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Irish veterinary journal2010; 63(6); 373-379; doi: 10.1186/2046-0481-63-6-373

Antimicrobial resistance in commensal faecal Escherichia coli of hospitalised horses.

Abstract: The objective of this study was to examine the impact of hospitalisation and antimicrobial drug administration on the prevalence of resistance in commensal faecal E. coli of horses. Faecal samples were collected from ten hospitalised horses treated with antimicrobials, ten hospitalised horses not treated with antimicrobials and nine non-hospitalised horses over a consecutive five day period and susceptibility testing was performed on isolated E. coli. Results revealed that hospitalisation alone was associated with increased prevalence of antimicrobial resistance and multidrug resistance in commensal E. coli of horses. Due to the risk of transfer of resistance between commensal and pathogenic bacteria, veterinarians need to be aware of possible resistance in commensal bacteria when treating hospitalised horses.
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Publication Date: 2010-06-01 PubMed ID: 21851747PubMed Central: PMC3113860DOI: 10.1186/2046-0481-63-6-373Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates how hospitalisation and the use of antimicrobial drugs affect the prevalence of resistance in the commensal faecal E. coli in horses. It found that the resistance to antimicrobial drugs increased even with hospitalisation alone, underscoring the importance of considering potential resistance in commensal bacteria in treating hospitalised horses.

Research Methodology

  • The research was conducted over five days with samples collected from three groups of horses: those hospitalised and treated with antimicrobials, those hospitalised but not treated with antimicrobials, and those not hospitalised.
  • The primary focus was on studying the commensal faecal Escherichia Coli (E. coli), which is intestinal bacterium that usually is non-pathogenic but helps in digestion.
  • Antibiotic susceptibility testing was executed on the isolated E. coli samples. This helped determine the extent of resistance to the drugs.

Key Findings

  • The results showed that the very act of hospitalisation was associated with an increase in antimicrobial resistance and multidrug resistance in the horses’ commensal E. coli.
  • The research did not distinguish between the impact of hospitalisation and the impact of antimicrobial treatment because both were associated with increased resistance. This does not imply causation but is an important correlation found in the research.

Implications

  • This research is significant because of the risk of transfer of resistance between harmless (commensal) and disease-causing (pathogenic) bacteria.
  • Increased resistance to antimicrobials can make it more challenging to treat diseases caused by pathogenic bacteria, which acquire this resistance.
  • There is an implication for veterinarians who need to remain cognizant of possible resistance in commensal bacteria when treating hospitalised horses or prescribing antibiotics.
  • Further research is needed to identify the specific aspects of hospitalization that lead to increased antimicrobial resistance and to develop strategies to manage this risk.

Cite This Article

APA
Bryan J, Leonard N, Fanning S, Katz L, Duggan V. (2010). Antimicrobial resistance in commensal faecal Escherichia coli of hospitalised horses. Ir Vet J, 63(6), 373-379. https://doi.org/10.1186/2046-0481-63-6-373

Publication

Irish veterinary journal
ISSN: 2046-0481
NlmUniqueID: 0100762
Country: Ireland
Language: English
Volume: 63
Issue: 6
Pages: 373-379

Researcher Affiliations

Bryan, Jill
  • Veterinary Clinical Studies, UCD Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland. bryanjill@hotmail.com.
Leonard, Nola
    Fanning, Séamus
      Katz, Lisa
        Duggan, Vivienne

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          Citations

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