article
APA
Couëtil LL, Ward MP.
(2003).
Analysis of risk factors for recurrent airway obstruction in North American horses: 1,444 cases (1990-1999).
J Am Vet Med Assoc, 223(11), 1645-1650.
https://doi.org/10.2460/javma.2003.223.1645 Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
MeSH Terms
- Age Factors
- Airway Obstruction / epidemiology
- Airway Obstruction / etiology
- Airway Obstruction / veterinary
- Animals
- Breeding
- Case-Control Studies
- Confidence Intervals
- Female
- Horse Diseases / epidemiology
- Horse Diseases / etiology
- Horses
- Logistic Models
- Male
- Odds Ratio
- Records / veterinary
- Recurrence
- Retrospective Studies
- Risk Factors
- Seasons
- Sex Factors
- United States / epidemiology
Citations
This article has been cited 14 times.- Frippiat T, Art T, Tosi I. Airway Hyperresponsiveness, but Not Bronchoalveolar Inflammatory Cytokines Profiles, Is Modified at the Subclinical Onset of Severe Equine Asthma.. Animals (Basel) 2023 Aug 1;13(15).
- Woodrow JS, Sheats MK, Cooper B, Bayless R. Asthma: The Use of Animal Models and Their Translational Utility.. Cells 2023 Apr 5;12(7).
- Akula S, Riihimäki M, Waern I, Åbrink M, Raine A, Hellman L, Wernersson S. Quantitative Transcriptome Analysis of Purified Equine Mast Cells Identifies a Dominant Mucosal Mast Cell Population with Possible Inflammatory Functions in Airways of Asthmatic Horses.. Int J Mol Sci 2022 Nov 12;23(22).
- Intemann S, Reckels B, Schubert D, Wolf P, Kamphues J, Visscher C. The Hygienic Status of Different Forage Types for Horses-A Retrospective Study on Influencing Factors and Associations with Anamnestic Reports.. Vet Sci 2022 May 6;9(5).
- Basano I, Romolo A, Iamone G, Memoli G, Riccio B, Lavoie JP, Miniscalco B, Bullone M. Giant Multinucleated Cells Are Associated with Mastocytic Inflammatory Signature Equine Asthma.. Animals (Basel) 2022 Apr 20;12(9).
- Simões J, Batista M, Tilley P. The Immune Mechanisms of Severe Equine Asthma-Current Understanding and What Is Missing.. Animals (Basel) 2022 Mar 16;12(6).
- Mainguy-Seers S, Diaw M, Lavoie JP. Lung Function Variation during the Estrus Cycle of Mares Affected by Severe Asthma.. Animals (Basel) 2022 Feb 17;12(4).
- Borowska A, Wolska D, Niedzwiedz A, Borowicz H, Jaworski Z, Siemieniuch M, Szwaczkowski T. Some Genetic and Environmental Effects on Equine Asthma in Polish Konik Horses.. Animals (Basel) 2021 Aug 3;11(8).
- Couetil L, Cardwell JM, Leguillette R, Mazan M, Richard E, Bienzle D, Bullone M, Gerber V, Ivester K, Lavoie JP, Martin J, Moran G, Niedźwiedź A, Pusterla N, Swiderski C. Equine Asthma: Current Understanding and Future Directions.. Front Vet Sci 2020;7:450.
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- Couëtil LL, Cardwell JM, Gerber V, Lavoie JP, Léguillette R, Richard EA. Inflammatory Airway Disease of Horses--Revised Consensus Statement.. J Vet Intern Med 2016 Mar-Apr;30(2):503-15.
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