Chronic active interstitial pancreatitis as a cause of transverse colonic obstruction and colic in a horse.
Abstract: A mature Quarter horse was euthanized following colic of 3 days duration. Postmortem, the large intestine, except the descending colon, was diffusely distended and associated with adhesion of the transverse colon to the pancreas, which had changes consistent with chronic active interstitial pancreatitis. Other lesions included hepatic fibrosis, erosive gastritis, and bilateral adrenal cortical hyperplasia. Pancréatite interstitielle chronique active comme cause d’une obstruction du côlon transversal et de coliques chez un cheval. Un cheval Quarter horse adulte a été euthanasié après des coliques d’une durée de 3 jours. À l’autopsie, il a été observé que le gros intestin, sauf le côlon descendant, présentait une distension diffuse et était associé à l’adhésion du côlon transversal au pancréas qui indiquait des changements conformes à une pancréatite interstitielle chronique active. Les autres lésions incluaient une fibrose hépatique, une gastrite érosive et une hyperplasie corticale bilatérale des surrénales.(Traduit par Isabelle Vallières).
Publication Date: 2015-11-06 PubMed ID: 26538675PubMed Central: PMC4608473
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Case Reports
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The study focuses on a case of a horse suffering from colic, where the cause was identified as chronic active interstitial pancreatitis leading to transverse colonic obstruction. Postmortem examination revealed other significant health issues in the horse including hepatic fibrosis, erosive gastritis, and bilateral adrenal cortical hyperplasia.
Objective of the Study
- The research was purposed to understand the health complications in a Quarter horse that was euthanized due to three days duration of colic.
- Particular attention was paid to understanding the cause of the colic and the role of chronic active interstitial pancreatitis in causing transverse colonic obstruction within the horse.
Methodology of the Study
- Postmortem examination of the horse was conducted to identify the health complications that might have contributed to its condition.
- The examination assessed the condition of the horse’s large intestine and other internal organs including the pancreas, liver, stomach and adrenal glands.
Key Findings of the Study
- Upon examination, it was discovered that most of the horse’s large intestine, excluding the descending colon, was significantly distended.
- A standout finding was an unusual adhesion of the transverse colon to the pancreas.
- The pancreas showed indications of chronic active interstitial pancreatitis, a severe inflammatory condition which was identified as the cause of the transverse colonic obstruction and colic in the horse.
- Additional findings included significant hepatic fibrosis (scarring of the liver), erosive gastritis (inflammation and erosion of the stomach lining), and bilateral adrenal cortical hyperplasia (enlargement of the adrenal glands).
Implications of the Research
- The findings of the study help clarify some of the potential causes and effects of severe colic in horses.
- The specific role of chronic active interstitial pancreatitis in causing transverse colonic obstruction in horses was identified, contributing valuable insights for future animal health and veterinary science research.
Cite This Article
APA
Lohmann KL, Allen AL.
(2015).
Chronic active interstitial pancreatitis as a cause of transverse colonic obstruction and colic in a horse.
Can Vet J, 56(11), 1177-1180.
Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences (Lohmann) and Department of Veterinary Pathology (Allen), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
- Department of Large Animal Clinical Sciences (Lohmann) and Department of Veterinary Pathology (Allen), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
MeSH Terms
- Animals
- Chronic Disease
- Colic / pathology
- Colic / veterinary
- Colonic Diseases / pathology
- Colonic Diseases / veterinary
- Horse Diseases / etiology
- Horse Diseases / pathology
- Horses
- Intestinal Obstruction / pathology
- Intestinal Obstruction / veterinary
- Male
- Pancreatitis / pathology
- Pancreatitis / veterinary
References
This article includes 14 references
- Johnson PJ, Wiedmeyer CE, Messer NT. Conditions of the equine pancreas.. Equine Vet Educ 2009;21:26–29.
- Newman SJ. Equine pancreatic disease: A review and characterization of the lesions of four cases (2005–2014). J Vet Diagn Invest 2015;27:92–96.
- Yamout SZ, Nieto JE, Anderson J, De Cock HE, Vapniarsky N, Aleman M. Pathological evidence of pancreatitis in 43 horses (1986–2011). Equine Vet J 2012;43:45–50.
- Charles JA. Pancreas.. In: Maxie MG, editor. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. 5th ed. Vol. 2. Toronto, Ontario: Saunders Elsevier; 2007. pp. 389–424.
- Cullen JM, Brown DL. Hepatobiliary system and exocrine pancreas.. In: Zachary JF, McGavin MD, editors. Pathologic Basis of Veterinary Disease. 5th ed. St. Louis, Missouri: Elsevier Mosby; 2012. pp. 405–457.
- Nickel R, Schummer A, Seiferle E. The Viscera of the Domestic Mammals.. 2nd ed. New York, New York: Springer-Verlag; 1979. pp. 99–122.pp. 180–203.
- Liu C, Crawford JM. The gastrointestinal tract.. In: Kurar V, Abbas AK, Fausto N, editors. Robbins and Cotran Pathologic Basis of Disease. 7th ed. Philadelphia, Pennsylvania: Saunders Elsevier; 2005. pp. 797–875.
- Fubini SL. Abdominal adhesions.. In: Mair T, Divers T, Ducharme N, editors. Manual of Equine Gastroenterology. Philadelphia, Pennsylvania: Saunders; 2002. pp. 209–211.
- Rakestraw P. Ileus.. In: Mair T, Divers T, Ducharme N, editors. Manual of Equine Gastroenterology. Philadelphia, Pennsylvania: Saunders; 2002. pp. 211–215.
- Koenig J, Cote N. Equine gastrointestinal motility — Ileus and pharmacological modification.. Can Vet J 2006;47:551–559.
- Brown CC, Baker DC, Barker IK. Alimentary system.. In: Maxie MG, editor. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. 5th ed. Vol. 2. Toronto, Ontario: Saunders Elsevier; 2007. pp. 1–296.
- Videla R, Andrews FM. New perspectives in equine gastric ulcer syndrome.. Vet Clin North Am Equine Pract 2009;25:283–301.
- Kapitonova MY, Kuznetsov SL, Khlebnikov VV, Zagrebin VL, Morozova ZCh, Degtyar YV. Immunohistochemical characteristic of the hypophysis in normal conditions and chronic stress.. Neurosci Behave Physiol 2010;40:97–102.
- Ulrich-Lai YM, Figueiredo HF, Ostrander MM, Choi DC, Engeland WC, Herman JP. Chronic stress induces adrenal hyperplasia and hypertrophy in a subregion-specific manner.. Am J Physiol Endocrinol Metab 2006;291:E965–E973.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
