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Microbial pathogenesis2021; 163; 105377; doi: 10.1016/j.micpath.2021.105377

Clinical and pathological examination of mycotoxicosis as an associated risk factor for colic in equine.

Abstract: A retrospective cohort study was conducted on two Egyptian horse farms with most of horses were suffered from abdominal pain to describe the associations between the occurrence of mycotoxicosis and equine colic. The farms owner complain was an unexpected increase in number of colic cases and deaths among horses. The association between colic and risk factors (sex, type of food either dry or mixed with roughages and hematobiochemical parameters) was compared using independent sample T-test. The associations between possible prognostic indicators for colic caused by mycotoxicosis was estimated using logistic regression analysis model. The cumulative incidence, incidence rates for colic attacks, survival rate among diseased horses were additionally estimated. Our results showed that a total of 24 out of the 132 horses suffered from colic due to feeding of ration contaminated with high percent of mycotoxin including Aflatoxins, Ochratoxins and or fusarium mycotoxins. The total cumulative incidence of colic due to mycotoxicosis was 19.7%. The horses fed on dry rations had more chance of developing colic than horses fed on mixed rations (P < 0.05). The overall incidence rate of colic due to mycotoxicosis was estimated at 18 colic attack/1000 horse/month. The mortality rate of horses suffered from colic due to mycotoxicosis was estimated at 5.9% (5/85), while the case fatality rate was estimated at 25% (n = 5/20). Inconclusion, our results showed that mycotoxicosis are considered an important risks factor for colic cases development in equine practice.
Publication Date: 2021-12-31 PubMed ID: 34974118DOI: 10.1016/j.micpath.2021.105377Google Scholar: Lookup
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  • Journal Article

Summary

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This study reveals that horses suffering from the disease ‘mycotoxicosis’ are at an increased risk of developing abdominal pain (colic). The common cause of mycotoxicosis in horses is the consumption of feed contaminated with harmful mycotoxins, leading to high incidences of colic and subsequently fatalities among horses.

Study Methodology

  • The research was a retrospective cohort study conducted on two Egyptian horse farms where many horses were suffering from abdominal pain.
  • The owner of the farms noted an unusual increase in the number of cases of colic and horse deaths.
  • Researchers compared the association between colic and risk factors like sex of the horse, type of feed (dry or mixed with roughages) and hematobiochemical parameters using a statistical method known as independent sample T-test.
  • The potential indicators which could predict the occurrence of colic caused by mycotoxicosis were determined using a logistic regression analysis model.

Findings of the Study

  • Out of 132 horses studied, 24 suffered from colic due to being fed a ration containing a high percentage of mycotoxins including Aflatoxins, Ochratoxins and Fusarium mycotoxins.
  • The cumulative incidence of colic due to mycotoxicosis was estimated at 19.7%.
  • The horses given dry rations were at greater risk of developing colic compared to those fed mixed rations.
  • The overall incidence rate of colic due to mycotoxicosis was projected at 18 colic attacks per 1000 horses each month.
  • The mortality rate of horses suffering from colic due to mycotoxicosis was calculated at 5.9% (5 out of 85 horses).
  • The case fatality rate was estimated at 25% (5 out of 20 cases).

Conclusion

  • The researchers concluded that mycotoxicosis is a significant risk factor for the development of colic cases in equine veterinary practice.

Cite This Article

APA
Gomaa N, Elemiri M, Hegazy Y, Zeineldin M, Nassif M, Alcala-Canto Y, Barbabosa-Pliego A, Rivas-Caceres RR, Abdelmegeid M. (2021). Clinical and pathological examination of mycotoxicosis as an associated risk factor for colic in equine. Microb Pathog, 163, 105377. https://doi.org/10.1016/j.micpath.2021.105377

Publication

ISSN: 1096-1208
NlmUniqueID: 8606191
Country: England
Language: English
Volume: 163
Pages: 105377
PII: S0882-4010(21)00651-3

Researcher Affiliations

Gomaa, N
  • Department of Animal Medicine, Faculty of Veterinary Medicine, Kafr-Elsheikh University, Egypt.
Elemiri, M
  • Department of Animal Medicine, Faculty of Veterinary Medicine, Kafr-Elsheikh University, Egypt.
Hegazy, Y
  • Department of Animal Medicine, Faculty of Veterinary Medicine, Kafr-Elsheikh University, Egypt.
Zeineldin, M
  • Department of Animal Medicine, Faculty of Veterinary Medicine, Benha University, Egypt.
Nassif, M
  • Department of Animal Medicine, Faculty of Veterinary Medicine, Kafr-Elsheikh University, Egypt.
Alcala-Canto, Y
  • Departamento de Parasitologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, Mexico.
Barbabosa-Pliego, A
  • Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de, México, Toluca, Mexico.
Rivas-Caceres, R R
  • Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Ciudad, Juárez, Chihuahua, Mexico. Electronic address: rrivas@uacj.mx.
Abdelmegeid, M
  • Department of Animal Medicine, Faculty of Veterinary Medicine, Kafr-Elsheikh University, Egypt.

MeSH Terms

  • Animals
  • Colic / epidemiology
  • Colic / veterinary
  • Horse Diseases / epidemiology
  • Horses
  • Mycotoxicosis / veterinary
  • Retrospective Studies
  • Risk Factors

Citations

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