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Blister beetle poisoning in horses.

Abstract: Case records of 21 horses with acute illness following ingestion of hay containing dead striped blister beetles (Epicauta spp) were selected for review. Abdominal pain, fever, depression, frequent urination, shock, and, occasionally, synchronous diaphragmatic flutter characterized clinical illness. Hematologic findings included hemoconcentration, neutrophilic leukocytosis, and hypocalcemia. Hematuria and low urine specific gravity were abnormal urinalysis results. Sloughing of the epithelium of the esophageal part of the stomach, hemorrhagic and ulcerative cystitis, enterocolitis, and myocardial necrosis were important post-mortem findings. Signs and lesions in 5 horses experimentally poisoned were similar to those of the natural disease. The findings were regarded as sufficiently characteristic of blister beetle poisoning to be useful in differential diagnosis but were not constant in all cases. Therefore, when blister beetle poisoning is suspected, access of affected horses to hay containing striped blister beetles should be demonstrated.
Publication Date: 1978-07-01 PubMed ID: 670055
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  • Journal Article

Summary

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The research investigates the case of 21 horses that fell acutely ill after eating hay contaminated with dead striped blister beetles. The symptoms and postmortem findings were suggestive of blister beetle poisoning but were not consistent across all cases. The researchers concluded that detection of these beetles in the hay could confirm suspicion of this condition.

Understanding the Illness

The research presents a detailed review of symptoms which were triggered in horses when they consumed hay infested with dead blister beetles, a type of insect that carries a toxic substance called cantharidin. The symptoms displayed by the horses included:

  • Abdominal pain and fever, which are possibly a reaction to the swallow of toxin
  • Depression, a common behavior change seen in animals dealing with sickness or pain
  • Frequent urination and shock, which could denote damage to the urinary system
  • Synchronous diaphragmatic flutter, a rare muscle disorder that could cause difficulty in breathing

There were also some abnormal blood and urine test results recorded among these horses including hemoconcentration (an increase in the proportion of cells in the blood), neutrophilic leukocytosis (an increase in white blood cells), and hypocalcemia (low calcium in the blood).

Post-Mortem Findings

Through post-mortem examinations, the researchers drew attention to some critical interior damages in the horses:

  • Sloughing of the epithelium of the stomach’s esophageal part, suggesting severe internal injuries caused by the toxin.
  • Hemorrhagic and ulcerative cystitis, enterocolitis, which imply severe damage to the bladder, intestines, and colon respectively.
  • Myocardial necrosis, indicating serious damage to the heart muscles.

These deaths and symptoms also occurred in 5 horses that were purposefully exposed to the blister beetles, indicating a similar cause of the natural disease.

Summary of Findings

The research concluded that even though the symptoms and lesions can point towards blister beetle poisoning, they may not be present in every case. Therefore, researchers emphasized the importance of confirming the presence of blister beetles in the consumed hay when such poisoning is suspected. This research shines light on an under-studied field, providing valuable information for equine health practitioners.

Cite This Article

APA
Schoeb TR, Panciera RJ. (1978). Blister beetle poisoning in horses. J Am Vet Med Assoc, 173(1), 75-77.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 173
Issue: 1
Pages: 75-77

Researcher Affiliations

Schoeb, T R
    Panciera, R J

      MeSH Terms

      • Animals
      • Coleoptera
      • Horse Diseases / diagnosis
      • Horse Diseases / etiology
      • Horse Diseases / pathology
      • Horses
      • Intestines / pathology
      • Poisoning / diagnosis
      • Poisoning / pathology
      • Poisoning / veterinary

      Citations

      This article has been cited 2 times.
      1. Jakovac-Strajn B, Brozić D, Tavčar-Kalcher G, Babič J, Trilar T, Vengust M. Entomological Surveillance and Cantharidin Concentrations in Mylabris variabilis and Epicauta rufidorsum Blister Beetles in Slovenia. Animals (Basel) 2021 Jan 18;11(1).
        doi: 10.3390/ani11010220pubmed: 33477415google scholar: lookup
      2. Simpson KM, Streeter RN, De Souza P, Genova SG, Morgan SE. Cantharidin toxicosis in 2 alpacas. Can Vet J 2013 May;54(5):456-62.
        pubmed: 24155427