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The Veterinary clinics of North America. Equine practice2004; 19(3); 645-vi; doi: 10.1016/j.cveq.2003.08.009

Antimicrobial therapy for gastrointestinal diseases.

Abstract: Antibiotics will always be needed in horses for many types of infections, but the adverse consequences also must be considered. For the conditions described in this article, there is justification for antibiotic therapy. The intestinal problems that antibiotics can induce are among the risks from their administration to horses. Disruption of the endogenous bacterial population, colitis, and diarrhea are the most common complications from antibiotic therapy.
Publication Date: 2004-01-27 PubMed ID: 14740761DOI: 10.1016/j.cveq.2003.08.009Google Scholar: Lookup
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Summary

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The research article deals with the use of antibiotics in horses for treating gastrointestinal diseases, while discussing the potential side-effects and risks associated with such treatment including disruption of natural bacteria, colitis and diarrhea.

Antibiotic Use in Equine Treatment

  • The research article emphasizes on the fact that antibiotics remain an essential part of treatment for multiple types of infections found in horses. When dealing with gastrointestinal diseases in particular, antibiotics show substantial effectiveness.
  • However, it is not without its drawbacks. Antibiotics, while combating harmful bacteria causing the disease, can often disrupt the delicate balance of endogenous bacteria in the equine gastrointestinal tract.

Adverse Consequences of Antibiotic Therapy

  • The study discusses the potential negative impact of antibiotics when used in treatment. The consequences can range from mild to severe, depending on various factors like the kind of antibiotics used, duration of the treatment, and the general health status of the horse at the start of the therapy.
  • Some of the most common complications identified in the research include colitis, which is inflammation of the colon, and diarrhea. Both of these conditions can cause discomfort to the animal and can further complicate the disease management process.

Risks and Justification of Antibiotic Therapy

  • In concluding, the authors make it clear that despite these potential issues, the need for antibiotics cannot simply be overruled. The benefits of using antibiotics for treating intestinal problems outweigh the risks.
  • Therefore, the specialists are to carefully consider these risks when planning and executing a treatment plan. The justified use of antibiotics should focus minimizing these negative effects, while exploiting the potent effects they have over the infections.

Cite This Article

APA
Papich MG. (2004). Antimicrobial therapy for gastrointestinal diseases. Vet Clin North Am Equine Pract, 19(3), 645-vi. https://doi.org/10.1016/j.cveq.2003.08.009

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 19
Issue: 3
Pages: 645-vi

Researcher Affiliations

Papich, Mark G
  • Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA. mark_papich@ncsu.edu

MeSH Terms

  • Animals
  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections / chemically induced
  • Bacterial Infections / microbiology
  • Bacterial Infections / veterinary
  • Colic / chemically induced
  • Colic / microbiology
  • Colic / veterinary
  • Diarrhea / chemically induced
  • Diarrhea / microbiology
  • Diarrhea / veterinary
  • Drug Resistance, Bacterial
  • Gastrointestinal Diseases / chemically induced
  • Gastrointestinal Diseases / microbiology
  • Gastrointestinal Diseases / veterinary
  • Horse Diseases / chemically induced
  • Horse Diseases / microbiology
  • Horses
  • Intestinal Absorption
  • Intestines / microbiology
  • Kinetics

References

This article includes 72 references

Citations

This article has been cited 3 times.
  1. Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel) 2024 Jul 29;13(8).
    doi: 10.3390/antibiotics13080713pubmed: 39200013google scholar: lookup
  2. Arnold C, Pilla R, Chaffin K, Lidbury J, Steiner J, Suchodolski J. Alterations in the Fecal Microbiome and Metabolome of Horses with Antimicrobial-Associated Diarrhea Compared to Antibiotic-Treated and Non-Treated Healthy Case Controls. Animals (Basel) 2021 Jun 17;11(6).
    doi: 10.3390/ani11061807pubmed: 34204371google scholar: lookup
  3. Leon IM, Lawhon SD, Norman KN, Threadgill DS, Ohta N, Vinasco J, Scott HM. Serotype Diversity and Antimicrobial Resistance among Salmonella enterica Isolates from Patients at an Equine Referral Hospital. Appl Environ Microbiol 2018 Jul 1;84(13).
    doi: 10.1128/AEM.02829-17pubmed: 29678910google scholar: lookup