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Equine veterinary journal2006; 38(6); 526-531; doi: 10.2746/042516406x155975

Are feeding practices associated with duodenitis-proximal jejunitis?

Abstract: Feeding concentrate has been putatively associated with risk of development of duodenitis-proximal jejunitis (DPJ); however, this association has not been evaluated systematically in a controlled study. Objective: To determine whether there was evidence that feeding practices were associated with increased odds of developing DPJ employing a case control study. Objective: The amount of concentrate fed daily to horses is significantly greater among horses that develop DPJ than control horses with either lameness or other types of colic. Methods: Feeding practices of cases of DPJ diagnosed between 1997 and 2003 were compared with those of 2 populations of control horses (colic controls and lameness controls) admitted to the clinic from the same time period. Following multiple imputation of missing data, comparisons were made using polytomous logistic regression. Results: Horses with DPJ were fed significantly more concentrate and were significantly more likely to have grazed pasture than either control populations; DPJ horses were significantly more likely to be female than were lameness horses. Results were unchanged after adjusting for bodyweight of the horse. Conclusions: Feeding and grazing practices differ among horses with DPJ relative to horses with other forms of colic and lame horses. Conclusions: The observed magnitudes of association were not sufficiently strong to merit diagnostic/predictive application; however, these observations, if substantiated by other studies, might provide important aetiological clues.
Publication Date: 2006-11-28 PubMed ID: 17124842DOI: 10.2746/042516406x155975Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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This study investigates the relationship between feeding practices and the development of duodenitis-proximal jejunitis (DPJ) in horses. It found evidence to suggest that horses fed with a higher amount of concentrate and those allowed to graze pastures were more likely to develop DPJ.

Research Objectives

  • The primary objective of this research was to understand the relationship between feeding practices and the development of duodenitis-proximal jejunitis (DPJ) in horses. Particularly, they wanted to see if the amount of concentrate fed daily to horses and/or their grazing practices influenced the occurrence of DPJ.

Methods and Approach

  • To achieve the research objectives, a comparative study was performed between horses diagnosed with DPJ between 1997 and 2003 and two control groups of horses. These control groups included horses admitted to the clinic due to either colic (a common digestive disorder in horses) or lameness during the same period.
  • The missing data in their records were managed through multiple imputations, after which comparisons were made among the groups using polytomous logistic regression.

Findings

  • The results of the study revealed that horses with DPJ were fed significantly more concentrate and were more likely to have grazed pasture than either control groups. Furthermore, it was found that female horses were significantly more likely to suffer from DPJ than male horses suffering from lameness.
  • The observed correlations remained unchanged even after adjusting for the bodyweight of the horses, thus suggesting a direct relationship between feeding practices and the onset of DPJ independent of the size or weight of the horse.

Conclusions

  • The study confirmed differences in feeding and grazing practices between horses with DPJ and those belonging to the two control groups, suffering either from other forms of colic or lameness.
  • Despite the significant correlations observed, the researchers cautioned against using these relationships for diagnostic or predictive applications due to the correlations not being strong enough. They suggest that if the observations are confirmed by future studies, they could provide important clues towards understanding the root causes of DPJ.

Cite This Article

APA
Cohen ND, Toby E, Roussel AJ, Murphey EL, Wang N. (2006). Are feeding practices associated with duodenitis-proximal jejunitis? Equine Vet J, 38(6), 526-531. https://doi.org/10.2746/042516406x155975

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 38
Issue: 6
Pages: 526-531

Researcher Affiliations

Cohen, N D
  • Department of Large Animal Clinical Sciences, College of Veterinary Medicine, College Station, Texas 77843-4475, USA.
Toby, E
    Roussel, A J
      Murphey, E L
        Wang, N

          MeSH Terms

          • Animal Feed / adverse effects
          • Animal Husbandry / methods
          • Animal Nutritional Physiological Phenomena / physiology
          • Animals
          • Case-Control Studies
          • Colic / epidemiology
          • Colic / etiology
          • Colic / veterinary
          • Duodenitis / epidemiology
          • Duodenitis / etiology
          • Duodenitis / veterinary
          • Female
          • Horse Diseases / epidemiology
          • Horse Diseases / etiology
          • Horses
          • Jejunal Diseases / epidemiology
          • Jejunal Diseases / etiology
          • Jejunal Diseases / veterinary
          • Lameness, Animal / epidemiology
          • Lameness, Animal / etiology
          • Logistic Models
          • Male
          • Retrospective Studies
          • Risk Factors
          • Sex Factors

          Grant Funding

          • R01 CA074552 / NCI NIH HHS
          • R01 CA074552-10A1 / NCI NIH HHS

          Citations

          This article has been cited 3 times.
          1. Curtis L, Burford JH, England GCW, Freeman SL. Risk factors for acute abdominal pain (colic) in the adult horse: A scoping review of risk factors, and a systematic review of the effect of management-related changes. PLoS One 2019;14(7):e0219307.
            doi: 10.1371/journal.pone.0219307pubmed: 31295284google scholar: lookup
          2. Arroyo LG, Gomez DE, Martins C. Equine duodenitis-proximal jejunitis: A review. Can Vet J 2018 May;59(5):510-517.
            pubmed: 29904204
          3. Pihl TH, Scheepers E, Sanz M, Goddard A, Page P, Toft N, Andersen PH, Jacobsen S. Influence of disease process and duration on acute phase proteins in serum and peritoneal fluid of horses with colic. J Vet Intern Med 2015 Mar-Apr;29(2):651-8.
            doi: 10.1111/jvim.12542pubmed: 25644457google scholar: lookup