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EFSA journal. European Food Safety Authority2022; 20(5); e07312; doi: 10.2903/j.efsa.2022.7312

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistant Staphylococcus aureus in cattle and horses.

Abstract: () was identified among the most relevant antimicrobial-resistant (AMR) bacteria in the EU for cattle and horses in previous scientific opinions. Thus, it has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on its eligibility to be listed, Annex IV for its categorisation according to disease prevention and control rules as in Article 9, and Article 8 for listing animal species related to the bacterium. The assessment has been performed following a methodology previously published. The outcome is the median of the probability ranges provided by the experts, which indicates whether each criterion is fulfilled (lower bound ≥ 66%) or not (upper bound ≤ 33%), or whether there is uncertainty about fulfilment. Reasoning points are reported for criteria with uncertain outcome. According to the assessment here performed, it is uncertain whether AMR can be considered eligible to be listed for Union intervention according to Article 5 of the AHL (60-90% probability). According to the criteria in Annex IV, for the purpose of categorisation related to the level of prevention and control as in Article 9 of the AHL, the AHAW Panel concluded that the bacterium does not meet the criteria in Sections 1, 2 and 4 (Categories A, B and D; 1-5%, 5-10% and 10-33% probability of meeting the criteria, respectively) and the AHAW Panel was uncertain whether it meets the criteria in Sections 3 and 5 (Categories C and E, 33-90% and 60-90% probability of meeting the criteria, respectively). The animal species to be listed for AMR according to Article 8 criteria include mainly mammals, birds, reptiles and fish.
Publication Date: 2022-05-10 PubMed ID: 35582361PubMed Central: PMC9087474DOI: 10.2903/j.efsa.2022.7312Google Scholar: Lookup
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  • Journal Article

Summary

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The research focused on assessing antimicrobial-resistant Staphylococcus aureus (AMR SA) in cattle and horses, using criteria laid out in the Animal Health Law (Regulation (EU) No 2016/429). The study was inconclusive on whether AMR SA should be listed for Union intervention. Specific sections of criteria were not met, while others remain uncertain.

Assessment Method

  • The research aimed to categorise antimicrobial-resistant Staphylococcus aureus (AMR SA) through the framework provided by the EU’s Animal Health Law (AHL).
  • Evaluation was based on various criteria established within AHL, with specific attention to disease profile and impacts, eligibility for listing, categorisation linked to disease prevention and control rules, and finally species associated with the bacterium.
  • The process of assessment follows a previously published methodology.

Outcomes and Conclusions

  • The results are expressed as the median of the probability ranges provided by the experts. These probabilities show whether each criterion is fulfilled (lower bound ≥ 66%), not met (upper bound ≤ 33%), or whether there’s uncertainty about fulfilment.
  • The study concluded it’s uncertain whether AMR SA can be considered eligible to be listed for Union intervention according to Article 5 of the AHL (60-90% probability).
  • With regards to categorisation linked to the level of prevention and control as in Article 9 of the AHL, the research found that the bacterium does not meet the criteria in Sections 1, 2 and 4, but there’s uncertainty whether it meets the criteria in Sections 3 and 5.
  • The types of animal species listed mainly include mammals, birds, reptiles, and fish in relation to AMR SA according to the criteria in Article 8.

Implication of Findings

  • The findings suggest that there is a need for more research and data to accurately categorise AMR SA as per the AHL.
  • The uncertainty surrounding the fulfilment of some criteria highlights the complexity of antimicrobial-resistant diseases in animals.
  • The study’s findings will serve as a vital reference point for future researchers aiming to contribute to the fastidious arena of antimicrobial resistance.

Cite This Article

APA
Nielsen SS, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortázar C, Herskin M, Michel V, Miranda Chueca MÁ, Padalino B, Pasquali P, Roberts HC, Spoolder H, Ståhl K, Velarde A, Viltrop A, Winckler C, Baldinelli F, Broglia A, Kohnle L, Alvarez J. (2022). Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistant Staphylococcus aureus in cattle and horses. EFSA J, 20(5), e07312. https://doi.org/10.2903/j.efsa.2022.7312

Publication

ISSN: 1831-4732
NlmUniqueID: 101642076
Country: United States
Language: English
Volume: 20
Issue: 5
Pages: e07312
PII: e07312

Researcher Affiliations

Nielsen, Søren Saxmose
    Bicout, Dominique Joseph
      Calistri, Paolo
        Canali, Elisabetta
          Drewe, Julian Ashley
            Garin-Bastuji, Bruno
              Gonzales Rojas, José Luis
                Gortázar, Christian
                  Herskin, Mette
                    Michel, Virginie
                      Miranda Chueca, Miguel Ángel
                        Padalino, Barbara
                          Pasquali, Paolo
                            Roberts, Helen Clare
                              Spoolder, Hans
                                Ståhl, Karl
                                  Velarde, Antonio
                                    Viltrop, Arvo
                                      Winckler, Christoph
                                        Baldinelli, Francesca
                                          Broglia, Alessandro
                                            Kohnle, Lisa
                                              Alvarez, Julio

                                                References

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