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Bilateral diaphragmatic paralysis in a pony.

Abstract: An adult pony had a 1-month history of severe respiratory distress that was resistant to treatment and environmental changes. Results of blood gas analysis were indicative of alveolar hypoventilation. Simultaneous recordings of thoracic and abdominal wall motion by inductance plethysmography, together with complete pulmonary mechanics evaluation that included transdiaphragmatic pressure monitoring, revealed complete passive behavior of the diaphragm during breathing. Because radiography, necropsy, and histologic examination did not reveal any major lesion to explain the clinical and functional observations, bilateral diaphragmatic paralysis was diagnosed.
Publication Date: 1994-08-15 PubMed ID: 7961096
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Summary

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The research article discusses a case of an adult pony diagnosed with Bilateral Diaphragmatic Paralysis, a condition that involved severe respiratory distress which was resistant to standard treatment practices, and not related to any detectable physical lesions.

Background

  • The case involved an adult pony which had been in severe respiratory distress for a month, and its condition did not improve with routine treatment and changes to its environment.
  • The study was necessitated by the rarity and complexity of equine respiratory disorders, and the need to determine the cause and possible treatment for this respiratory ailiness.

Methodology

  • The pony’s health was evaluated through various methods to derive a comprehensive understanding of its condition.
  • Blood gas analysis was performed to assess the pony’s pulmonary function, the results of which indicated alveolar hypoventilation, a condition characterized by inadequate ventilation leading to increased levels of carbon dioxide in the blood.
  • To scrutinize the intricacies of the pony’s respiratory pattern, simultaneous recordings of thoracic and abdominal wall motion were conducted using inductance plethysmography, a method that allows non-invasive tracking of lung volume changes.
  • Complete pulmonary mechanics evaluation, including monitoring of transdiaphragmatic pressure, was also performed to assess the functionality of the pony’s diaphragm during respiration.

Results

  • The tests revealed that the pony’s diaphragm showed completely passive behavior during breathing, implying that the muscular partition was not actively participating in the respiration process, causing abnormal breathing patterns and resulting in respiratory distress.
  • Radiography, necropsy, and histologic examination were also performed which came back negative, meaning there were no significant lesions or structural abnormalities identified that could explain the abnormal respiratory patterns the pony was experiencing.

Conclusion

  • On the basis of clinical and functional observations, a diagnosis of bilateral diaphragmatic paralysis was made. This is a medical condition where both sides of the diaphragm cease to function, leading to difficulty in breathing and in severe cases, respiratory failure.

Cite This Article

APA
Amory H, Lomba F, Lekeux PM, Solal AN, Jauniaux TP, Desmecht DJ. (1994). Bilateral diaphragmatic paralysis in a pony. J Am Vet Med Assoc, 205(4), 587-591.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 205
Issue: 4
Pages: 587-591

Researcher Affiliations

Amory, H
  • Department of Large Animal Medicine, Faculty of Veterinary Medicine, University of Liège, Belgium.
Lomba, F
    Lekeux, P M
      Solal, A N
        Jauniaux, T P
          Desmecht, D J

            MeSH Terms

            • Animals
            • Female
            • Horse Diseases / diagnosis
            • Horse Diseases / physiopathology
            • Horses
            • Plethysmography / veterinary
            • Pressure
            • Respiratory Function Tests / veterinary
            • Respiratory Paralysis / diagnosis
            • Respiratory Paralysis / physiopathology
            • Respiratory Paralysis / veterinary

            Citations

            This article has been cited 4 times.
            1. Byers S, Barrington G, Nelson D, Haldorson G, Holt T, Callan R. Neurological causes of diaphragmatic paralysis in 11 alpacas (Vicugna pacos). J Vet Intern Med 2011 Mar-Apr;25(2):380-5.
            2. Talavera-López J, Tur-Martín A. M-Mode and Tissue Doppler Ultrasonographic Assessment of Diaphragmatic Function in Dogs With and Without Respiratory Distress. Animals (Basel) 2025 Nov 21;15(23).
              doi: 10.3390/ani15233371pubmed: 41375430google scholar: lookup
            3. Saisawart P, Sutthigran S, Kasemsuwan T, Sakulsirajit R, Ritthikulprasert S, Tachampa K, Thanaboonnipat C, Choisunirachon N. Efficacy of ultrasonographic diaphragmatic parameters in distinguishing diaphragmatic dysfunction in cats. J Feline Med Surg 2024 Oct;26(10):1098612X241275290.
              doi: 10.1177/1098612X241275290pubmed: 39451117google scholar: lookup
            4. Saisawart P, Sutthigran S, Suksangvoravong H, Thanaboonnipat C, Ritthikulprasert S, Tachampa K, Choisunirachon N. Computed tomographic diaphragmatic thickness: a promising method for the evaluation of diaphragmatic muscle in cardiopulmonary diseased cats. Front Vet Sci 2023;10:1247531.
              doi: 10.3389/fvets.2023.1247531pubmed: 38164391google scholar: lookup