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Veterinary ophthalmology2015; 18(6); 462-471; doi: 10.1111/vop.12252

Central corneal thickness measurements and ultrasonographic study of the growing equine eye.

Abstract: The aim of this study was to determine the central corneal thickness (CCT) of healthy equine eyes with high-frequency ultrasound (HF) and ultrasound biomicroscopy (UBM) and to measure the axial dimensions with B-mode ultrasound. Additionally, the influence of the age on the measured dimensions of the globe was analyzed. Methods: Fifty warm blood horses (mean age 23.0 ± 21.12 months) were divided into 3 age groups (group 1: 0-6 months; group 2: ≥7-30 months; and group 3: ≥31-78 months). Methods: Corneal measurements were performed with a 22-MHz and a 50-MHz transducer. Crystalline lens thickness (CLT), vitreous chamber depth (VCD), and axial globe length (AGL) were measured at a frequency of 10 MHz. Anterior chamber depth (ACD) was calculated. The eyes were measured under general anesthesia nonrelated to this study. Results: The mean CCT of 50 eyes was 818 ± 41 μm. The mean values ± SD in mm for axial dimensions were AGL 34.7 ± 2.7, ACD 3.4 ± 0.7, CLT 10.0 ± 0.9, and VCD of 20.4 ± 1.5. A positive correlation with increasing age was found for all dimensions. No significant differences were found between the gender and the left or right eye. Conclusions: HF and UBM are valuable high-resolution imaging tools for CCT measurements in horses. The here-obtained values support previous findings that a positive correlation with increasing age exists for CCT, ACD, CLT, VCD, and AGL in horse.
Publication Date: 2015-01-27 PubMed ID: 25623263DOI: 10.1111/vop.12252Google Scholar: Lookup
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  • Journal Article

Summary

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This research aimed at determining the central corneal thickness (CCT) of healthy equine eyes through utlising high-frequency ultrasound and ultrasound biomicroscopy, coupled with measuring the axial dimensions with B-mode ultrasound. The influence of age on the globe’s measured dimensions was also analysed, concluding that high-frequency and ultrasound biomicroscopy are beneficial tools for CCT measurements in horses.

Research Methodology

  • The study utilised 50 warm-blooded horses with a mean age of 23.0 ± 21.12 months. These subjects were divided into three different age groups for the sake of better analysis.
  • The three age groups were 0-6 months, 7-30 months and 31-78 months respectively.
  • Two different types of transducers (22-MHz and 50-MHz) were used to carry out corneal measurements.
  • The team also measured the Crystalline lens thickness (CLT), vitreous chamber depth (VCD), and axial globe length (AGL) at a frequency of 10 MHz. The depth of the Anterior chamber (ACD) was calculated as a part of the study.
  • All eyes were measured under general anesthesia which was unrelated to this study.

Research Findings

  • The study found that the mean CCT for the 50 horse eyes measured was 818 ± 41 μm.
  • The computed mean values ± SD in millimeters for axial dimensions were AGL 34.7 ± 2.7, ACD 3.4 ± 0.7, CLT 10.0 ± 0.9, and a VCD of 20.4 ± 1.5.
  • The researchers found a positive correlation between increasing age in horses and the measured dimensions.
  • No significant differences were found between the eyes’ dimensions concerning the horses’ gender or whether it was the left or right eye.

Conclusion

  • The study concludes that the high-frequency and ultrasound biomicroscopy used in research are notable high-resolution imaging tools that help record accurate CCT measurements in horses.
  • The computed values from this study lend support to previous research findings that show a positive correlation between Rising age and CCT, ACD, CLT, VCD, and AGL in horses.

Cite This Article

APA
Herbig LE, Eule JC. (2015). Central corneal thickness measurements and ultrasonographic study of the growing equine eye. Vet Ophthalmol, 18(6), 462-471. https://doi.org/10.1111/vop.12252

Publication

ISSN: 1463-5224
NlmUniqueID: 100887377
Country: England
Language: English
Volume: 18
Issue: 6
Pages: 462-471

Researcher Affiliations

Herbig, Lena E
  • Small Animal Clinic, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany.
Eule, J Corinna
  • Small Animal Clinic, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany.

MeSH Terms

  • Animals
  • Cornea / anatomy & histology
  • Cornea / diagnostic imaging
  • Cornea / growth & development
  • Eye / anatomy & histology
  • Eye / diagnostic imaging
  • Eye / growth & development
  • Female
  • Horses / anatomy & histology
  • Horses / growth & development
  • Male
  • Ultrasonography