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The Veterinary clinics of North America. Equine practice1987; 3(1); 1-14; doi: 10.1016/s0749-0739(17)30688-0

Anthelmintics used in treatment of parasitic infections of horses.

Abstract: The common anthelmintics used to treat parasitic infections of horses are described. Dosage, anthelmintic spectrum, formulation and administration, mode of action, toxicity contraindications, and resistance of parasites to anthelmintics are included.
Publication Date: 1987-04-01 PubMed ID: 3555721DOI: 10.1016/s0749-0739(17)30688-0Google Scholar: Lookup
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Summary

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This research paper discusses the various types of anthelmintics (anti-parasitic drugs) used to treat parasitic infections in horses, covering their dosage, spectrum of action, formulation, administration methods, action mode, potential toxicity, contraindications, and the issue of parasite resistance to these drugs.

Anthelmintics in Horse Treatment

The study focuses on the use of anthelmintics, which are medicines used to treat parasitic worm infections. In the context of the research, the primary subjects are horses, and how to efficiently handle their parasitic infections.

  • The anthelmintics discussed span a broad range, each having a unique mode of action and spectrum of functionality.
  • Information about the appropriate dosages for each anthelmintic type is provided, enabling better prescription of these drugs for effective treatment.

Formulation and Administration

This section highlights how the anthelmintics are processed into an applicable form and how they are accordingly administered to the horses.

  • The various formulations allow for a broad spectrum of delivery including injections, oral dosages etc. The choice depends on the type of parasite, the severity of infection and the specific drug.
  • In terms of administration, it delves into whether the treatment is delivered orally, via injection, etc, to provide effective results without causing harm to the horse.

Action Mode, Toxicity, and Contraindications

The research dives into the nitty-gritty of how these anthelmintics work, their potential side effects and when they should not be used.

  • The mode of action refers to the biological mechanism through which the medicine operates within the horse’s body to eliminate the parasites.
  • Possible toxic effects of the drugs are also examined. This helps to evaluate the safety profile of each anthelmintic and its potential adverse effects on horse health.
  • Contraindications entail situations or conditions under which a particular anthelmintic should not be used, ensuring that the treatment is not only effective but also safe for the horse.

Parasite Resistance

The article concludes with a discussion on parasite resistance to anthelmintics, an increasing concern in the veterinary field.

  • Parasite resistance refers to the ability of parasites to survive or even thrive despite the administration of anthelmintics that were initially effective against them.
  • Parasite resistance trend, causes, and possible approaches to manage or prevent the concern are deeply discussed in a bid to ensure sustainable use of anthelmintics in the future.

Cite This Article

APA
DiPietro JA, Todd KS. (1987). Anthelmintics used in treatment of parasitic infections of horses. Vet Clin North Am Equine Pract, 3(1), 1-14. https://doi.org/10.1016/s0749-0739(17)30688-0

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 3
Issue: 1
Pages: 1-14

Researcher Affiliations

DiPietro, J A
    Todd, K S

      MeSH Terms

      • Animals
      • Anthelmintics / therapeutic use
      • Benzimidazoles / therapeutic use
      • Guanidines / therapeutic use
      • Horse Diseases / drug therapy
      • Horses
      • Ivermectin / therapeutic use
      • Levamisole / therapeutic use
      • Organophosphorus Compounds / therapeutic use
      • Parasitic Diseases / drug therapy
      • Parasitic Diseases, Animal
      • Phenothiazines / therapeutic use
      • Piperazines / therapeutic use
      • Pyrantel / therapeutic use
      • Strongyle Infections, Equine / drug therapy

      Citations

      This article has been cited 1 times.
      1. Martin RJ, Robertson AP. Control of nematode parasites with agents acting on neuro-musculature systems: lessons for neuropeptide ligand discovery.. Adv Exp Med Biol 2010;692:138-54.
        doi: 10.1007/978-1-4419-6902-6_7pubmed: 21189677google scholar: lookup