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Home / Equine Research Bank / Animals (Basel) / Chromosome Instability in Pony of Esperia Breed Naturally In...
Animals : an open access journal from MDPI2022; 12(20); 2817; doi: 10.3390/ani12202817

Chromosome Instability in Pony of Esperia Breed Naturally Infected by Intestinal Strongylidae.

Abstract: The Pony of Esperia is an Italian autochthonous horse breed reared in the wild on the Aurunci and Ausoni Mountains. Currently, it is considered an endangered breed, as its population consists of 1623 animals. It is therefore essential to identify all aspects that can improve the management and economy of its breeding, favoring its diffusion. In this paper, the effects of intestinal strongyle infection on the chromosome stability of peripheral blood lymphocytes (PBLs) was evaluated through aneuploidy and chromosome aberration (gap, chromatid and chromosome breaks, and the number of abnormal cells) test. Statistical difference in the mean values of aneuploidy, cells with chromosome abnormalities, and chromosome and chromatid breaks were observed between ponies with high fecal egg counts (eggs per gram > 930) and those with undetectable intestinal strongylosis. The causes of this phenomenon and possible repercussions on the management of Pony of Esperia are discussed in the paper.
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Publication Date: 2022-10-18 PubMed ID: 36290203PubMed Central: PMC9597782DOI: 10.3390/ani12202817Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article explores the effects of intestinal strongyle infection on the chromosomal stability of Italian Esperia ponies, focusing on aneuploidy and chromosome aberration. Significant differences were found in the mean values of aneuploidy, cells with chromosome abnormalities, and chromosome and chromatid breaks between ponies with high and undetectable levels of infection.

Introduction

  • The study is focused on the Pony of Esperia, a horse breed native to Italy which is currently endangered with a population of only 1623 animals.
  • The research aims to uncover potential factors that could aid in the management, preservation, and propagation of this breed.
  • The paper particularly examines the impact of intestinal strongyle infections on the chromosomal stability of these ponies’ peripheral blood lymphocytes (PBLs).

Methodology

  • The study employs an aneuploidy and chromosome aberration test to gauge the effects of the strongyle infection.
  • Observations were made for any chromosomal anomalies such as gaps, chromosome and chromatid breaks, and overall abnormal cell count.

Results

  • The research found statistically significant differences in the average values of aneuploidy, cells with chromosomal abnormalities, as well as chromosome and chromatid breaks.
  • These differences were observed between ponies with high fecal egg counts (with over 930 eggs per gram indicating a higher level of infection) and those with undetectable intestinal strongylosis.

Implications

  • The paper discusses the causes of this occurrence and the potential effects it could have on the management of the Pony of Esperia breed.
  • The findings can contribute to the understanding of the health and reproduction of these animals, which could subsequently inform preventive and treatment strategies against infections.
  • By improving the health outcomes of these ponies through better management, these insights may accelerate efforts towards conserving and increasing the population of this endangered breed.

Cite This Article

APA
D'Anza E, Buono F, Albarella S, Castaldo E, Pugliano M, Iannuzzi A, Cascone I, Battista E, Peretti V, Ciotola F. (2022). Chromosome Instability in Pony of Esperia Breed Naturally Infected by Intestinal Strongylidae. Animals (Basel), 12(20), 2817. https://doi.org/10.3390/ani12202817

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 12
Issue: 20
PII: 2817

Researcher Affiliations

D'Anza, Emanuele
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Buono, Francesco
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Albarella, Sara
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Castaldo, Elisa
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Pugliano, Mariagiulia
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Iannuzzi, Alessandra
  • National Research Council (CNR), Institute of Animal Production System in Mediterranean Environment (ISPAAM), Piazzale E. Fermi, 1, 80055 Portici, Italy.
Cascone, Ilaria
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Battista, Edoardo
  • Independent Researcher, Via Rampa 6, 03038 Roccasecca, Italy.
Peretti, Vincenzo
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Ciotola, Francesca
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.

Conflict of Interest Statement

The authors declare no conflict of interest.

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